KEGG   Homo sapiens (human): 1572
Entry
1572              CDS       T01001                                 
Symbol
CYP2F1, C2F1, CYP2F, CYPIIF1
Name
(RefSeq) cytochrome P450 family 2 subfamily F member 1
  KO
K07416  cytochrome P450 family 2 subfamily F [EC:1.14.14.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00980  Metabolism of xenobiotics by cytochrome P450
hsa05208  Chemical carcinogenesis - reactive oxygen species
Network
nt06251  CYP-mediated ROS formation (cancer)
  Element
N01399  Benzene to CYP-mediated metabolism
N01400  Benzene to CYP-mediated metabolism
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    1572 (CYP2F1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    1572 (CYP2F1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:hsa00199]
    1572 (CYP2F1)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     1572 (CYP2F1)
Cytochrome P450 [BR:hsa00199]
 Cytochrome P450, animal type
  CYP2 family
   1572 (CYP2F1)
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 1572
NCBI-ProteinID: NP_000765
OMIM: 124070
HGNC: 2632
Ensembl: ENSG00000197446
UniProt: P24903
Position
19:41114432..41128381
AA seq 491 aa
MDSISTAILLLLLALVCLLLTLSSRDKGKLPPGPRPLSILGNLLLLCSQDMLTSLTKLSK
EYGSMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDR
WKVLRQFSIQILRNFGMGKRSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIIC
SVLFGSRFDYDDERLLTIIRLINDNFQIMSSPWGELYDIFPSLLDWVPGPHQRIFQNFKC
LRDLIAHSVHDHQASLDPRSPRDFIQCFLTKMAEEKEDPLSHFHMDTLLMTTHNLLFGGT
KTVSTTLHHAFLALMKYPKVQARVQEEIDLVVGRARLPALKDRAAMPYTDAVIHEVQRFA
DIIPMNLPHRVTRDTAFRGFLIPKGTDVITLLNTVHYDPSQFLTPQEFNPEHFLDANQSF
KKSPAFMPFSAGRRLCLGESLARMELFLYLTAILQSFSLQPLGAPEDIDLTPLSSGLGNL
PRPFQLCLRPR
NT seq 1476 nt   +upstreamnt  +downstreamnt
atggacagcataagcacagccatcttactcctgctcctggctctcgtctgtctgctcctg
accctaagctcaagagataagggaaagctgcctccgggacccagacccctctcaatcctg
ggaaacctgctgctgctttgctcccaagacatgctgacttctctcactaagctgagcaag
gagtatggctccatgtacacagtgcacctgggacccaggcgggtggtggtcctcagcggg
taccaagctgtgaaggaggccctggtggaccagggagaggagtttagtggccgcggtgac
taccctgcctttttcaactttaccaagggcaatggcatcgccttctccagtggggatcga
tggaaggtcctgagacagttctctatccagattctacggaatttcgggatggggaagaga
agcattgaggagcgaatcctagaggagggcagcttcctgctggcggagctgcggaaaact
gaaggcgagccctttgaccccacgtttgtgctgagtcgctcagtgtccaacattatctgt
tccgtgctcttcggcagccgcttcgactatgatgatgagcgtctgctcaccattatccgc
cttatcaatgacaacttccaaatcatgagcagcccctggggcgagttgtacgacatcttc
ccgagcctcctggactgggtgcctgggccgcaccaacgcatcttccagaacttcaagtgc
ctgagagacctcatcgcccacagcgtccacgaccaccaggcctcgctagaccccagatct
ccccgggacttcatccagtgcttcctcaccaagatggcagaggagaaggaggacccactg
agccacttccacatggataccctgctgatgaccacacataacctgctctttggcggcacc
aagacggtgagcaccacgctgcaccacgccttcctggcactcatgaagtacccaaaagtt
caagcccgcgtgcaggaggagatcgacctcgtggtgggacgcgcgcggctgccggcgctg
aaggaccgcgcggccatgccttacacagacgcggtgatccacgaggtgcagcgctttgca
gacatcatccccatgaacttgccgcaccgcgtcactagggacacggcctttcgcggcttc
ctgatacccaagggcaccgatgtcatcaccctccttaacaccgtccactacgaccccagc
cagttcctgacgccccaggagttcaaccccgagcattttttggatgccaatcagtccttc
aagaagagtccagccttcatgcccttctcagctgggcgccgtctgtgcctgggagagtcg
ctggcgcgcatggagctctttctgtacctcaccgccatcctgcagagcttttcgctgcag
ccgctgggtgcgcccgaggacatcgacctgaccccactcagctcaggtcttggcaatttg
ccgcggcctttccagctgtgcctgcgcccgcgctaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (3)   
   KEGG NETWORK (3)   
Disease (1)   
   OMIM (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (24)   
   RefSeq(nuc) (8)   
   GenBank (8)   
   EMBL (8)   
Protein domain (1)   
   Pfam (1)   
All databases (65)   

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