KEGG   Homo sapiens (human): 113235
Entry
113235            CDS       T01001                                 
Symbol
SLC46A1, G21, HCP1, HsPCFT, PCFT, hPCFT
Name
(RefSeq) solute carrier family 46 member 1
  KO
K14613  MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa01523  Antifolate resistance
hsa04977  Vitamin digestion and absorption
hsa04978  Mineral absorption
Disease
H01252  Hereditary folate malabsorption
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04977 Vitamin digestion and absorption
    113235 (SLC46A1)
   04978 Mineral absorption
    113235 (SLC46A1)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    113235 (SLC46A1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    113235 (SLC46A1)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC46: Folate transporter
   113235 (SLC46A1)
 Major facilitator superfamily (MFS)
  Organic acid transporters
   Proton coupled folate transporter/heme carrier protein (PCFT/HCP) family [TC:2.A.1.50]
    113235 (SLC46A1)
SSDB
Motif
Pfam: MFS_1 Sugar_tr
Other DBs
NCBI-GeneID: 113235
NCBI-ProteinID: NP_542400
OMIM: 611672
HGNC: 30521
Ensembl: ENSG00000076351
UniProt: Q96NT5
Position
17:complement(28394642..28406592)
AA seq 459 aa
MEGSASPPEKPRARPAAAVLCRGPVEPLVFLANFALVLQGPLTTQYLWHRFSADLGYNGT
RQRGGCSNRSADPTMQEVETLTSHWTLYMNVGGFLVGLFSSTLLGAWSDSVGRRPLLVLA
SLGLLLQALVSVFVVQLQLHVGYFVLGRILCALLGDFGGLLAASFASVADVSSSRSRTFR
MALLEASIGVAGMLASLLGGHWLRAQGYANPFWLALALLIAMTLYAAFCFGETLKEPKST
RLFTFRHHRSIVQLYVAPAPEKSRKHLALYSLAIFVVITVHFGAQDILTLYELSTPLCWD
SKLIGYGSAAQHLPYLTSLLALKLLQYCLADAWVAEIGLAFNILGMVVFAFATITPLMFT
GYGLLFLSLVITPVIRAKLSKLVRETEQGALFSAVACVNSLAMLTASGIFNSLYPATLNF
MKGFPFLLGAGLLLIPAVLIGMLEKADPHLEFQQFPQSP
NT seq 1380 nt   +upstreamnt  +downstreamnt
atggaggggagcgcgagccccccggaaaagccccgcgcccgccctgcggctgccgtgctg
tgccggggcccggtagagccgctggtcttcctggccaactttgccttggtcctgcagggc
ccgctcaccacgcagtatctgtggcaccgcttcagcgccgacctcggctacaatggcacc
cgccaaagggggggctgcagcaaccgcagcgcggaccccaccatgcaggaagtggagacc
cttacctcccactggaccctctacatgaacgtgggcggcttcctggtggggctcttctcg
tccaccctgctgggagcttggagcgacagtgtgggccgccgcccgctgctagtgctggcc
tcgctgggcctgctgctccaggccctagtgtccgtttttgtggtgcagctgcagctccac
gtcggctacttcgtgctgggtcgcatcctttgtgccctcctcggcgacttcggtggcctt
ctggctgctagctttgcgtccgtggcagatgtcagctccagtcgcagccgcaccttccgg
atggccctgctggaagccagcatcggggtggctgggatgctggcaagcctcctcgggggc
cactggctccgggcccagggttatgccaaccccttctggctggccttggccttgctgata
gccatgactctctatgcagctttctgctttggtgagaccttaaaggagccaaagtccacc
cggctcttcacgttccgtcaccaccgatccattgtccagctctatgtggctcccgcccca
gagaagtccaggaaacatttagccctctactcactggccatcttcgtggtgatcactgtg
cactttggggcccaggacatcttaaccctttatgaactaagcacacccctctgctgggac
tccaaactaatcggctatggttctgcagctcagcatctcccctacctcaccagcctgctg
gccctgaagctcctgcagtactgcctggccgatgcctgggtagctgagatcggcctggcc
ttcaacatcctggggatggtggtctttgcctttgccactatcacgcctctcatgttcaca
ggatatgggttgcttttcctgtcattagtcatcacacctgtcatccgggctaaactctcc
aagctggtgagagagacagagcagggtgctctcttttctgctgtggcctgtgtgaatagc
ctggccatgctgacggcctccggcatcttcaactcactctacccagccactctgaacttt
atgaaggggttccccttcctcctgggagctggcctcctgctcatcccggctgttctgatt
gggatgctggaaaaggctgatcctcacctcgagttccagcagtttccccagagcccctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (33)   
   RefSeq(nuc) (7)   
   GenBank (13)   
   EMBL (13)   
Protein domain (2)   
   Pfam (2)   
All databases (68)   

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