KEGG   Homo sapiens (human): 115201
Entry
115201            CDS       T01001                                 
Symbol
ATG4A, APG4A, AUTL2, HsAPG4A
Name
(RefSeq) autophagy related 4A cysteine peptidase
  KO
K08342  cysteine protease ATG4 [EC:3.4.22.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04136  Autophagy - other
hsa04140  Autophagy - animal
Network
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06182  Shigella
nt06532  Autophagy
  Element
N00156  Autophagy-vesicle nucleation/elongation/maturation, LC3-II formation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    115201 (ATG4A)
   04136 Autophagy - other
    115201 (ATG4A)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    115201 (ATG4A)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    115201 (ATG4A)
   03029 Mitochondrial biogenesis [BR:hsa03029]
    115201 (ATG4A)
Peptidases and inhibitors [BR:hsa01002]
 Cysteine peptidases
  Family C54: Aut2 peptidase family
   115201 (ATG4A)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Autophagosome formation proteins
   Atg8 conjugation proteins
    115201 (ATG4A)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Autophagy-related proteins
    115201 (ATG4A)
SSDB
Motif
Pfam: Peptidase_C54 ATG4_LIR
Other DBs
NCBI-GeneID: 115201
NCBI-ProteinID: NP_443168
OMIM: 300663
HGNC: 16489
Ensembl: ENSG00000101844
UniProt: Q8WYN0
Structure
Position
X:108088829..108154671
AA seq 398 aa
MESVLSKYEDQITIFTDYLEEYPDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRK
FSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQKEQPKEYQRILQCFLD
RKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIE
DIKKMCRVLPLSADTAGDRPPDSLTASNQSKGTSAYCSAWKPLLLIVPLRLGINQINPVY
VDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDTEENGTVNDQTF
HCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLRMFELVQKHPSHWP
PFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV
NT seq 1197 nt   +upstreamnt  +downstreamnt
atggagtcagttttatccaagtatgaagatcagattactattttcactgactacctagaa
gaatatccagatacagatgagctggtatggatcttagggaagcagcatctccttaaaaca
gaaaaatctaagctgttgtctgatataagtgctcgtctatggtttacatacagaaggaaa
ttttcaccaattggtggaacgggcccttcatcagatgctggttggggatgtatgctacgc
tgtggacagatgatgctggctcaagcccttatctgtagacacttgggaagggactggagc
tgggagaaacaaaaagaacaacccaaagaataccaacgcatcctacagtgcttcttagat
agaaaagattgttgctactctatccatcaaatggcacaaatgggtgtaggagaagggaaa
tcaattggagaatggtttggaccaaatacagttgcacaggtgttaaaaaaacttgcttta
tttgacgaatggaattccttggctgtttatgtttcaatggataacacagtggtcattgaa
gatatcaaaaaaatgtgccgtgtccttcccttgagtgctgacacagctggtgacaggcct
cccgattctttaactgcttcaaaccagagtaagggcacctctgcctactgctcagcctgg
aaacccctgctgctcattgtgccccttcgcctgggcataaaccaaatcaatcctgtctat
gttgatgcattcaaagagtgttttaagatgccacagtctttaggggcattaggaggaaaa
ccaaataacgcgtattatttcataggattcttaggtgacgagctcatcttcttggaccct
catacaacccagacctttgttgacactgaagagaatggaacggttaatgaccagactttc
cattgcctgcagtccccacagcgaatgaacatcctaaacctggatccttcagttgcattg
ggatttttctgcaaagaagaaaaagactttgataactggtgtagccttgttcagaaggaa
attctaaaggagaatttaaggatgtttgaattagttcagaaacatccatcacactggcct
ccctttgtacctccagccaagccagaagtgacaaccactggggcagaattcattgactct
actgagcaactggaggagtttgatctggaggaagattttgagattctgagtgtgtag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (4)   
   KEGG NETWORK (4)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (17)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (15)   
DNA sequence (40)   
   RefSeq(nuc) (16)   
   GenBank (12)   
   EMBL (12)   
3D Structure (1)   
   PDB (1)   
Protein domain (2)   
   Pfam (2)   
All databases (86)   

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