KEGG   Homo sapiens (human): 139189
Entry
139189            CDS       T01001                                 
Symbol
DGKK
Name
(RefSeq) diacylglycerol kinase kappa
  KO
K00901  diacylglycerol kinase (ATP) [EC:2.7.1.107]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00561  Glycerolipid metabolism
hsa00564  Glycerophospholipid metabolism
hsa01100  Metabolic pathways
hsa04070  Phosphatidylinositol signaling system
hsa04072  Phospholipase D signaling pathway
hsa05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    139189 (DGKK)
   00564 Glycerophospholipid metabolism
    139189 (DGKK)
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    139189 (DGKK)
   04072 Phospholipase D signaling pathway
    139189 (DGKK)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    139189 (DGKK)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.107  diacylglycerol kinase (ATP)
     139189 (DGKK)
SSDB
Motif
Pfam: DAGK_acc DAGK_cat PH C1_1 Prok-RING_1 PH_3 YegS_C
Other DBs
NCBI-GeneID: 139189
NCBI-ProteinID: NP_001013764
OMIM: 300837
HGNC: 32395
Ensembl: ENSG00000274588
UniProt: Q5KSL6
Position
X:complement(50365409..50470825)
AA seq 1271 aa
MDRGAAAAQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPE
LAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATE
SAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPC
LLQCPVDTRERGLKTSPSPSPSPSPRTPMSWSRIKKILKEGPMLKNCNSFKRWKLRYFLV
QGQKLYFAHHPAFAHFETIDLSQATVAESSCRNLCHSFCVITPQRKITLAAPNRKDMEEW
INIIKTIQQGEIYKIPAAENNPFLVGMHCWYSSYSHRTQHCNVCRESIPALSRDAIICEV
CKVKSHRLCALRASKDCKWNTLSITDDLLLPADEVNMPHQWVEGNMPVSSQCAVCHESCG
SYQRLQDFRCLWCNSTVHDDCRRRFSKECCFRSHRSSVIPPTALSDPKGDGQLVVSSDFW
NLDWSSACSCPLLIFINSKSGDHQGIVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFA
RFRILVCGGDGSVSWVLSLIDAFGLHEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLD
ILNRVEQASVRILDRWSVMIRETPRQTPLLKGQVEMDVPRFEAAAIQHLESAATELNKIL
KAKYPTEMIIATRFLCSAVEDFVVDIVKAWGQIKQNNTAIVSVILKSDLMYDRLSVLIDV
LAEEAAATSAEKSATEYADSSKADRKPFIPQIDHIAKCKLELATKAQSLQKSLKLIIFQV
EQALDEESRQTISVKNFSSTFFLEDDPEDINQTSPRRRSRRGTLSSISSLKSEDLDNLNL
DHLHFTPESIRFKEKCVMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGT
KELLQRSYRKLEERVHLECDGETISLPNLQGIVVLNITSYAGGINFWGSNTATTEYEAPA
IDDGKLEVVAIFGSVQMAMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPG
LIKIRYKNAAQMLTRDRDFENSMKMWEYKHTEIQAAPQPQLDFQDSQESLSDEEYAQMQH
LARLAENLISKLNDLSKIHQHVSVLMGSVNASANILNDIFYGQDSGNEMGAASCIPIETL
SRNDAVDVTFSLKGLYDDTTAFLDEKLLRSAEDETALQSALDAMNKEFKKLSEIDWMNPI
FVPEEKSSDTDSRSLRLKIKFPKLGKKKVEEERKPKSGQSVQSFIGNLWHRRHREDEAEG
DDPLTPSRSQL
NT seq 3816 nt   +upstreamnt  +downstreamnt
atggaccgcggagctgccgcagcccagggcactgccccgcctcaggatggagagcagccc
gctgagtctccagagcctccgccgccttggccgccgccgccaccaccaccggctccgccg
ccggctccgccgctgctctccgaggcttcgccagaacccataccagagccctgtccagag
cttgctccaggtccctgtccagaggcgacctcagaatcagccacagaactgtacacagaa
ccgaccccagaaccagccacagagccggcctcagaaccggccccagaacctgccacagag
ccggccccagaacctgccacagagccggccccagaaccggccccagaacctgccacagag
tctgccccagagccgactccagaacctgccctagagtcggtcccagagccggccccagag
ctgactccagaagttgccccagagctggccccagagccgaccccagaacctgtgacagag
ctggccccagagttctgccctgaggcggctccagagttccgtccaagtccagcaccatgt
ctattgcaatgtccggtggacactcgagagagaggtctaaagacctcgccatcgccatcg
ccatcgccatcgcccagaacgccaatgtcgtggtccagaataaagaaaatattgaaggaa
ggacctatgctgaagaactgtaactctttcaagagatggaagcttagatattttctggtt
caaggacagaagctctactttgcacaccatcccgcgtttgcacactttgaaacgattgat
ctgtctcaagccactgtggcagaaagcagctgtagaaacctttgccacagtttttgtgtt
