KEGG   Homo sapiens (human): 139818
Entry
139818            CDS       T01001                                 
Symbol
DOCK11, ACG, ADMIDX, ZIZ2, bB128O4.1
Name
(RefSeq) dedicator of cytokinesis 11
  KO
K21853  dedicator of cytokinesis protein 9/10/11
Organism
hsa  Homo sapiens (human)
Disease
H02656  X-linked multisystem autoinflammatory disease with immune dysregulation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    139818 (DOCK11)
Membrane trafficking [BR:hsa04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    139818 (DOCK11)
SSDB
Motif
Pfam: DHR-2_Lobe_A DOCK-C2 DOCK_C-D_N DHR-2_Lobe_C DHR-2_Lobe_B PH
Other DBs
NCBI-GeneID: 139818
NCBI-ProteinID: NP_653259
OMIM: 300681
HGNC: 23483
Ensembl: ENSG00000147251
UniProt: Q5JSL3
Position
X:118495815..118686147
AA seq 2073 aa
MAEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKVVEPLDYENVIAQRKTQIYSDP
LRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYE
DFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNST
ITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAF
ELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKA
ENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFE
EKCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLN
PPSVREMLWGSSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVAR
IEKVLQGNITHCAEPYIKNSDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDTQG
SLDLDGRFSPLYKQDSSKLSSEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDLSNC
ITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAK
ARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPI
HLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITFEQQLPVSAN
LPPGYLNLNDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQS
GSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIV
SKCHEEGLDSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLSINKLLKY
SWFFFEIIAKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDES
RNVNYSLASFLKRCLTLMDRGFIFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYI
PLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISV
IKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRD
EFPCGFTSPANRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGNTGENTR
QSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVC
LFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLN
HSSTTTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKTQLLNNDGHNPLMKKVFDIH
LAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNE
ASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANS
DRPMKATAFPAEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKT
WLDSMAKIHVKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNGCSAFKKITPNIDEEGAMK
EDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEKRREFEKLTQVYR
TLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLV
KLYGEKFGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNI
SRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPIDVATD
EIKDKTAELQKLCSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPPKKV
SELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRDMVKELSDIIHEQILQEDT
MHSPWMSNTLHVFCAISGTSSDRGYGSPRYAEV
NT seq 6222 nt   +upstreamnt  +downstreamnt
atggccgaagtgcgcaaattcaccaaacggctcagcaagcctggcacggcggctgagctc
cggcagagcgtgtctgaggccgtgcggggctccgtggtgctggaaaaggccaaagttgtt
