| Entry |
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| Symbol |
CSNK2A1, CK2A1, CKII, Cka1, Cka2, OCNDS
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| Name |
(RefSeq) casein kinase 2 alpha 1
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| KO |
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| Organism |
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| Pathway |
| hsa03008 | Ribosome biogenesis in eukaryotes |
| hsa05022 | Pathways of neurodegeneration - multiple diseases |
| hsa05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer |
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| Network |
nt06465 Prion disease nt06466 Pathways of neurodegeneration nt06512 Chromosome cohesion and segregation nt06523 Epigenetic regulation by Polycomb complexes |
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| Element |
| N01202 | Oligomeric conformation PrPc to anterograde axonal transport |
| N01501 | Inactivation of condensin I |
| N01620 | Blocking ubiquitination of H2AK119 by CK2 |
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| Disease |
| H02460 | Neurodevelopmental disorder with dysmorphic facies and skeletal anomalies |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09120 Genetic Information Processing
09122 Translation
03008 Ribosome biogenesis in eukaryotes
1457 (CSNK2A1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
1457 (CSNK2A1)
04064 NF-kappa B signaling pathway
1457 (CSNK2A1)
09140 Cellular Processes
09141 Transport and catabolism
04137 Mitophagy - animal
1457 (CSNK2A1)
09144 Cellular community - eukaryotes
04520 Adherens junction
1457 (CSNK2A1)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
1457 (CSNK2A1)
09172 Infectious disease: viral
05162 Measles
1457 (CSNK2A1)
09164 Neurodegenerative disease
05010 Alzheimer disease
1457 (CSNK2A1)
05020 Prion disease
1457 (CSNK2A1)
05022 Pathways of neurodegeneration - multiple diseases
1457 (CSNK2A1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:hsa01001]
1457 (CSNK2A1)
09182 Protein families: genetic information processing
03009 Ribosome biogenesis [BR:hsa03009]
1457 (CSNK2A1)
Enzymes [BR:hsa01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
1457 (CSNK2A1)
Protein kinases [BR:hsa01001]
Serine/threonine kinases: Other
CK2 family
1457 (CSNK2A1)
Ribosome biogenesis [BR:hsa03009]
Eukaryotic type
90S particles
Kinase
1457 (CSNK2A1)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| Position |
20:complement(472498..543790)
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| AA seq |
391 aa
MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT
NNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTD
FKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE
FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYD
QLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDF
LDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPT
PSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ |
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| NT seq |
1176 nt +upstreamnt +downstreamnt
atgtcgggacccgtgccaagcagggccagagtttacacagatgttaatacacacagacct
cgagaatactgggattacgagtcacatgtggtggaatggggaaatcaagatgactaccag
ctggttcgaaaattaggccgaggtaaatacagtgaagtatttgaagccatcaacatcaca
aataatgaaaaagttgttgttaaaattctcaagccagtaaaaaagaagaaaattaagcgt
gaaataaagattttggagaatttgagaggaggtcccaacatcatcacactggcagacatt
gtaaaagaccctgtgtcacgaacccccgccttggtttttgaacacgtaaacaacacagac
ttcaagcaattgtaccagacgttaacagactatgatattcgattttacatgtatgagatt
ctgaaggccctggattattgtcacagcatgggaattatgcacagagatgtcaagccccat
aatgtcatgattgatcatgagcacagaaagctacgactaatagactggggtttggctgag
ttttatcatcctggccaagaatataatgtccgagttgcttcccgatacttcaaaggtcct
gagctacttgtagactatcagatgtacgattatagtttggatatgtggagtttgggttgt
atgctggcaagtatgatctttcggaaggagccatttttccatggacatgacaattatgat
cagttggtgaggatagccaaggttctggggacagaagatttatatgactatattgacaaa
tacaacattgaattagatccacgtttcaatgatatcttgggcagacactctcgaaagcga
tgggaacgctttgtccacagtgaaaatcagcaccttgtcagccctgaggccttggatttc
ctggacaaactgctgcgatatgaccaccagtcacggcttactgcaagagaggcaatggag
cacccctatttctacactgttgtgaaggaccaggctcgaatgggttcatctagcatgcca
gggggcagtacgcccgtcagcagcgccaatatgatgtcagggatttcttcagtgccaacc
ccttcaccccttggacctctggcaggctcaccagtgattgctgctgccaacccccttggg
atgcctgttccagctgccgctggcgctcagcagtaa |
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