attacaccacaacgaaaaatcactctggctgcacccaaccggaaagacatggaagaatgg
attaacatcataaaaaccatccaacagggagaaatttataagatacctgcagcagaaaac
aacccttttcttgttggaatgcattgttggtactccagttacagccaccggacccagcac
tgcaatgtttgtcgagagagcattcctgccttatctagagatgccatcatctgtgaagtg
tgcaaagtgaaatctcacagattgtgtgctttgagagcaagcaaagactgcaagtggaat
acattgtctatcactgatgacctccttctgcctgcagatgaagtaaacatgccccatcaa
tgggtagaaggaaacatgcctgtcagctctcagtgtgcagtgtgtcatgagagctgtggc
agttatcaaagacttcaagacttccgctgcctgtggtgtaattctacggtgcatgatgac
tgtaggagacggttttccaaggaatgttgcttcagaagccatcgctcatcagtcattcct
cccactgctctaagcgaccccaaaggcgatggccaattagtagtatcttcagacttctgg
aatcttgattggtcatcagcctgttcatgtcccttgctcatcttcatcaactccaaaagt
ggcgatcatcaggggatcgtcttcctccgaaaattcaagcaataccttaacccatctcaa
gtgttcgacttattgaagggtggacctgaagcagggctgtctatgttcaagaactttgct
cgctttcgcattctggtttgtggtggagatggcagcgtgagctgggtcttatctctgatt
gatgcctttggattacatgaaaagtgtcagttggcagtcatcccacttggaaccggcaat
gatctggctcgtgttctgggctggggtgcattctggaacaaaagcaagtcacctctggac
atcctcaacagagtggagcaggctagtgtgaggatcctagacagatggagtgtgatgatt
cgtgagactcccagacaaaccccgctgctaaaaggacaggttgaaatggatgtaccacga
tttgaggctgctgccatccaacacttagaatctgcagccaccgagttgaacaaaatcctg
aaggccaagtaccccacagagatgatcatcgcaaccagattcttgtgttcagctgtggaa
gattttgtggttgatattgtaaaggcctggggtcagataaaacagaacaacactgcaata
gtgtctgtgattttgaaaagtgacttaatgtatgataggctcagtgtcctgatcgatgtc
ctggctgaggaggcagcagctacttctgctgaaaaaagtgctacagaatatgcagacagc
agcaaggcagataggaagcccttcattcctcaaatagaccacatagccaagtgcaagttg
gagctggctacaaaggcccagagtctccagaaatccttgaaactcatcatatttcaagtt
gaacaagctctggatgaggaaagcagacagacaatatctgttaagaactttagttcaact
ttcttcctggaagatgacccagaagatattaaccagacaagcccacgacgccgttctcgt
cgtggcactttgtcttctatatcttctctcaaaagtgaggacctggacaaccttaacttg
gatcacttacattttacacctgaatctatacgcttcaaagaaaaatgtgtcatgaacaac
tacttcggaattggactggatgctaaaatttctctggacttcaacaccagaagagatgaa
cacccagggcaatacaatagccgccttaagaacaagatgtggtatggccttctgggaacc
aaagaacttttgcagcgctcttacaggaaactggaagaacgagtgcatttggagtgtgat
ggagaaaccatctccttgccaaacctgcaaggcattgtagtgctcaacattaccagctat
gctggaggtatcaacttctggggaagcaacacagcaaccacggaatatgaggctcctgca
atcgatgatgggaaactggaggtggtggcaatctttggttctgtgcagatggcaatgtcc
cgtatcatcaacctgcatcatcatcgcattgcccagtgccatgaggtgatgataaccatt
gatggtgaagaaggtatcccagtgcaggtggatggggaggcctggattcagagaccaggc
cttatcaaaattagatacaagaacgctgcccagatgctgacaagagatcgggactttgag
aactcaatgaaaatgtgggaatacaagcatactgaaattcaagctgcccctcaaccccag
ctggacttccaggactctcaagagagcctctctgacgaggagtatgcccagatgcagcac
ttagctcggcttgcagaaaacctcatcagcaaacttaatgacctgagcaagatccaccag
catgtgtctgtcctcatgggttctgtgaatgccagcgctaacatcctgaatgatatattt
tacggccaagacagtggcaatgagatgggtgcagcttcctgtattcccattgaaactcta
agcagaaatgatgccgtagatgttacatttagtcttaaaggtctctacgatgacaccaca
gctttcctggatgaaaagctgctgagaagtgctgaggatgagactgcactacaaagcgcc
ctggatgccatgaataaggagttcaaaaagctatctgagattgactggatgaatccaatc
tttgttccagaggaaaaatcttcggacactgacagtagaagcctcaggctgaaaattaag
ttccccaaattgggaaagaaaaaggtagaagaggaacgcaagcctaaatcaggccagagt
gtccagagttttattggcaatttatggcaccgcagacatcgtgaagatgaagcagagggt
gatgatcctctaacaccatcgagatctcaactgtag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (6)   
Disease (1)   
   OMIM (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (62)   
   KEGG ORTHOLOGY (1)   
   RefGene (56)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (11)   
   RefSeq(nuc) (1)   
   GenBank (5)   
   EMBL (5)   
Protein domain (7)   
   Pfam (7)   
All databases (99)   

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