KEGG T01001: 1142

Homo sapiens (human): 1142

Entry

1142              CDS       T01001

Symbol

CHRNB3

Name

(RefSeq) cholinergic receptor nicotinic beta 3 subunit

K04814

nicotinic acetylcholine receptor beta-3

Organism

hsa Homo sapiens (human)

Pathway

hsa04080

Neuroactive ligand-receptor interaction

Drug target

Acetylcholine (DG01133):

D00999<JP/US>

Atracurium (DG00771):

D00758<US>

Cisatracurium:

D00759<US>

Cytisinicline:

D07770

Dimethyltubocurarine:

D07272

Doxacurium chloride:

D00760

Fazadinium bromide:

D07273

Hexamethonium bromide:

D02204

Lobeline (DG01287):

D02202 D02364 D08138

Mecamylamine (DG00252):

D00611<US>

Mivacurium chloride:

D00763

Nicotine (DG00994):

D03365<JP/US> D05156 D05157

Pancuronium (DG00769):

D00492

Pipecuronium bromide:

D00764

Rocuronium bromide:

D00765<JP/US>

Tubocurarine (DG00767):

D02207 D08655

Vecuronium (DG00770):

D00767<US>

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    1142 (CHRNB3)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    1142 (CHRNB3)
Ion channels [BR:hsa04040]
Ligand-gated channels
  Acetylcholine (nicotinic)
   1142 (CHRNB3)

SSDB

Motif

Pfam:

Neur_chan_LBD Neur_chan_memb PepSY_TM DUF3945

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

Position

8:42697366..42737407

AA seq 458 aa
MLPDFMLVLIVLGIPSSATTGFNSIAENEDALLRHLFQGYQKWVRPVLHSNDTIKVYFGL
KISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFEN
ADGRFEGSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTM
VDLILINENVDRKDFFDNGEWEILNAKGMKGNRRDGVYSYPFITYSFVLRRLPLFYTLFL
IIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYL
LFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFLQKLPKLLCMKDHVDRYSSPE
KEESQPVVKGKVLEKKKQKQLSDGEKVLVAFLEKAADSIRYISRHVKKEHFISQVVQDWK
FVAQVLDRIFLWLFLIVSVTGSVLIFTPALKMWLHSYH

NT seq 1377 nt +upstreamnt +downstreamnt
atgctcccagattttatgctggttctcatcgtccttggcatcccttcctcagccaccaca
ggtttcaactcaatcgccgaaaatgaagatgccctcctcagacatttgttccaaggttat
cagaaatgggtccgccctgtattacattctaatgacaccataaaagtatattttggattg
aaaatatcccagcttgtagatgtggatgaaaagaatcagctgatgacaaccaatgtgtgg
ctcaaacaggaatggacagaccacaagttacgctggaatcctgatgattatggtgggatc
cattccattaaagttccatcagaatctctgtggcttcctgacatagttctctttgaaaat
gctgacggccgcttcgaaggctccctgatgaccaaggtcatcgtgaaatcaaacggaact
gttgtctggacccctcccgccagctacaaaagctcctgcaccatggacgtcacgtttttc
ccgttcgaccgacagaactgctccatgaagtttggatcctggacttatgatggcaccatg
gttgacctcattttgatcaatgaaaatgtcgacagaaaagacttcttcgataacggagaa
tgggaaatactgaacgcaaaggggatgaaggggaacagaagggacggcgtgtactcctat
ccctttatcacgtattccttcgtcctgagacgcctgcctttattctataccctctttctc
atcatcccctgcctggggctgtctttcctaacagttcttgtgttctatttaccttcggat
gaaggagaaaaactttcattatccacatcggtcttggtttctctgacagttttcctttta
gtgattgaagaaatcatcccatcgtcttccaaagtcattcctctcattggagagtacctg
ctgttcatcatgatttttgtgaccctgtccatcattgttaccgtgtttgtcattaacgtt
caccacagatcttcttccacgtaccaccccatggccccctgggttaagaggctctttctg
cagaaacttccaaaattactttgcatgaaagatcatgtggatcgctactcatccccagag
aaagaggagagtcaaccagtagtgaaaggcaaagtcctcgaaaaaaagaaacagaaacag
cttagtgatggagaaaaagttctagttgcttttttggaaaaagctgctgattccattaga
tacatttcgagacatgtgaagaaagaacattttatcagccaggtagtacaagactggaaa
tttgtagctcaagttcttgaccgaatcttcctgtggctctttctgatagtgtcagtaaca
ggctcggttctgatttttacccctgctttgaagatgtggctacatagttaccattag

DBGET integrated database retrieval system