KEGG   Homo sapiens (human): 150094
Entry
150094            CDS       T01001                                 
Symbol
SIK1, DEE30, MSK, SIK, SIK-1, SIK1B, SNF1LK
Name
(RefSeq) salt inducible kinase 1
  KO
K19008  serine/threonine-protein kinase SIK1 [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04922  Glucagon signaling pathway
Disease
H00606  Early infantile epileptic encephalopathy
H01819  Early myoclonic encephalopathy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    150094 (SIK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    150094 (SIK1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     150094 (SIK1)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CAMK group
  CAMKL family
   150094 (SIK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like Haspin_kinase UBA_BRSK ABC1 APH Kdo
Other DBs
NCBI-GeneID: 150094
NCBI-ProteinID: NP_775490
OMIM: 605705
HGNC: 11142
Ensembl: ENSG00000142178
UniProt: P57059
Position
21:complement(43414483..43427131)
AA seq 783 aa
MVIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDK
TRLDSSNLEKIYREVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGH
LSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEPL
STWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGR
FRIPFFMSQDCESLIRRMLVVDPARRITIAQIRQHRWMRAEPCLPGPACPAFSAHSYTSN
LGDYDEQALGIMQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRNAQCARPGPAR
QPRPRSSDLSGLEVPQEGLSTDPFRPALLCPQPQTLVQSVLQAEMDCELQSSLQWPLFFP
VDASCSGVFRPRPVSPSSLLDTAISEEARQGPGLEEEQDTQESLPSSTGRRHTLAEVSTR
LSPLTAPCIVVSPSTTASPAEGTSSDSCLTFSASKSPAGLSGTPATQGLLGACSPVRLAS
PFLGSQSATPVLQAQGGLGGAVLLPVSFQEGRRASDTSLTQGLKAFRQQLRKTTRTKGFL
GLNKIKGLARQVCQAPASRASRGGLSPFHAPAQSPGLHGGAAGSREGWSLLEEVLEQQRL
LQLQHHPAAAPGCSQAPQPAPAPFVIAPCDGPGAAPLPSTLLTSGLPLLPPPLLQTGASP
VASAAQLLDTHLHIGTGPTALPAVPPPRLARLAPGCEPLGLLQGDCEMEDLMPCSLGTFV
LVQ
NT seq 2352 nt   +upstreamnt  +downstreamnt
atggttatcatgtcggagttcagcgcggaccccgcgggccagggtcagggccagcagaag
cccctccgggtgggtttttacgacatcgagcggaccctgggcaaaggcaacttcgcggtg
gtgaagctggcgcggcatcgagtcaccaaaacgcaggttgcaataaaaataattgataaa
acacgattagattcaagcaatttggagaaaatctatcgtgaggttcagctgatgaagctt
ctgaaccatccacacatcataaagctttaccaggttatggaaacaaaggacatgctttac
atcgtcactgaatttgctaaaaatggagaaatgtttgattatttgacttccaacgggcac
ctgagtgagaacgaggcgcggaagaagttctggcaaatcctgtcggccgtggagtactgt
cacgaccatcacatcgtccaccgggacctcaagaccgagaacctcctgctggatggcaac
atggacatcaagctggcagattttggatttgggaatttctacaagtcaggagagcctctg
tccacgtggtgtgggagccccccgtatgccgccccggaagtctttgaggggaaggagtat
gaaggcccccagctggacatctggagcctgggcgtggtgctgtacgtcctggtctgcggt
tctctccccttcgatgggcctaacctgccgacgctgagacagcgggtgctggagggccgc
ttccgcatccccttcttcatgtctcaagactgtgagagcctgatccgccgcatgctggtg
gtggaccccgccaggcgcatcaccatcgcccagatccggcagcaccggtggatgcgggct
gagccctgcttgccgggacccgcctgccccgccttctccgcacacagctacacctccaac
ctgggcgactacgatgagcaggcgctgggtatcatgcagaccctgggcgtggaccggcag
aggacggtggagtcactgcaaaacagcagctataaccactttgctgccatttattacctc
ctccttgagcggctcaaggagtatcggaatgcccagtgcgcccgccccgggcctgccagg
cagccgcggcctcggagctcggacctcagtggtttggaggtgcctcaggaaggtctttcc
accgaccctttccgacctgccttgctgtgcccgcagccgcagaccttggtgcagtccgtc
ctccaggccgagatggactgtgagctccagagctcgctgcagtggcccttgttcttcccg
gtggatgccagctgcagcggagtgttccggccccggcccgtgtccccaagcagcctgctg
gacacagccatcagtgaggaggccaggcaggggccgggcctagaggaggagcaggacacg
caggagtccctgcccagcagcacgggccggaggcacaccctggccgaggtctccacccgc
ctctccccactcaccgcgccatgtatagtcgtctccccctccaccacggcaagtcctgca
gagggaaccagctctgacagttgtctgaccttctctgcgagcaaaagccccgcggggctc
agtggcaccccggccactcaggggctgctgggcgcctgctccccggtcaggctggcctcg
cccttcctggggtcgcagtccgccaccccagtgctgcaggctcaggggggcttgggagga
gctgttctgctccctgtcagcttccaggagggacggcgggcgtcggacacctcactgact
caagggctgaaggcctttcggcagcagctgaggaagaccacgcggaccaaagggtttctg
ggactgaacaaaatcaaggggctggctcgccaggtgtgccaggcccccgccagccgggcc
agcaggggcggcctgagccccttccacgcccctgcacagagcccaggcctgcacggcggc
gcagccggcagccgggagggctggagcctgctggaggaggtgctagagcagcagaggctg
ctccagttacagcaccacccggccgctgcacccggctgctcccaggccccccagccggcc
cctgccccgtttgtgatcgccccctgtgatggccctggggctgccccgctccccagcacc
ctcctcacgtcggggctcccgctgctgccgcccccactcctgcagaccggcgcgtccccg
gtggcctcagcggcgcagctcctggacacacacctgcacattggcaccggccccaccgcc
ctccccgctgtgcccccaccacgcctggccaggctggccccaggttgtgagcccctgggg
ctgctgcagggggactgtgagatggaggacctgatgccctgctccctaggcacgtttgtc
ctggtgcagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (4)   
   KEGG DISEASE (2)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (37)   
   KEGG ORTHOLOGY (1)   
   RefGene (29)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (14)   
   RefSeq(nuc) (4)   
   GenBank (5)   
   EMBL (5)   
Protein domain (8)   
   Pfam (8)   
All databases (75)   

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