KEGG   Homo sapiens (human): 152110
Entry
152110            CDS       T01001                                 
Symbol
NEK10, CILD44
Name
(RefSeq) NIMA related kinase 10
  KO
K20879  serine/threonine-protein kinase Nek10 [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Disease
H00564  Primary ciliary dyskinesia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    152110 (NEK10)
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    152110 (NEK10)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     152110 (NEK10)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  NEK family
   152110 (NEK10)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  Check point factors
   Other check point factors
    152110 (NEK10)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like Pkinase_fungal APH ABC1 RIO1 Haspin_kinase
Other DBs
NCBI-GeneID: 152110
NCBI-ProteinID: NP_689747
OMIM: 618726
HGNC: 18592
Ensembl: ENSG00000163491
UniProt: Q6ZWH5 Q8N774
Position
3:complement(27106484..27369383)
AA seq 1172 aa
MPDQDKKVKTTEKSTDKQQEITIRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNSMTKS
EPAIRAGGHRARGQWHESTEAVELENFSINYKNERNFSKHPQRKLFQEIFTALVKNRLIS
REWVNRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGIENLAQYMEIVANEYLGYGEEQH
TVDKLVNMTYIFQKLAAVKDQREWVTTSGAHKTLVNLLGARDTNVLLGSLLALASLAESQ
ECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCAEPQVKEQVKLYEGIPVLLSLL
HSDHLKLLWSIVWILVQVCEDPETSVEIRIWGGIKQLLHILQGDRNFVSDHSSIGSLSSA
NAAGRIQQLHLSEDLSPREIQENTFSLQAACCAALTELVLNDTNAHQVVQENGVYTIAKL
ILPNKQKNAAKSNLLQCYAFRALRFLFSMERNRPLFKRLFPTDLFEIFIDIGHYVRDISA
YEELVSKLNLLVEDELKQIAENIESINQNKAPLKYIGNYAILDHLGSGAFGCVYKVRKHS
GQNLLAMKEVNLHNPAFGKDKKDRDSSVRNIVSELTIIKEQLYHPNIVRYYKTFLENDRL
YIVMELIEGAPLGEHFSSLKEKHHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNN
IMLGDKDKVTVTDFGLAKQKQENSKLTSVVGTILYSCPEVLKSEPYGEKADVWAVGCILY
QMATLSPPFYSTNMLSLATKIVEAVYEPVPEGIYSEKVTDTISRCLTPDAEARPDIVEVS
SMISDVMMKYLDNLSTSQLSLEKKLERERRRTQRYFMEANRNTVTCHHELAVLSHETFEK
ASLSSSSSGAASLKSELSESADLPPEGFQASYGKDEDRACDEILSDDNFNLENAEKDTYS
EVDDELDISDNSSSSSSSPLKESTFNILKRSFSASGGERQSQTRDFTGGTGSRPRPALLP
LDLLLKVPPHMLRAHIKEIEAELVTGWQSHSLPAVILRNLKDHGPQMGTFLWQASAGIAV
SQRKVRQISDPIQQILIQLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKS
EIKKLSQGSPEPIEPNFFTADYHLLHRSSGGNSLSPNDPTGLPTSIELEEGITYEQMQTV
IEEVLEESGYYNFTSNRYHSYPWGTKNHPTKR
NT seq 3519 nt   +upstreamnt  +downstreamnt
atgcctgatcaagataaaaaggtgaagaccacagaaaaatcaactgataaacagcaagaa
atcaccatcagggactattcagatcttaaaagacttcggtgccttttgaacgtccaatca
agcaaacaacagcttccagccattaacttcgatagtgcccaaaatagcatgacgaagtct
gagcccgccatcagggcgggtggacacagagctcggggtcagtggcatgaatccacagaa
gctgttgaacttgaaaattttagtataaactacaagaatgagagaaatttcagcaaacat
cctcagcgtaaactatttcaggagatctttaccgccttggtgaaaaatagactcataagc
agagagtgggttaatcgagccccatctattcattttctgagagtgttaatctgtctgagg
ctactaatgagggatccatgttatcaggaaatactccatagcttgggtgggattgaaaac
ctagctcagtatatggagattgtagccaatgagtacctcggctatggagaagagcagcac
actgtggacaagctggtcaacatgacatatatttttcaaaaacttgctgcagtcaaagat
caaagagaatgggtcaccacaagtggagcccacaagacattagtaaatttacttggtgcc
cgagatactaatgttctattgggttcccttctggctctggctagtttagcagaaagtcaa
gaatgtagggagaagataagtgaactcaacattgtagaaaatctgttgatgattttacat