gagcccctggactatgagaatgttattgcccaaagaaaaacccagatttacagcgacccc
ctccgagatctgcttatgttcccaatggaagatatatctatctcggtgataggtcgtcaa
cgcagaacggtgcagtctactgtaccagaagatgctgaaaagagggcccagagtttattt
gttaaagagtgtattaaaacctatagcacagattggcacgtggtaaactacaagtatgag
gacttctctggggactttcgaatgttgccatgtaaatctttgagaccagaaaagattcct
aatcatgtatttgagatagatgaagactgtgagaaagatgaggactcatcttctttatgt
tctcagaagggtggtgtgataaaacaaggctggttgcataaagcaaatgtaaatagtacc
atcacagtaaccatgaaggtattcaagagacgatatttttacttgacccaacttcctgac
ggttcatatattctcaattcctataaagatgagaaaaattcaaaagaatcgaaaggttgc
atctacttggacgcctgcattgatgttgttcagtgccccaaaatgcgccgtcatgctttt
gaactcaagatgttagataaatatagccattatctggctgctgaaactgagcaggaaatg
gaggaatggttgataactttgaaaaagattattcagatcaacaccgacagtttagttcaa
gaaaaaaaggagacggtagaaacagcacaagatgatgaaactagcagccaaggaaaagcc
gagaacatcatggcaagtttggaaaggagcatgcatccggaactgatgaagtatggaaga
gaaactgaacaactaaacaaactcagtagaggagatggaagacagaatctcttttctttt
gattcagaagttcagaggttggacttttcaggaattgaacctgatataaagccatttgaa
gaaaaatgcaataaacgtttcctggtgaattgccatgatttaactttcaatatcttgggc
caaattggagacaatgcaaaaggaccacccacaaatgttgagcccttttttatcaatctt
gccttatttgatgtaaagaacaattgtaagatttcagcagactttcatgtagacctgaat
cccccatctgtccgtgaaatgctgtggggctcttcaacccaactggccagtgacggtagc
ccaaagggctcttcacccgaatcttacattcatggaattgccgaatctcagttacgctac
atacaacagggaattttctcagtgacgaatccacatcctgaaatttttctagttgccaga
attgaaaaggtactacagggaaacattacacactgtgcagaaccctatatcaaaaattct
gatccagtaaagacggcccagaaggtgcacaggacagctaaacaagtgtgtagccgcctt
ggacaatacagaatgcccttcgcttgggctgccagacccattttcaaagatactcaaggc
tctcttgatctggatgggagattttctcctctgtataaacaagacagtagcaagctttca
agtgaagacattctcaagttgctctcagaatataagaagccagaaaagaccaaactgcag
attattcctgggcagctaaacatcacagtagaatgtgttcctgtggatttatcaaattgt
attacttcttcatatgtgcccttgaagccttttgaaaagaattgccaaaatattactgtg
gaggttgaagagtttgttccagaaatgacaaaatattgttatccatttactatttacaaa
aaccatctgtatgtatatcccctgcaattaaaatacgatagccagaaaacatttgccaag
gcaaggaacattgcagtctgtgtggaattccgggattcagatgaaagtgacgctagtgcc
ctaaagtgtatttatggaaaacctgcagggtctgtttttaccacaaatgcttatgctgtt
gtctcgcatcacaaccaaaatccagagttctatgatgagattaaaattgagcttcccatt
cacctacatcaaaaacatcatttgcttttcactttttatcatgtaagttgtgaaattaac
acaaagggaacaaccaaaaagcaagacacagttgaaactccagttgggtttgcctgggta
cctttgctgaaagatggtagaatcatcacatttgagcagcagctgccagtttccgccaat
cttcccccaggctacttgaatctgaatgatgcagaatcaagaaggcaatgtaacgtggat
attaaatgggtagatggtgcaaagcctttgttgaagattaaaagccacttagaatctacc
atttacactcaagatctgcatgtgcacaaattcttccatcattgccagctgattcagtca
ggctcgaaagaagttccaggggagctcattaaatatttaaagtgtttgcatgccatggag
atccaagtcatgatacagtttctacctgtaattcttatgcaactcttccgagttctcaca
aatatgacccatgaagatgacgttcctatcaactgcaccatggttctcttacatattgta
tcaaagtgccatgaagaaggcttggatagttatctaagatcattcataaagtatagcttc
cgacctgaaaaaccgagtgctcctcaggcccagctgatacatgaaaccctggctactacg
atgatagcaatattgaaacagtctgcagattttttatcaataaacaaattgctaaagtac
tcatggtttttctttgaaataattgcaaagtcaatggccacatacttgttggaagagaat
aagattaagcttccccgaggccagagatttcccgagacatatcatcatgtcttacattca
ctgcttcttgcaataattccccatgtgactattcggtatgcggagattcccgatgagtcc
agaaatgtgaactatagtttggctagcttcctgaagcgctgtttgacactaatggataga
ggatttattttcaatttaataaatgactatatatctggattcagccccaaagatcctaag
gttctggctgaatacaagtttgaatttctgcaaacaatttgcaatcacgaacattacatt
cctctgaacttgccaatggcatttgcaaaacctaaactgcagcgggttcaagattcaaat
