KEGG   Homo sapiens (human): 1488
Entry
1488              CDS       T01001                                 
Symbol
CTBP2
Name
(RefSeq) C-terminal binding protein 2
  KO
K04496  C-terminal binding protein [EC:1.1.1.428]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04310  Wnt signaling pathway
hsa04330  Notch signaling pathway
hsa05200  Pathways in cancer
hsa05220  Chronic myeloid leukemia
Network
nt06523  Epigenetic regulation by Polycomb complexes
  Element
N01577  Gene silencing by methylation of H3K27 and ubiquitination of H2AK119
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    1488 (CTBP2)
   04330 Notch signaling pathway
    1488 (CTBP2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    1488 (CTBP2)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    1488 (CTBP2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    1488 (CTBP2)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.428  4-methylthio 2-oxobutanoate reductase (NADH)
     1488 (CTBP2)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Macropinocytosis
   Others
    1488 (CTBP2)
SSDB
Motif
Pfam: 2-Hacid_dh_C 2-Hacid_dh NAD_binding_2
Other DBs
NCBI-GeneID: 1488
NCBI-ProteinID: NP_001077383
OMIM: 602619
HGNC: 2495
Ensembl: ENSG00000175029
UniProt: P56545
Structure
Position
10:complement(124984317..125162463)
AA seq 445 aa
MALVDKHKVKRQRLDRICEGIRPQIMNGPLHPRPLVALLDGRDCTVEMPILKDLATVAFC
DAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELG
IAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRG
ETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVS
LHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHES
EPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESLRNCVNKE
FFVTSAPWSVIDQQAIHPELNGATYRYPPGIVGVAPGGLPAAMEGIIPGGIPVTHNLPTV
AHPSQAPSPNQPTKHGDNREHPNEQ
NT seq 1338 nt   +upstreamnt  +downstreamnt
atggcccttgtggataagcacaaagtcaagagacagcgattggacagaatttgtgaaggt
atccgcccccagatcatgaacggccccctgcacccccgccccctggtggcgctgctggac
ggccgcgactgcactgtggagatgcccatcctgaaggacctggccactgtggccttctgt
gacgcgcagtcgacgcaggaaatccacgagaaggttctaaacgaagccgtgggcgccatg
atgtaccacaccatcaccctcaccagggaggacctggagaagttcaaggccctgagagtg
atcgtgcggataggcagtggctatgacaacgtggacatcaaggctgccggcgagctcgga
attgccgtgtgcaacatcccgtctgcagccgtggaagagacagcggactctaccatctgc
cacatcctcaacctgtaccggaggaacacgtggctgtaccaggcactgcgggaaggcacg
cgggttcagagcgtggagcagatccgcgaggtggcctcgggagcggcccgcatccgtggg
gagacgctgggcctcattggctttggtcgcacggggcaggcggttgcagttcgagccaag
gcctttggattcagcgtcatattttatgacccctacttgcaggatgggatcgagcggtcc
ctgggcgtgcagagggtctacaccctgcaggatttgctgtatcagagcgactgcgtctcc
ttgcactgcaatctcaacgaacataaccaccacctcatcaatgactttaccataaagcag
atgaggcagggagcattccttgtgaacgcagcccgtggcggcctggtggacgagaaagcc
ttagcacaagccctcaaggagggcaggatacgaggggcagccctcgacgtgcatgagtca
gagcccttcagctttgctcagggtccgttgaaagatgccccgaatctcatctgcactcct
cacactgcctggtacagtgagcaggcgtcactggagatgagggaggcagctgccaccgag
atccgccgagccatcacaggtcgcatcccagaaagcttaagaaattgtgtgaacaaggaa
ttctttgtcacatcagcgccttggtcagtaatagaccagcaagcaattcatcctgagctc
aatggtgccacatacagatatccgccaggcatcgtgggtgtggctccaggaggacttcct
gcagccatggaagggatcatccctggaggcatcccagtgactcacaacctcccgacagtg
gcacatccttcccaagcgccctctcccaaccagcccacaaaacacggggacaatcgagag
caccccaacgagcaatag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
Protein sequence (32)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (30)   
DNA sequence (80)   
   RefSeq(nuc) (30)   
   GenBank (25)   
   EMBL (25)   
3D Structure (3)   
   PDB (3)   
Protein domain (3)   
   Pfam (3)   
All databases (145)   

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