gaatatgacttgctttctaaaagactaacagcggagttgctgcgcctactttgtgcagag
ccccaggtgaaagagcaggtgaagctctatgaggggataccggtcctcctcagtctgctc
cactctgaccacttgaagctcctctggagcattgtctggattctggtacaggtttgtgag
gaccctgagaccagcgtggaaattcgcatttggggaggcatcaaacagcttcttcatatt
ttacaaggagacagaaattttgtttctgatcactcctccattggaagcctgtccagtgca
aatgctgcaggccgaatccagcagcttcatttatcagaagacttgagccctagggaaata
caagaaaatactttctcacttcaagcagcctgctgtgctgccctcactgagctggtgctc
aatgacaccaatgcccaccaggtggttcaggaaaatggtgtatatacaatagcaaaatta
attttaccaaataagcaaaagaatgcagcaaaaagtaatctattacagtgttatgctttc
agagccttgagatttctcttcagtatggaaagaaacagaccactctttaaaagacttttc
cccacagacttgtttgagatcttcattgacatagggcattatgtacgtgatatcagtgct
tatgaagaattggtatccaagctgaatttattagtggaggatgaactgaagcaaattgct
gaaaatattgaaagcattaatcagaacaaagctcctttgaaatatataggcaactatgca
attttggatcatcttggaagtggagcttttggctgtgtttacaaggttagaaagcatagt
ggtcaaaatcttttagcaatgaaagaggtcaatttacataacccagcatttggaaaggat
aagaaagatcgagacagcagcgtaaggaatattgtttctgaattaacaataattaaagag
cagctttatcatcccaacattgtacgttattacaaaacatttctggaaaatgataggttg
tacatagttatggagctgatagaaggagccccgcttggagagcatttcagttctttgaag
gaaaaacatcaccattttactgaagaaagactatggaaaatatttatacagctgtgctta
gctcttcgatacttacacaaggagaagaggattgtccatagagatctgacaccaaacaac
attatgttgggggataaggacaaagtaaccgttactgactttggcctggcaaagcaaaaa
caagaaaacagtaaactcacctctgtggttggaacaatcctgtattcttgccccgaggta
ctgaagagtgagccgtatggggagaaggctgatgtctgggcagtaggctgcatcctttat
cagatggcgactttgagtccccccttctacagcactaacatgctgtccttggctacaaaa
atagtggaggcggtatatgaaccagtcccagaaggtatctactctgaaaaagtaacagac
accatcagcaggtgcctcactcctgatgcggaagctcgtccagatattgtagaagtcagt
tcgatgatatcagatgtcatgatgaaatatttagacaacttatctacatcccagttgtcc
ttggaaaagaagctagaacgggaacgaagacgcacacaaaggtattttatggaagccaac
cggaacaccgtcacatgtcaccatgagctggctgttctatctcacgagacctttgagaag
gcaagtttgagtagcagcagcagtggagcagccagcctgaaaagtgaactttcagaaagc
gcagacctgccccctgaaggcttccaggcctcctatggtaaagacgaagacagggcctgt
gacgaaatcctgtcagatgataacttcaacctggaaaatgctgagaaagatacatattca
gaggtagatgatgaattggacatttcggataactccagcagctccagttcaagccctctg
aaagaatctacattcaacattttaaagagaagttttagtgcttcaggaggagaaagacaa
tcccaaacaagggacttcactggaggaacaggatcaagaccaagaccagctttgctgcct
cttgacctgcttctgaaagtgccaccccacatgctcagggcccacattaaggaaatagag
gctgagttagtgacagggtggcagtcccatagccttcctgctgtgattcttcgaaatctc
aaagatcatgggccacagatgggcacattcttgtggcaagcatcagcaggaattgctgtg
tcccagaggaaagtgcgtcagatcagtgatcctattcagcagatattaattcagctgcac
aaaataatctatatcacacagcttcctccagctttgcaccacaatttgaaaagaagggtt
atagagagattcaagaaatccctcttcagccagcagagtaacccttgtaatttgaaatct
gaaattaaaaagttatctcagggatctccagaaccgattgagcccaactttttcacagca
gattaccatttattacatcgttcatccggtggaaacagcctgtccccaaatgaccctaca
ggtttaccaaccagcattgaattggaggaaggaataacatatgaacagatgcagactgtg
attgaagaagtccttgaggaaagtggctattacaattttacatctaacaggtatcattcc
tatccatgggggaccaagaatcacccaaccaaaagatga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (52)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (49)   
DNA sequence (71)   
   RefSeq(nuc) (49)   
   GenBank (11)   
   EMBL (11)   
Protein domain (8)   
   Pfam (8)   
All databases (156)   

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