KEGG   Homo sapiens (human): 116447
Entry
116447            CDS       T01001                                 
Symbol
TOP1MT
Name
(RefSeq) DNA topoisomerase I mitochondrial
  KO
K03163  DNA topoisomerase I [EC:5.6.2.1]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:hsa03032]
    116447 (TOP1MT)
Enzymes [BR:hsa01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.1  DNA topoisomerase
     116447 (TOP1MT)
DNA replication proteins [BR:hsa03032]
 Eukaryotic type
  DNA Topoisomerases
   116447 (TOP1MT)
SSDB
Motif
Pfam: Topoisom_I Topoisom_I_N Topo_C_assoc DUF4407
Other DBs
NCBI-GeneID: 116447
NCBI-ProteinID: NP_443195
OMIM: 606387
HGNC: 29787
Ensembl: ENSG00000184428
UniProt: Q969P6 E5KMK7
Position
8:complement(143309324..143359977)
AA seq 601 aa
MRVVRLLRLRAALTLLGEVPRRPASRGVPGSRRTQKGSGARWEKEKHEDGVKWRQLEHKG
PYFAPPYEPLPDGVRFFYEGRPVRLSVAAEEVATFYGRMLDHEYTTKEVFRKNFFNDWRK
EMAVEEREVIKSLDKCDFTEIHRYFVDKAAARKVLSREEKQKLKEEAEKLQQEFGYCILD
GHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRITPEDVVINCSRDSKIPEPPAGHQWKEV
RSDNTVTWLAAWTESVQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFVDEIRSQYRAD
WKSREMKTRQRAVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHVQLHPEADGCQHV
VEFDFLGKDCIRYYNRVPVEKPVYKNLQLFMENKDPRDDLFDRLTTTSLNKHLQELMDGL
TAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSM
QNLQTKIQAKKEQVAEARAELRRARAEHKAQGDGKSRSVLEKKRRLLEKLQEQLAQLSVQ
ATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRERFAWALAMAGEDFE
F
NT seq 1806 nt   +upstreamnt  +downstreamnt
atgcgcgtggtgcggctgctgcggctccgggcggctctgacgctgctcggggaggtcccc
cgccgcccggcctcccggggtgtcccgggctcgcgcaggacgcagaagggcagtggagcc
aggtgggagaaggagaagcacgaagacggggtgaagtggagacagctggagcacaagggc
ccgtacttcgcacccccatacgagccccttcccgacggagtgcgtttcttctatgaagga
aggcctgtgagattgagcgtggcagcggaggaggtcgccactttttatgggaggatgtta
gatcatgaatacacaacaaaggaggttttccggaagaacttcttcaatgactggcgaaag
gaaatggcggtggaagagagggaagtcatcaagagcctggacaagtgtgacttcacggag
atccacagatactttgtggacaaggccgcagcccggaaagtcctgagcagggaggagaag
cagaagctaaaagaagaggcagaaaaacttcagcaagagttcggctactgtattttagat
ggtcaccaagaaaaaataggcaacttcaagattgagccgcctggcttgttccgtggccgt
ggcgaccatcccaagatggggatgctgaagagaaggatcacgccagaggatgtggttatc
aactgcagcagggactcgaagatccccgagccgccggcggggcaccagtggaaggaggtg
cgctccgataacaccgtcacgtggctggcagcttggaccgagagcgttcagaactccatc
aagtacatcatgctgaacccttgctcgaagctgaagggggagacagcttggcagaagttt
gaaacagctcgacgcctgcggggatttgtggacgagatccgctcccagtaccgggctgac
tggaagtctcgggaaatgaagacgagacagcgggcggtggccctgtatttcatcgataag
ctggcactgagagcaggaaatgagaaggaggacggtgaggcggccgacaccgtgggctgc
tgttccctccgcgtggagcacgtccagctgcacccggaggccgatggctgccaacacgtg
gtggaatttgacttcctggggaaggactgcatccgctactacaacagagtgccggtggag
aagccggtgtacaagaacttacagctctttatggagaacaaggacccccgggacgacctc
ttcgacaggctgaccacgaccagcctgaacaagcacctccaggagctgatggacgggctg
acggccaaggtgttccggacctacaacgcctccatcactctgcaggagcagctgcgggcc
ctgacgcgcgccgaggacagcatagcagctaagatcttatcctacaaccgagccaaccga
gtcgtggccattctctgcaaccatcagcgagcaacccccagtacgttcgagaagtcgatg
cagaatctccagacgaagatccaggcaaagaaggagcaggtggctgaggccagggcagag
ctgaggagggcgagggctgagcacaaagcccaaggggatggcaagtccaggagtgtcctg
gagaagaagaggcggctcctggagaagctgcaggagcagctggcgcagctgagtgtgcag
gccacggacaaggaggagaacaagcaggtggccctgggcacgtccaagctcaactacctg
gaccccaggatcagcattgcctggtgcaagcggttcagggtgccagtggagaagatctac
agcaaaacacagcgggagaggttcgcctgggctctcgccatggcaggagaagactttgaa
ttctaa

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Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (13)   
   OC (1)   
Protein sequence (37)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (34)   
DNA sequence (68)   
   RefSeq(nuc) (34)   
   GenBank (17)   
   EMBL (17)   
Protein domain (4)   
   Pfam (4)   
All databases (138)   

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