KEGG   Homo sapiens (human): 1562
Entry
1562              CDS       T01001                                 
Symbol
CYP2C18, CPCI, CYP2C, CYP2C17, P450-6B/29C, P450IIC17
Name
(RefSeq) cytochrome P450 family 2 subfamily C member 18
  KO
K17720  cytochrome P450 family 2 subfamily C18 [EC:1.14.14.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00830  Retinol metabolism
hsa01100  Metabolic pathways
hsa04726  Serotonergic synapse
hsa05204  Chemical carcinogenesis - DNA adducts
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    1562 (CYP2C18)
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    1562 (CYP2C18)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    1562 (CYP2C18)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:hsa00199]
    1562 (CYP2C18)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     1562 (CYP2C18)
Cytochrome P450 [BR:hsa00199]
 Cytochrome P450, animal type
  CYP2 family
   1562 (CYP2C18)
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 1562
NCBI-ProteinID: NP_000763
OMIM: 601131
HGNC: 2620
Ensembl: ENSG00000108242
UniProt: P33260 Q7Z348
Structure
Position
10:94683729..94736190
AA seq 490 aa
MDPAVALVLCLSCLFLLSLWRQSSGRGRLPSGPTPLPIIGNILQLDVKDMSKSLTNFSKV
YGPVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRW
KEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTNASPCDPTFILGCAPCNVICS
VIFHDRFDYKDQRFLNLMEKFNENLRILSSPWIQVCNNFPALIDYLPGSHNKIAENFAYI
KSYVLERIKEHQESLDMNSARDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTE
TTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYID
LLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFK
KSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQVDPKDIDITPIANAFGRVP
PLYQLCFIPV
NT seq 1473 nt   +upstreamnt  +downstreamnt
atggatccagctgtggctctggtgctctgtctctcctgtttgtttctcctttcactctgg
aggcagagctctggaagagggaggctcccgtctggccccactcctctcccgattattgga
aatatcctgcagttagatgttaaggacatgagcaaatccttaaccaatttctcaaaagtc
tatggccctgtgttcactgtgtattttggcctgaagcccattgtggtgttgcatggatat
gaagcagtgaaggaggccctgattgatcatggagaggagttttctggaagaggaagtttt
ccagtggctgaaaaagttaacaaaggacttggaatccttttcagcaatggaaagagatgg
aaggagatccggcgtttctgcctcatgactctgcggaattttgggatggggaagaggagc
atcgaggaccgtgttcaagaggaagcccgctgccttgtggaggagttgagaaaaaccaat
gcctcaccctgtgatcccactttcatcctgggctgtgctccctgcaatgtgatctgctct
gttattttccatgatcgatttgattataaagatcagaggtttcttaacttgatggaaaaa
ttcaatgaaaacctcaggattctgagctctccatggatccaggtctgcaataatttccct
gctctcatcgattatctcccaggaagtcataataaaatagctgaaaattttgcttacatt
aaaagttatgtattggagagaataaaagaacatcaagaatccctggacatgaacagtgct
cgggactttattgattgtttcctgatcaaaatggaacaggaaaagcacaatcaacagtct
gaatttactgttgaaagcttgatagccactgtaactgatatgtttggggctggaacagag
acaacgagcaccactctgagatatggactcctgctcctgctgaagtacccagaggtcaca
gctaaagtccaggaagagattgaatgtgtagttggcagaaaccggagcccctgtatgcag
gacaggagtcacatgccctacacagatgctgtggtgcacgagatccagagatacattgac
ctcctccccaccaacctgccccatgcagtgacctgtgatgttaaattcaaaaactacctc
atccccaagggcacgaccataataacatccctgacttctgtgctgcacaatgacaaagaa
ttccccaacccagagatgtttgaccctggccactttctggataagagtggcaactttaag
aaaagtgactacttcatgcctttctcagcaggaaaacggatgtgtatgggagagggcctg
gcccgcatggagctgtttttattcctgaccaccattttgcagaactttaacctgaaatct
caggttgacccaaaggatattgacatcacccccattgccaatgcatttggtcgtgtgcca
cccttgtaccagctctgcttcattcctgtctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (1)   
   OMIM (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (26)   
   RefSeq(nuc) (2)   
   GenBank (12)   
   EMBL (12)   
3D Structure (2)   
   PDB (2)   
Protein domain (1)   
   Pfam (1)   
All databases (62)   

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