KEGG T01001: 1591

Homo sapiens (human): 1591

Entry

1591              CDS       T01001

Symbol

CYP24A1, CP24, CYP24, HCAI, HCINF1, P450-CC24

Name

(RefSeq) cytochrome P450 family 24 subfamily A member 1

K07436

vitamin D3 24-hydroxylase [EC:1.14.15.16]

Organism

hsa Homo sapiens (human)

Pathway

hsa00100

Steroid biosynthesis

hsa01100

Metabolic pathways

hsa04928

Parathyroid hormone synthesis, secretion and action

hsa05206

MicroRNAs in cancer

Disease

H01371

Hypercalcemia infantile

Brite

KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    1591 (CYP24A1)
09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    1591 (CYP24A1)
09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    1591 (CYP24A1)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:hsa00199]
    1591 (CYP24A1)
Enzymes [BR:hsa01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.16  vitamin D3 24-hydroxylase
     1591 (CYP24A1)
Cytochrome P450 [BR:hsa00199]
Cytochrome P450, animal type
  CYP24 family
   1591 (CYP24A1)

SSDB

Motif

Pfam:

p450

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Position

20:complement(54143538..54173986)

AA seq 514 aa
MSSPISKSRSLAAFLQQLRSPRQPPRLVTSTAYTSPQPREVPVCPLTAGGETQNAAALPG
PTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLGSFESVHLGSPCLLEALYR
TESAYPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMKPGEVMKLDNKIN
EVLADFMGRIDELCDERGHVEDLYSELNKWSFESICLVLYEKRFGLLQKNAGDEAVNFIM
AIKTMMSTFGRMMVTPVELHKSLNTKVWQDHTLAWDTIFKSVKACIDNRLEKYSQQPSAD
FLCDIYHQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVL
PENQVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQ
VLGSSEDNFEDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIV
RKYDIQATDNEPVEMLHSGTLVPSRELPIAFCQR

NT seq 1545 nt +upstreamnt +downstreamnt
atgagctcccccatcagcaagagccgctcgcttgccgccttcctgcagcagctgcgcagt
ccgaggcagcccccgagactggtgacatctacggcgtacacgtcccctcagccgcgagag
gtgccagtctgcccgctgacagctggtggcgagactcagaacgcggccgccctgccgggc
cccaccagctggccactgctgggcagcctgctgcagattctctggaaagggggtctcaag
aaacagcacgacaccctggtggagtaccacaagaagtatggcaagattttccgcatgaag
ttgggttcctttgagtcggtgcacctgggctcgccatgcctgctggaagcgctgtaccgc
accgagagcgcgtacccgcagcggctggagatcaaaccgtggaaggcctatcgcgactac
cgcaaagaaggctacgggctgctgatcctggaaggggaagactggcagcgggtccggagt
gcctttcaaaagaaactaatgaaaccaggggaagtgatgaagctggacaacaaaatcaat
gaggtcttggccgattttatgggcagaatagatgagctctgtgatgaaagaggccacgtt
gaagacttgtacagcgaactgaacaaatggtcgtttgaaagtatctgcctcgtgttgtat
gagaagagatttgggcttctccagaagaatgcaggggatgaagctgtgaacttcatcatg
gccatcaaaacaatgatgagcacgtttgggaggatgatggtcactccagtcgagctgcac
aagagcctcaacaccaaggtctggcaggaccacactctggcctgggacaccattttcaaa
tcagtcaaagcttgtatcgacaaccggttagagaagtattctcagcagcctagtgcagat
ttcctttgtgacatttatcaccagaatcggctttcaaagaaagaattgtatgctgctgtc
acagagctccagctggctgcggtggaaacgacagcaaacagtctaatgtggattctctac
aatttatcccgtaatccccaagtgcaacaaaagcttcttaaggaaattcaaagtgtatta
cctgagaatcaggtgccacgggcagaagatttgaggaatatgccgtatttaaaagcctgt
ctgaaagaatctatgaggcttacgccgagtgtaccatttacaactcggactcttgacaag
gcaacagttctgggtgaatatgctttacccaaaggaacagtgctcatgctaaatacccag
gtgttgggatccagtgaagacaattttgaagattcaagtcagtttagacctgaacgttgg
cttcaggagaaggaaaaaattaatccttttgcgcatcttccatttggcgttggaaaaaga
atgtgcattggtcgccgattagcagagcttcaactgcatttggctctttgttggattgtc
cgcaaatacgacatccaggccacagacaatgagcctgttgagatgctacactcaggcacc
ctggtgcccagccgggaactccccatcgcgttttgccagcgataa

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