KEGG   Homo sapiens (human): 147746
Entry
147746            CDS       T01001                                 
Symbol
HIPK4
Name
(RefSeq) homeodomain interacting protein kinase 4
  KO
K08826  homeodomain interacting protein kinase [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04218  Cellular senescence
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    147746 (HIPK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    147746 (HIPK4)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     147746 (HIPK4)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CMGC group
  DYRK family [OT]
   147746 (HIPK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH TCAD9 Kdo Kinase-like Pox_ser-thr_kin
Other DBs
NCBI-GeneID: 147746
NCBI-ProteinID: NP_653286
OMIM: 611712
HGNC: 19007
Ensembl: ENSG00000160396
UniProt: Q8NE63 A0A140VJL1
Position
19:complement(40379271..40390181)
AA seq 616 aa
MSTIQSETDCYDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKNDAYRNRIIKNELKLLH
CMRGLDPEEAHVIRFLEFFHDALKFYLVFELLEQNLFEFQKENNFAPLPARHIRTVTLQV
LTALARLKELAIIHADLKPENIMLVDQTRCPFRVKVIDFGSASIFSEVRYVKEPYIQSRF
YRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICETQGLPKPHLLH
AACKAHHFFKRNPHPDAANPWQLKSSADYLAETKVRPLERRKYMLKSLDQIETVNGGSVA
SRLTFPDREALAEHADLKSMVELIKRMLTWESHERISPSAALRHPFVSMQQLRSAHETTH
YYQLSLRSYRLSLQVEGKPPTPVVAAEDGTPYYCLAEEKEAAGMGSVAGSSPFFREEKAP
GMQRAIDQLDDLSLQEAGHGLWGETCTNAVSDMMVPLKAAITGHHVPDSGPEPILAFYSS
RLAGRHKARKPPAGSKSDSNFSNLIRLSQVSPEDDRPCRGSSWEEGEHLGASAEPLAILQ
RDEDGPNIDNMTMEAERPDPELFDPSSCPGEWLSEPDCTLESVRGPRAQGLPPRRSHQHG
PPRGATSFLQHVTGHH
NT seq 1851 nt   +upstreamnt  +downstreamnt
atgtccaccatccagtcggagactgactgctacgacatcatcgaggtcttgggcaagggg
accttcggggaggtagccaagggctggcggcggagcacgggcgagatggtggccatcaag
atcctcaagaatgacgcctaccgcaaccgcatcatcaagaacgagctgaagctgctgcac
tgcatgcgaggcctagaccctgaagaggcccacgtcatccgcttccttgagttcttccat
gacgccctcaagttctacctggtctttgagctgctggagcaaaaccttttcgagttccag
aaggagaacaacttcgcgcccctccccgcccgccacatccgtacagtcaccctgcaggtg
ctcacagccctggcccggctcaaggagctggctatcatccacgctgatctcaagcctgag
aacatcatgctggtggaccagacccgctgccccttcagggtcaaggtgattgacttcgga
tccgccagcattttcagcgaggtgcgctacgtgaaggagccatacatccagtcgcgcttc
taccgggcccctgagatcctgctggggctgcccttctgcgagaaggtggacgtgtggtcc
ctgggctgcgtcatggctgagctgcacctgggctggcctctctaccccggcaacaacgag
tacgaccaggtgcgctacatctgcgaaacccagggcctgcccaagccacacctgttgcac
gccgcctgcaaggcccaccacttcttcaagcgcaacccccaccctgacgctgccaacccc
tggcagctcaagtcctcggctgactacctggccgagacgaaggtgcgcccattggagcgc
cgcaagtatatgctcaagtcgttggaccagattgagacagtgaatggtggcagtgtggcc
agtcggctaaccttccctgaccgggaggcgctggcggagcacgccgacctcaagagcatg
gtggagctgatcaagcgcatgctgacctgggagtcacacgaacgcatcagccccagtgct
gccctgcgccaccccttcgtgtccatgcagcagctgcgcagtgcccacgagaccacccac
tactaccagctctcgctgcgcagctaccgcctctcgctgcaagtggaggggaagcccccc
acgcccgtcgtggccgcagaagatgggaccccctactactgtctggctgaggagaaggag
gctgcgggtatgggcagtgtggccggcagcagccccttcttccgagaggagaaggcacca
ggtatgcaaagagccatcgaccagctggatgacctgagtctgcaggaggctgggcatggg
ctgtggggtgagacctgcaccaatgcggtctccgacatgatggtccccctcaaggcagcc
atcactggccaccatgtgcccgactcgggccctgagcccatcctggccttctacagcagc
cgcctggcaggccgccacaaggcccgcaagccacctgcgggttccaagtccgactccaac
ttcagcaacctcattcggctgagccaggtctcgcctgaggatgacaggccctgccggggc
agcagctgggaggaaggagagcatctcggggcctctgctgagccactggccatcctgcag
cgagatgaggatgggcccaacattgacaacatgaccatggaagctgagaggccagaccct
gagctcttcgaccccagcagctgtcctggagaatggctgagtgagccagactgcaccctg
gagagcgtcaggggcccacgggctcaggggctcccaccccgccgctcccaccagcatggt
ccaccccggggggccaccagcttcctccagcatgtcaccgggcaccactga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (15)   
   RefSeq(nuc) (1)   
   GenBank (7)   
   EMBL (7)   
Protein domain (7)   
   Pfam (7)   
All databases (51)   

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