| Entry |
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| Symbol |
CCR4, CC-CKR-4, CD194, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5
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| Name |
(RefSeq) C-C motif chemokine receptor 4
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| KO |
| K04179 | C-C chemokine receptor type 4 |
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| Organism |
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| Pathway |
| hsa04060 | Cytokine-cytokine receptor interaction |
| hsa04061 | Viral protein interaction with cytokine and cytokine receptor |
| hsa05167 | Kaposi sarcoma-associated herpesvirus infection |
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| Network |
nt06164 Kaposi sarcoma-associated herpesvirus (KSHV) nt06224 CXCR signaling (cancer) nt06533 Chemokine signaling |
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| Element |
| N00153 | CCR/CXCR-GNB/G-PI3K-RAC signaling pathway |
| N00462 | KSHV vCCL1/2/3 to CCR signaling pathway |
| N01746 | CCR/CXCR-GNB/G-PI3K signaling pathway |
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| Drug target |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
1233 (CCR4)
04061 Viral protein interaction with cytokine and cytokine receptor
1233 (CCR4)
09150 Organismal Systems
09151 Immune system
04062 Chemokine signaling pathway
1233 (CCR4)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
1233 (CCR4)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
1233 (CCR4)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04030 G protein-coupled receptors [BR:hsa04030]
1233 (CCR4)
04050 Cytokine receptors [BR:hsa04050]
1233 (CCR4)
04090 CD molecules [BR:hsa04090]
1233 (CCR4)
G protein-coupled receptors [BR:hsa04030]
Rhodopsin family
Chemokine
CC Chemokine
1233 (CCR4)
Cytokine receptors [BR:hsa04050]
Chemokine receptors
CC Chemokine
1233 (CCR4)
CD molecules [BR:hsa04090]
Proteins
1233 (CCR4)
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| SSDB |
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| Motif |
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| Other DBs |
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| Position |
3:32951644..32956349
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| AA seq |
360 aa
MNPTDIADTTLDESIYSNYYLYESIPKPCTKEGIKAFGELFLPPLYSLVFVFGLLGNSVV
VLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGYYAADQWVFGLGLCKMISWMYLVG
FYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATWSVAVFASLPGFLFSTCYT
ERNHTYCKTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTLQHCKNEKKNKA
VKMIFAVVVLFLGFWTPYNIVLFLETLVELEVLQDCTFERYLDYAIQATETLAFVHCCLN
PIIYFFLGEKFRKYILQLFKTCRGLFVLCQYCGLLQIYSADTPSSSYTQSTMDHDLHDAL |
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| NT seq |
1083 nt +upstreamnt +downstreamnt
atgaaccccacggatatagcagacaccaccctcgatgaaagcatatacagcaattactat
ctgtatgaaagtatccccaagccttgcaccaaagaaggcatcaaggcatttggggagctc
ttcctgcccccactgtattccttggtttttgtatttggtctgcttggaaattctgtggtg
gttctggtcctgttcaaatacaagcggctcaggtccatgactgatgtgtacctgctcaac
cttgccatctcggatctgctcttcgtgttttccctccctttttggggctactatgcagca
gaccagtgggtttttgggctaggtctgtgcaagatgatttcctggatgtacttggtgggc
ttttacagtggcatattctttgtcatgctcatgagcattgatagatacctggcaattgtg
cacgcggtgttttccttgagggcaaggaccttgacttatggggtcatcaccagtttggct
acatggtcagtggctgtgttcgcctcccttcctggctttctgttcagcacttgttatact
gagcgcaaccatacctactgcaaaaccaagtactctctcaactccacgacgtggaaggtt
ctcagctccctggaaatcaacattctcggattggtgatccccttagggatcatgctgttt
tgctactccatgatcatcaggaccttgcagcattgtaaaaatgagaagaagaacaaggcg
gtgaagatgatctttgccgtggtggtcctcttccttgggttctggacaccttacaacata
gtgctcttcctagagaccctggtggagctagaagtccttcaggactgcacctttgaaaga
tacttggactatgccatccaggccacagaaactctggcttttgttcactgctgccttaat
cccatcatctacttttttctgggggagaaatttcgcaagtacatcctacagctcttcaaa
acctgcaggggcctttttgtgctctgccaatactgtgggctcctccaaatttactctgct
gacacccccagctcatcttacacgcagtccaccatggatcatgatctccatgatgctctg
tag |
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