KEGG   Homo sapiens (human): 147945
Entry
147945            CDS       T01001                                 
Symbol
NLRP4, CLR19.5, CT58, NALP4, PAN2, PYPAF4, RNH2
Name
(RefSeq) NLR family pyrin domain containing 4
  KO
K22265  NACHT, LRR and PYD domains-containing protein 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa05130  Pathogenic Escherichia coli infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    147945 (NLRP4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    147945 (NLRP4)
  09183 Protein families: signaling and cellular processes
   04054 Pattern recognition receptors [BR:hsa04054]
    147945 (NLRP4)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Other autophagy associated proteins
   Others
    147945 (NLRP4)
Pattern recognition receptors [BR:hsa04054]
 Cytoplasmic pattern recognition receptors
  NOD-like receptors
   147945 (NLRP4)
SSDB
Motif
Pfam: NACHT PYRIN NLRC4_HD2 NOD2_WH LRR_6 AAA_16 nSTAND3 VapE-like_dom AAA_22 AAA_14 ResIII DAP3 RNA_helicase AAA_25 AAA_30 LRR_4
Other DBs
NCBI-GeneID: 147945
NCBI-ProteinID: NP_604393
OMIM: 609645
HGNC: 22943
Ensembl: ENSG00000160505
UniProt: Q96MN2 B2RCA1
Structure
Position
19:55836540..55881855
AA seq 994 aa
MAASFFSDFGLMWYLEELKKEEFRKFKEHLKQMTLQLELKQIPWTEVKKASREELANLLI
KHYEEQQAWNITLRIFQKMDRKDLCMKVMRERTGYTKTYQAHAKQKFSRLWSSKSVTEIH
LYFEEEVKQEECDHLDRLFAPKEAGKQPRTVIIQGPQGIGKTTLLMKLMMAWSDNKIFRD
RFLYTFYFCCRELRELPPTSLADLISREWPDPAAPITEIVSQPERLLFVIDSFEELQGGL
NEPDSDLCGDLMEKRPVQVLLSSLLRKKMLPEASLLIAIKPVCPKELRDQVTISEIYQPR
GFNESDRLVYFCCFFKDPKRAMEAFNLVRESEQLFSICQIPLLCWILCTSLKQEMQKGKD
LALTCQSTTSVYSSFVFNLFTPEGAEGPTPQTQHQLKALCSLAAEGMWTDTFEFCEDDLR
RNGVVDADIPALLGTKILLKYGERESSYVFLHVCIQEFCAALFYLLKSHLDHPHPAVRCV
QELLVANFEKARRAHWIFLGCFLTGLLNKKEQEKLDAFFGFQLSQEIKQQIHQCLKSLGE
RGNPQGQVDSLAIFYCLFEMQDPAFVKQAVNLLQEANFHIIDNVDLVVSAYCLKYCSSLR
KLCFSVQNVFKKEDEHSSTSDYSLICWHHICSVLTTSGHLRELQVQDSTLSESTFVTWCN
QLRHPSCRLQKLGINNVSFSGQSVLLFEVLFYQPDLKYLSFTLTKLSRDDIRSLCDALNY
PAGNVKELALVNCHLSPIDCEVLAGLLTNNKKLTYLNVSCNQLDTGVPLLCEALCSPDTV
LVYLMLAFCHLSEQCCEYISEMLLRNKSVRYLDLSANVLKDEGLKTLCEALKHPDCCLDS
LCLVKCFITAAGCEDLASALISNQNLKILQIGCNEIGDVGVQLLCRALTHTDCRLEILGL
EECGLTSTCCKDLASVLTCSKTLQQLNLTLNTLDHTGVVVLCEALRHPECALQVLGLRKT
DFDEETQALLTAEEERNPNLTITDDCDTITRVEI
NT seq 2985 nt   +upstreamnt  +downstreamnt
atggcagcctctttcttctctgattttggtcttatgtggtatctggaggagctcaaaaag
gaggagttcaggaaatttaaagaacatctcaagcaaatgactttgcagcttgaactcaag
cagattccctggactgaggtcaaaaaagcatcccgggaagaacttgcaaacctcttgatc
aagcactatgaagaacaacaagcttggaacataaccttaagaatctttcaaaagatggat
agaaaggatctctgcatgaaggtcatgagggagagaacaggatacacaaagacctatcaa
gctcacgcaaagcagaaattcagccgcttatggtccagcaagtctgtcactgagattcac
ctatactttgaggaggaagtcaagcaagaagaatgtgaccatttggaccgcctttttgct
cccaaggaagctgggaaacagccacgtacagtgatcattcaaggaccacaaggaattgga
aaaacgacactcctgatgaagctgatgatggcctggtcggacaacaagatctttcgggat
