KEGG   Homo sapiens (human): 137492
Entry
137492            CDS       T01001                                 
Symbol
VPS37A, HCRP1, PQBP2, SPG53
Name
(RefSeq) VPS37A subunit of ESCRT-I
  KO
K12185  ESCRT-I complex subunit VPS37
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
Disease
H00266  Hereditary spastic paraplegia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    137492 (VPS37A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    137492 (VPS37A)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    137492 (VPS37A)
Membrane trafficking [BR:hsa04131]
 Endosome - Lysosome transport
  Endosomal sorting complexes required for transport (ESCRT)
   ESCRT-I complex
    137492 (VPS37A)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   137492 (VPS37A)
  Exosomal proteins of colorectal cancer cells
   137492 (VPS37A)
SSDB
Motif
Pfam: Mod_r UEV HEPN_SAV2148 UQ_con
Other DBs
NCBI-GeneID: 137492
NCBI-ProteinID: NP_689628
OMIM: 609927
HGNC: 24928
Ensembl: ENSG00000155975
UniProt: Q8NEZ2
Structure
Position
8:17246958..17333455
AA seq 397 aa
MSWLFPLTKSASSSAAGSPGGLTSLQQQKQRLIESLRNSHSSIAEIQKDVEYRLPFTINN
LTININILLPPQFPQEKPVISVYPPIRHHLMDKQGVYVTSPLVNNFTMHSDLGKIIQSLL
DEFWKNPPVLAPTSTAFPYLYSNPSGMSPYASQGFPFLPPYPPQEANRSITSLSVADTVS
SSTTSHTTAKPAAPSFGVLSNLPLPIPTVDASIPTSQNGFGYKMPDVPDAFPELSELSVS
QLTDMNEQEEVLLEQFLTLPQLKQIITDKDDLVKSIEELARKNLLLEPSLEAKRQTVLDK
YELLTQMKSTFEKKMQRQHELSESCSASALQARLKVAAHEAEEESDNIAEDFLEGKMEID
DFLSSFMEKRTICHCRRAKEEKLQQAIAMHSQFHAPL
NT seq 1194 nt   +upstreamnt  +downstreamnt
atgagctggctttttcccctgaccaagagcgcctcctcctccgcggctgggtcccccggt
ggcctcaccagcctccagcagcagaagcagcgcctgatcgagtccctccggaactcacac
tccagtatagccgaaatacagaaagatgtggaatacagattgccattcaccataaacaac
ctgacaattaacattaatatattgcttcctccacagtttcctcaggaaaaaccagtgatc
agtgtttatccaccaatacgacatcacttaatggataaacaaggagtgtatgttacctct
ccattagtaaacaattttacaatgcactcagatcttggaaaaattattcagagtctgttg
gatgagttttggaagaatcctccagttttagctcctacttcaacagcatttccttatcta
tacagtaacccaagtgggatgtctccttatgcttctcagggttttccatttcttcctcca
tatcctccacaagaagcaaacaggagtatcacttctttatctgttgctgacactgtttct
tcttcaacaacaagtcataccacagccaagcctgccgctccttcatttggtgtcctttca
aatctgccattacccattcccacagtggatgcttcaataccgacaagccaaaatggtttt
gggtacaagatgccagatgtccctgatgcatttccagaactctcagaactaagtgtgtca
caactcacagatatgaatgaacaagaggaggtattactagaacagtttctgactttgcct
caactaaaacaaattattaccgacaaagatgacttagtaaaaagtattgaggaactagca
agaaaaaatctccttttggagcccagcttggaagccaaaagacaaactgttttagataag
tatgaattacttacacagatgaagtccactttcgaaaagaagatgcaaaggcagcatgaa
cttagtgagagctgtagtgcaagtgcccttcaggcaagattgaaagtagctgcacatgaa
gctgaggaagaatctgataatattgcagaagacttcttggagggaaagatggaaatagat
gattttctcagtagcttcatggaaaagagaacaatttgccactgtagaagagccaaggaa
gagaaacttcagcaggcgatagcaatgcacagccaatttcatgctccactatag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (17)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (15)   
DNA sequence (51)   
   RefSeq(nuc) (27)   
   GenBank (12)   
   EMBL (12)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   Pfam (4)   
All databases (93)   

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