KEGG   Homo sapiens (human): 1718
Entry
1718              CDS       T01001                                 
Symbol
DHCR24, DCE, Nbla03646, SELADIN1, seladin-1
Name
(RefSeq) 24-dehydrocholesterol reductase
  KO
K09828  Delta24-sterol reductase [EC:1.3.1.72 1.3.1.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00100  Steroid biosynthesis
hsa01100  Metabolic pathways
Module
hsa_M00101  Cholesterol biosynthesis, FPP => cholesterol
Network
nt06034  Cholesterol biosynthesis
  Element
N01624  Cholesterol biosynthesis
Disease
H00617  Desmosterolosis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    1718 (DHCR24)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.72  Delta24-sterol reductase
     1718 (DHCR24)
SSDB
Motif
Pfam: FAD_binding_4 Pam17
Other DBs
NCBI-GeneID: 1718
NCBI-ProteinID: NP_055577
OMIM: 606418
HGNC: 2859
Ensembl: ENSG00000116133
UniProt: Q15392
Position
1:complement(54849627..54887195)
AA seq 516 aa
MEPAVSLAVCALLFLLWVRLKGLEFVLIHQRWVFVCLFLLPLSLIFDIYYYVRAWVVFKL
SSAPRLHEQRVRDIQKQVREWKEQGSKTFMCTGRPGWLTVSLRVGKYKKTHKNIMINLMD
ILEVDTKKQIVRVEPLVTMGQVTALLTSIGWTLPVLPELDDLTVGGLIMGTGIESSSHKY
GLFQHICTAYELVLADGSFVRCTPSENSDLFYAVPWSCGTLGFLVAAEIRIIPAKKYVKL
RFEPVRGLEAICAKFTHESQRQENHFVEGLLYSLDEAVIMTGVMTDEAEPSKLNSIGNYY
KPWFFKHVENYLKTNREGLEYIPLRHYYHRHTRSIFWELQDIIPFGNNPIFRYLFGWMVP
PKISLLKLTQGETLRKLYEQHHVVQDMLVPMKCLQQALHTFQNDIHVYPIWLCPFILPSQ
PGLVHPKGNEAELYIDIGAYGEPRVKHFEARSCMRQLEKFVRSVHGFQMLYADCYMNREE
FWEMFDGSLYHKLREKLGCQDAFPEVYDKICKAARH
NT seq 1551 nt   +upstreamnt  +downstreamnt
atggagcccgccgtgtcgctggccgtgtgcgcgctgctcttcctgctgtgggtgcgcctg
aaggggctggagttcgtgctcatccaccagcgctgggtgttcgtgtgcctcttcctcctg
ccgctctcgcttatcttcgatatctactactacgtgcgcgcctgggtggtgttcaagctc
agcagcgctccgcgcctgcacgagcagcgcgtgcgggacatccagaagcaggtgcgggaa
tggaaggagcagggtagcaagaccttcatgtgcacggggcgccctggctggctcactgtc
tcactacgtgtcgggaagtacaagaagacacacaaaaacatcatgatcaacctgatggac
attctggaagtggacaccaagaaacagattgtccgtgtggagcccttggtgaccatgggc
caggtgactgccctgctgacctccattggctggactctccccgtgttgcctgagcttgat
gacctcacagtggggggcttgatcatgggcacaggcatcgagtcatcatcccacaagtac
ggcctgttccaacacatctgcactgcttacgagctggtcctggctgatggcagctttgtg
cgatgcactccgtccgaaaactcagacctgttctatgccgtaccctggtcctgtgggacg
ctgggtttcctggtggccgctgagatccgcatcatccctgccaagaagtacgtcaagctg
cgtttcgagccagtgcggggcctggaggctatctgtgccaagttcacccacgagtcccag
cggcaggagaaccacttcgtggaagggctgctctactccctggatgaggctgtcattatg
acaggggtcatgacagatgaggcagagcccagcaagctgaatagcattggcaattactac
aagccgtggttctttaagcatgtggagaactatctgaagacaaaccgagagggcctggag
tacattcccttgagacactactaccaccgccacacgcgcagcatcttctgggagctccag
gacattatcccctttggcaacaaccccatcttccgctacctctttggctggatggtgcct
cccaagatctccctcctgaagctgacccagggtgagaccctgcgcaagctgtacgagcag
caccacgtggtgcaggacatgctggtgcccatgaagtgcctgcagcaggccctgcacacc
ttccaaaacgacatccacgtctaccccatctggctgtgtccgttcatcctgcccagccag
ccaggcctagtgcaccccaaaggaaatgaggcagagctctacatcgacattggagcatat
ggggagccgcgtgtgaaacactttgaagccaggtcctgcatgaggcagctggagaagttt
gtccgcagcgtgcatggcttccagatgctgtatgccgactgctacatgaaccgggaggag
ttctgggagatgtttgatggctccttgtaccacaagctgcgagagaagctgggttgccag
gacgccttccccgaggtgtacgacaagatctgcaaggccgccaggcactga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (2)   
   KEGG MODULE (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (20)   
   KEGG COMPOUND (20)   
Chemical reaction (10)   
   KEGG ENZYME (1)   
   KEGG REACTION (9)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (12)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (33)   
   RefSeq(nuc) (1)   
   GenBank (16)   
   EMBL (16)   
Protein domain (2)   
   Pfam (2)   
All databases (104)   

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