KEGG   Homo sapiens (human): 1490
Entry
1490              CDS       T01001                                 
Symbol
CCN2, CTGF, HCS24, IBP-8, IGFBP8, NOV2
Name
(RefSeq) cellular communication network factor 2
  KO
K06827  connective tissue growth factor (insulin-like growth factor-binding protein 8)
Organism
hsa  Homo sapiens (human)
Pathway
hsa04371  Apelin signaling pathway
hsa04390  Hippo signaling pathway
Drug target
Pamrevlumab: D10969
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    1490 (CCN2)
   04371 Apelin signaling pathway
    1490 (CCN2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    1490 (CCN2)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Others
   Insulin-like growth factor-binding proteins
    1490 (CCN2)
SSDB
Motif
Pfam: TSP1_CCN Cys_knot IGFBP VWC TSP_1
Other DBs
NCBI-GeneID: 1490
NCBI-ProteinID: NP_001892
OMIM: 121009
HGNC: 2500
Ensembl: ENSG00000118523
UniProt: P29279 Q5M8T4
Position
6:complement(131948176..131951372)
AA seq 349 aa
MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVC
AKQLGELCTERDPCDPHKGLFCHFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSC
KYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTVVGPALA
AYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVR
PCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTT
LPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDMA
NT seq 1050 nt   +upstreamnt  +downstreamnt
atgaccgccgccagtatgggccccgtccgcgtcgccttcgtggtcctcctcgccctctgc
agccggccggccgtcggccagaactgcagcgggccgtgccggtgcccggacgagccggcg
ccgcgctgcccggcgggcgtgagcctcgtgctggacggctgcggctgctgccgcgtctgc
gccaagcagctgggcgagctgtgcaccgagcgcgacccatgcgacccgcacaagggccta
ttctgtcacttcggctccccggccaaccgcaagatcggcgtgtgcaccgccaaagatggt
gctccctgcatcttcggtggtacggtgtaccgcagcggagagtccttccagagcagctgc
aagtaccagtgcacgtgcctggacggggcggtgggctgcatgcccctgtgcagcatggac
gttcgtctgcccagccctgactgccccttcccgaggagggtcaagctgcccgggaaatgc
tgcgaggagtgggtgtgtgacgagcccaaggaccaaaccgtggttgggcctgccctcgcg
gcttaccgactggaagacacgtttggcccagacccaactatgattagagccaactgcctg
gtccagaccacagagtggagcgcctgttccaagacctgtgggatgggcatctccacccgg
gttaccaatgacaacgcctcctgcaggctagagaagcagagccgcctgtgcatggtcagg
ccttgcgaagctgacctggaagagaacattaagaagggcaaaaagtgcatccgtactccc
aaaatctccaagcctatcaagtttgagctttctggctgcaccagcatgaagacataccga
gctaaattctgtggagtatgtaccgacggccgatgctgcaccccccacagaaccaccacc
ctgccggtggagttcaagtgccctgacggcgaggtcatgaagaagaacatgatgttcatc
aagacctgtgcctgccattacaactgtcccggagacaatgacatctttgaatcgctgtac
tacaggaagatgtacggagacatggcatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (53)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (32)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (33)   
   RefSeq(nuc) (1)   
   GenBank (16)   
   EMBL (16)   
Protein domain (5)   
   Pfam (5)   
All databases (102)   

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