KEGG T01001: 155

Homo sapiens (human): 155

Entry

155               CDS       T01001

Symbol

ADRB3, BETA3AR

Name

(RefSeq) adrenoceptor beta 3

K04143

adrenergic receptor beta-3

Organism

hsa Homo sapiens (human)

Pathway

hsa04020

Calcium signaling pathway

hsa04022

cGMP-PKG signaling pathway

hsa04080

Neuroactive ligand-receptor interaction

hsa04714

Thermogenesis

hsa04923

Regulation of lipolysis in adipocytes

hsa04924

Renin secretion

hsa04970

Salivary secretion

hsa05207

Chemical carcinogenesis - receptor activation

Network

nt06529 Thermogenesis

Element

N01688

ADRB3-UCP1 signaling pathway

Disease

H02106

Genetic obesity

Drug target

Adaprolol maleate:

D02765

Alprenolol (DG00303):

D01182 D07156

Alprenoxime hydrochloride:

Amibegron (DG01237):

Arbutamine:

Befunolol (DG01138):

Beradilol monoethyl maleate:

D09843

Bopindolol (DG00310):

D01794 D07537

Bufetolol hydrochloride:

D01504<JP>

Bunitrolol hydrochloride:

D01444

Bupranolol (DG00311):

D01454 D07590

Carteolol (DG00308):

D00599<JP/US> D07624

Cimaterol:

D03502

Cloranolol:

D07183

Dexpropranolol hydrochloride:

D03729

Diacetolol hydrochloride:

D03759

Dilevalol hydrochloride:

D01906

Dipivefrine (DG01129):

D01017 D02349

Droxidopa:

D01277<JP/US>

Ephedrine (DG00227):

D00124 D01386<JP/US> D04018<US>

Epinephrine (DG00013):

D00095<JP/US> D00996 D02149

Epinephryl borate:

D04026

Etilefrine (DG00210):

D01573<JP> D07931

Exaprolol hydrochloride:

D04120

Fasobegron:

D09344

Flestolol sulfate:

D04190

Isoprenaline (DG00211):

D01390<JP/US> D02066 D02150<JP> D08090

Levobunolol (DG01136):

D01025<JP/US> D08115

Medroxalol (DG01317):

D04888 D04889

Mepindolol:

D07181

Methylephedrine (DG01229):

D01952 D02109<JP> D08206 D09842

Metipranolol (DG01137):

D02081 D02374

Mirabegron:

D09535<JP/US>

Nipradilol:

D01691<JP>

Norepinephrine (DG00212):

D00076<JP> D05206<US> D08284 D09794

Octodrine:

D05228

Oxprenolol (DG00304):

D01806 D08318

Pamatolol sulfate:

D05345

Penbutolol (DG00312):

D00602 D08074

Phenylpropanolamine (DG01041):

D01224 D05466 D08368

Pindolol:

D00513<JP/US>

Propranolol (DG00305):

D00483<JP/US> D08443

Pseudoephedrine (DG01042):

D00485 D05648 D05649 D08449

Racephedrine hydrochloride:

D08982

Racepinephrine (DG01444):

D05688 D05689

Ritobegron ethyl hydrochloride:

D09732

Solabegron hydrochloride:

D05879

Talibegron hydrochloride:

D02702

Talinolol:

D07184

Tazolol hydrochloride:

D06014

Tertatolol (DG00309):

D07182 D08572

Tilisolol (DG01322):

D01795 D08598

Tiprenolol hydrochloride:

D06162

Tolamolol:

D06176

Vibegron:

D10433<JP/US>

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    155 (ADRB3)
   04022 cGMP-PKG signaling pathway
    155 (ADRB3)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    155 (ADRB3)
09150 Organismal Systems
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    155 (ADRB3)
   04924 Renin secretion
    155 (ADRB3)
  09154 Digestive system
   04970 Salivary secretion
    155 (ADRB3)
  09159 Environmental adaptation
   04714 Thermogenesis
    155 (ADRB3)
09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    155 (ADRB3)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    155 (ADRB3)
G protein-coupled receptors [BR:hsa04030]
Rhodopsin family
  Biogenic amine
   Adrenaline
    155 (ADRB3)

SSDB

Motif

Pfam:

7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx 7TM_GPCR_Srv

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Position

8:complement(37962990..37966599)

AA seq 408 aa
MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS

NT seq 1227 nt +upstreamnt +downstreamnt
atggctccgtggcctcacgagaacagctctcttgccccatggccggacctccccaccctg
gcgcccaataccgccaacaccagtgggctgccaggggttccgtgggaggcggccctagcc
ggggccctgctggcgctggcggtgctggccaccgtgggaggcaacctgctggtcatcgtg
gccatcgcctggactccgagactccagaccatgaccaacgtgttcgtgacttcgctggcc
gcagccgacctggtgatgggactcctggtggtgccgccggcggccaccttggcgctgact
ggccactggccgttgggcgccactggctgcgagctgtggacctcggtggacgtgctgtgt
gtgaccgccagcatcgaaaccctgtgcgccctggccgtggaccgctacctggctgtgacc
aacccgctgcgttacggcgcactggtcaccaagcgctgcgcccggacagctgtggtcctg
gtgtgggtcgtgtcggccgcggtgtcgtttgcgcccatcatgagccagtggtggcgcgta
ggggccgacgccgaggcgcagcgctgccactccaacccgcgctgctgtgccttcgcctcc
aacatgccctacgtgctgctgtcctcctccgtctccttctaccttcctcttctcgtgatg
ctcttcgtctacgcgcgggttttcgtggtggctacgcgccagctgcgcttgctgcgcggg
gagctgggccgctttccgcccgaggagtctccgccggcgccgtcgcgctctctggccccg
gccccggtggggacgtgcgctccgcccgaaggggtgcccgcctgcggccggcggcccgcg
cgcctcctgcctctccgggaacaccgggccctgtgcaccttgggtctcatcatgggcacc
ttcactctctgctggttgcccttctttctggccaacgtgctgcgcgccctggggggcccc
tctctagtcccgggcccggctttccttgccctgaactggctaggttatgccaattctgcc
ttcaacccgctcatctactgccgcagcccggactttcgcagcgccttccgccgtcttctg
tgccgctgcggccgtcgcctgcctccggagccctgcgccgccgcccgcccggccctcttc
ccctcgggcgttcctgcggcccggagcagcccagcgcagcccaggctttgccaacggctc
gacggggcttcttggggagtttcttag

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