aggttcctgtacacgttctatttctgctgcagagaactgagggagttgccgccaacgagt
ttggctgacttgatttccagagagtggcctgaccccgctgctcctataacagagatcgtg
tctcaaccggagagactcttgttcgtcatcgacagcttcgaagagctgcagggcggcttg
aacgaacccgattcggatctgtgtggtgacttgatggagaaacggccggtgcaggtgctt
ctgagcagtttgctgaggaagaagatgctcccggaggcctccctgctcatcgctatcaaa
cccgtgtgcccgaaggagctccgggatcaggtgacgatctcagaaatctaccagccccgg
ggattcaacgagagtgataggttagtgtatttctgctgtttcttcaaagacccgaaaaga
gccatggaagccttcaatcttgtaagagaaagtgaacagctgttttccatatgccaaatc
ccgctcctctgctggatcctgtgtaccagtctgaagcaagagatgcagaaaggaaaagac
ctggccctgacctgccagagcactacctctgtgtactcctctttcgtctttaacctgttc
acacctgagggtgccgagggcccgactccgcaaacccagcaccagctgaaggccctgtgc
tccctggctgcagagggtatgtggacagacacatttgagttttgtgaagacgacctccgg
agaaatggggttgttgacgctgacatccctgcgctgctgggcaccaagatacttctgaag
tacggggagcgtgagagctcctacgtgttcctccacgtgtgtatccaggagttctgtgcc
gccttgttctatttgctcaagagccaccttgatcatcctcacccagctgtgagatgtgta
caggaattgctagttgccaattttgaaaaagcaaggagagcacattggatttttttgggg
tgttttctaactggccttttaaataaaaaggaacaagaaaaactggatgcgttttttggc
ttccaactgtcccaagagataaagcagcaaattcaccagtgcctgaagagcttaggggag
cgtggcaatcctcagggacaggtggattccttggcgatattttactgtctctttgaaatg
caggatcctgcctttgtgaagcaggcagtgaacctcctccaagaagctaactttcatatt
attgacaacgtggacttggtggtttctgcctactgcttaaaatactgctccagcttgagg
aaactctgtttttccgttcaaaatgtctttaagaaagaggatgaacacagctctacgtcg
gattacagcctcatctgttggcatcacatctgctctgtgctcaccaccagcgggcacctc
agagagctccaggtgcaggacagcaccctcagcgagtcgacctttgtgacctggtgtaac
cagctgaggcatcccagctgtcgccttcagaagcttggaataaataacgtttccttttct
ggccagagtgttctgctctttgaggtgctcttttatcagccagacttgaaatacctgagc
ttcaccctcacgaaactctctcgtgatgacatcaggtccctctgtgatgccttgaactac
ccagcaggcaacgtcaaagagctagcgctggtaaattgtcacctctcacccattgattgt
gaagtccttgctggccttctaaccaacaacaagaagctgacgtatctgaatgtatcctgc
aaccagttagacacaggcgtgccccttttgtgtgaagccctgtgcagcccagacacggtc
ctggtatacctgatgttggctttctgccacctcagcgagcagtgctgcgaatacatctct
gaaatgcttctgcgtaacaagagcgtgcgctatctagacctcagtgccaatgtcctgaag
gacgaaggactgaaaactctctgcgaggccttgaaacatccggactgctgcctggattca
ctgtgtttggtaaaatgttttatcactgctgctggctgtgaagacctcgcctctgctctc
atcagcaatcaaaacctgaagattctgcaaattgggtgcaatgaaatcggagatgtgggt
gtgcagctgttgtgtcgggctctgacgcatacggattgccgcttagagattcttgggttg
gaagaatgtgggttaacgagcacctgctgtaaggatctcgcgtctgttctcacctgcagt
aagaccctgcagcagctcaacctgaccttgaacaccttggaccacacaggggtggttgta
ctctgtgaggccctgagacacccagagtgtgccctgcaggtgctcgggctgagaaaaact
gattttgatgaggaaacccaggcacttctgacggctgaggaagagagaaatcctaacctg
accatcacagacgactgtgacacaatcacaagggtagagatctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (37)   
   KEGG ORTHOLOGY (1)   
   RefGene (29)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (29)   
   RefSeq(nuc) (5)   
   GenBank (12)   
   EMBL (12)   
3D Structure (1)   
   PDB (1)   
Protein domain (16)   
   Pfam (16)   
All databases (97)   

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