KEGG   Homo sapiens (human): 1267
Entry
1267              CDS       T01001                                 
Symbol
CNP, CNP1, HLD20
Name
(RefSeq) 2',3'-cyclic nucleotide 3' phosphodiesterase
  KO
K01121  2',3'-cyclic-nucleotide 3'-phosphodiesterase [EC:3.1.4.37]
Organism
hsa  Homo sapiens (human)
Disease
H00679  Hypomyelinating leukodystrophy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    1267 (CNP)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.37  2',3'-cyclic-nucleotide 3'-phosphodiesterase
     1267 (CNP)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of oligodendrocytes
   1267 (CNP)
SSDB
Motif
Pfam: CNPase AAA_33 6PF2K nSTAND3 AAA_22 AAA AAA_17 KTI12 ABC_tran AAA_14 AAA_30 AAA_18 Zeta_toxin AAA_16 NACHT DUF4823 NB-ARC Viral_helicase1 AAA_5 TsaE AAA_19
Other DBs
NCBI-GeneID: 1267
NCBI-ProteinID: NP_149124
OMIM: 123830
HGNC: 2158
Ensembl: ENSG00000173786
UniProt: P09543
Structure
Position
17:41966795..41977740
AA seq 421 aa
MNRGFSRKSHTFLPKIFFRKMSSSGAKDKPELQFPFLQDEDTVATLLECKTLFILRGLPG
SGKSTLARVIVDKYRDGTKMVSADAYKITPGARGAFSEEYKRLDEDLAAYCRRRDIRILV
LDDTNHERERLEQLFEMADQYQYQVVLVEPKTAWRLDCAQLKEKNQWQLSADDLKKLKPG
LEKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRQFVPGDEPREKMDLVT
YFGKRPPGVLHCTTKFCDYGKAPGAEEYAQQDVLKKSYSKAFTLTISALFVTPKTTGARV
ELSEQQLQLWPSDVDKLSPTDNLPRGSRAHITLGCAADVEAVQTGLDLLEILRQEKGGSR
GEEVGELSRGKLYSLGNGRWMLTLAKNMEVRAIFTGYYGKGKPVPTQGSRKGGALQSCTI
I
NT seq 1266 nt   +upstreamnt  +downstreamnt
atgaacagaggcttctcccgaaaaagccacacattcctgcccaagatcttcttccgcaag
atgtcatcctcaggggccaaggacaagcctgagctgcagtttcccttccttcaggatgag
gacacagtggccacgctgctagagtgcaagacgctcttcatcttgcgcggcctgccagga
agcggcaagtccacgctggcacgggtcatcgtggacaagtaccgtgatggcaccaagatg
gtgtcggctgacgcttacaagatcacccccggcgctcgaggagccttctccgaggagtac
aagcggctcgatgaggacctggctgcctactgccgccgccgggacatcagaattcttgtg
cttgatgacaccaaccacgaacgggaacggctggagcagctctttgaaatggccgaccag
taccagtaccaggtggtgctggtggagcccaagacggcgtggcggctggactgtgcccag
ctcaaggagaagaaccagtggcagctgtcggctgatgacctgaagaagctgaagcctggg
ctggagaaggacttcctgccgctctacttcggctggttcctgaccaagaagagctctgag
accctccgcaaagccggccaggtcttcctggaagagctggggaaccacaaggccttcaag
aaggagctgcgacaattcgtccctggggatgagcccagggagaagatggacttggtcacc
tactttggaaagagacccccaggcgtgctgcattgcacaaccaagttttgtgactacggg
aaggctcccggggcagaggagtacgctcaacaagatgtgttaaagaaatcttactccaag
gccttcacgctgaccatctctgccctctttgtgacacccaagacgactggggcccgggtg
gagttaagcgagcagcaactgcagttgtggccgagtgatgtggacaagctgtcacccact
gacaacctgccgcgggggagccgcgcccacatcaccctcggctgtgcagctgacgtagag
gccgtgcagacgggccttgacctcttagagattctgcggcaggagaaggggggcagccga
ggcgaggaggtgggcgagctaagccggggcaagctctattccttgggcaatgggcgctgg
atgctgaccctggccaagaacatggaggtcagggccatcttcacggggtactacgggaaa
ggcaaacctgtgcccacgcaaggtagccggaaggggggcgccttgcagtcctgcaccatc
atatga

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Ontology (3)   
   KEGG BRITE (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (38)   
   RefSeq(nuc) (4)   
   GenBank (17)   
   EMBL (17)   
3D Structure (1)   
   PDB (1)   
Protein domain (21)   
   Pfam (21)   
All databases (87)   

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