cttgaatacagtttatcagatgagtattgcaagcatcacttcttggttggtctacttctg
agggaaacttccattgctcttcaggacaattatgagatcagatatacagctatctctgtt
ataaagaatcttttgataaaacatgcatttgacacaagataccagcacaagaaccaacaa
gccaaaatagcacaattgtacctcccctttgttggactacttttggaaaatatacagcga
ttagcaggtcgagataccttgtattcttgtgcagccatgcctaattctgcatccagagat
gagtttccatgtggctttacttcacctgccaatagagggagtctgagcactgacaaagac
accgcttatgggtcttttcaaaatggacatggaattaagagagaagattcaagaggttcc
ctcatcccagaaggagcaacaggatttccagatcagggcaacactggtgaaaatacccga
cagagttctacaaggagtagtgtatcccagtataaccgcctggatcagtatgaaatcaga
agcctcctgatgtgctacctgtatatagtaaaaatgatttcagaagatactctcttaact
tactggaataaagtatcacctcaggagctcataaacattcttatacttttagaagtatgc
ttgtttcactttagatatatggggaaaagaaacatagcaagggtgcatgatgcctggctg
tcaaaacacttcggaatagaccgaaaatcgcaaaccatgcctgctcttcgaaacagatca
ggagtaatgcaggcccggcttcagcatcttagtagcctagaaagttcatttacacttaat
cacagttctacaacaactgaagcagacattttccaccaggcacttcttgaaggcaataca
gctactgaagtttccctaacagtactagacaccatatcatttttcactcagtgcttcaag
acccaacttttaaataatgatggccataacccattaatgaaaaaagtgtttgatatacat
cttgcttttcttaaaaatggacaatctgaagtgtcgctgaaacatgtatttgcctcactg
agagctttcatcagtaagtttccttcagcatttttcaaaggaagagtaaacatgtgtgct
gcattttgctatgaggttttaaagtgctgcacatcgaagattagctcaaccaggaatgaa
gcatctgcacttttgtatcttttgatgagaaacaactttgagtataccaaaaggaaaacc
tttttgaggacacatctacagataataattgctgtaagccaactgatagctgatgtagca
ctaagcggaggatcaagatttcaggagtctttattcattatcaataattttgcaaatagt
gacagacctatgaaggcaactgcctttcccgcagaagtcaaagacttgaccaagagaatc
cgcactgttcttatggccactgcccaaatgaaggagcatgagaaagaccctgaaatgcta
attgatctccagtatagcttagccaagtcctatgcaagcaccccagagctcaggaaaacc
tggcttgatagcatggccaagattcatgtaaaaaatggagatttttcagaggctgcgatg
tgttatgtccatgtagcagctctagttgcagagtttcttcatcgaaaaaaattatttcct
aacggatgttcagcgttcaagaaaattactcccaatatagatgaagaaggagcaatgaaa
gaagatgctgggatgatggatgtccattatagtgaagaggtcttgctggagttgctagaa
caatgtgtggatggcttatggaaggcagaacgttatgaaataatttctgagatttccaag
ttgatcgttccaatttatgagaaacgtcgtgagtttgagaaacttactcaagtttataga
actcttcatggagcttacacaaaaattctggaagttatgcatacaaaaaagagactttta
ggcactttcttcagagttgccttttatggccaatctttttttgaagaagaagatggaaag
gagtacatctataaagaaccaaagctcactggcctctcagaaatttccttgagacttgtt
aaactttatggtgaaaagtttggtacggagaatgtcaaaataattcaggattcagacaag
gtaaatgccaaagagcttgatccaaaatatgctcatatacaagttacttatgtgaagcct
tactttgatgacaaagaactcacagaaaggaagaccgagtttgaaagaaatcataatatc
agcagatttgtttttgaggccccttacactttatcaggcaaaaaacagggctgtatagaa
gaacagtgcaaacgccgtacaatcttgacaacttcaaactcgtttccttacgtgaagaag
aggattcctattaactgtgaacagcagattaatttaaaaccaattgatgttgccactgat
gaaataaaagataaaactgcagagctgcaaaagctttgctcctctactgacgtggacatg
attcagctccaacttaaattgcagggctgtgtttctgtgcaggtcaatgctggtccatta
gcatatgcaagagctttcttaaatgacagccaagctagcaagtatccacctaagaaagtg
agtgagttgaaagacatgtttaggaaatttatacaagcatgcagcattgcacttgaacta
aatgagcggctaattaaagaagatcaagttgagtaccatgaagggctaaagtcaaatttc
agagacatggtaaaagaattatctgacattatccatgagcagatattacaagaagacaca
atgcattctccctggatgagcaacacattacatgtattttgtgcaattagtggtacatca
agtgaccgaggttatggttccccaagatacgctgaagtgtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (13)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (37)   
   RefSeq(nuc) (11)   
   GenBank (13)   
   EMBL (13)   
Protein domain (6)   
   Pfam (6)   
All databases (83)   

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