KEGG   Homo sapiens (human): 1730
Entry
1730              CDS       T01001                                 
Symbol
DIAPH2, DIA, DIA2, DRF2, POF, POF2, POF2A
Name
(RefSeq) diaphanous related formin 2
  KO
K05741  diaphanous 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04810  Regulation of actin cytoskeleton
hsa04820  Cytoskeleton in muscle cells
Disease
H00627  Premature ovarian failure
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    1730 (DIAPH2)
   04810 Regulation of actin cytoskeleton
    1730 (DIAPH2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    1730 (DIAPH2)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Formins
     1730 (DIAPH2)
SSDB
Motif
Pfam: FH2 Drf_FH3 Drf_GBD Drf_DAD DUF6779 EMP24_GP25L Drf_FH1
Other DBs
NCBI-GeneID: 1730
NCBI-ProteinID: NP_006720
OMIM: 300108
HGNC: 2877
Ensembl: ENSG00000147202
UniProt: O60879
Position
X:96684842..97604997
AA seq 1101 aa
MEQPGAAASGAGGGSEEPGGGRSNKRSAGNRAANEEETKNKPKLNIQIKTLADDVRDRIT
SFRKSTVKKEKPLIQHPIDSQVAMSEFPAAQPLYDERSLNLSEKEVLDLFEKMMEDMNLN
EEKKAPLRNKDFTTKREMVVQYISATAKSGGLKNSKHECTLSSQEYVHELRSGISDEKLL
NCLESLRVSLTSNPVSWVNNFGHEGLGLLLDELEKLLDKKQQENIDKKNQYKLIQCLKAF
MNNKFGLQRILGDERSLLLLARAIDPKQPNMMTEIVKILSAICIVGEENILDKLLGAITT
AAERNNRERFSPIVEGLENQEALQLQVACMQFINALVTSPYELDFRIHLRNEFLRSGLKT
MLPDLKEKENDELDIQLKVFDENKEDDLTELSHRLNDIRAEMDDMNEVYHLLYNMLKDTA
AENYFLSILQHFLLIRNDYYIRPQYYKIIEECVSQIVLHCSGMDPDFKYRQRLDIDLTHL
IDSCVNKAKVEESEQKAAEFSKKFDEEFTARQEAQAELQKRDEKIKELEAEIQQLRTQAQ
VLSSSSGIPGPPAAPPLPGVGPPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPPPPPPLLF
GGPPPPPPLGGVPPPPGISLNLPYGMKQKKMYKPEVSMKRINWSKIEPTELSENCFWLRV
KEDKFENPDLFAKLALNFATQIKVQKNAEALEEKKTGPTKKKVKELRILDPKTAQNLSIF
LGSYRMPYEDIRNVILEVNEDMLSEALIQNLVKHLPEQKILNELAELKNEYDDLCEPEQF
GVVMSSVKMLQPRLSSILFKLTFEEHINNIKPSIIAVTLACEELKKSESFNRLLELVLLV
GNYMNSGSRNAQSLGFKINFLCKIRDTKSADQKTTLLHFIADICEEKYRDILKFPEELEH
VESASKVSAQILKSNLASMEQQIVHLERDIKKFPQAENQHDKFVEKMTSFTKTAREQYEK
LSTMHNNMMKLYENLGEYFIFDSKTVSIEEFFGDLNNFRTLFLEAVRENNKRREMEEKTR
RAKLAKEKAEQEKLERQKKKKQLIDINKEGDETGVMDNLLEALQSGAAFRDRRKRIPRNP
DNRRVPLERSRSRHNGAISSK
NT seq 3306 nt   +upstreamnt  +downstreamnt
atggagcagcccggggcggcggcgtcgggagcgggaggcggcagcgaggaacccggtggg
ggccggagcaacaagcggagcgcggggaaccgggccgccaatgaagaggaaacgaaaaac
aaacccaaattgaacattcaaataaaaactttggcagatgatgtgcgtgaccgaattaca
agttttagaaaatctactgtcaaaaaagaaaaacctcttattcaacatcctattgattct
caagtcgcgatgagtgagtttcctgcagctcagccattatatgatgaacgatctttgaat
ttgtcagaaaaggaagtattggatctctttgaaaaaatgatggaggacatgaaccttaac
gaagagaaaaaagctcctttacgaaacaaagactttaccaccaaacgtgagatggttgtc
cagtatatttctgccactgccaaatctggtgggctgaaaaacagcaaacatgaatgcacc
ctgtcttcacaagaatatgttcatgaattacgatcgggtatatcagatgagaaacttctt
aattgcctagaatccctcagggtttctttaaccagcaatccggtcagctgggttaacaac
tttggccatgaaggtcttggactcttattggatgagctggaaaagcttctggacaaaaaa
cagcaagaaaatattgacaagaagaatcagtataaacttattcaatgcctcaaagcattt
atgaataataagtttggattacaaaggattctaggagatgaaagaagtcttttactattg
gcaagagcaattgaccccaaacaacccaacatgatgactgaaatagtaaaaatactttct
gctatttgcattgttggagaagagaacattctagataaacttttaggggctataacaaca
gcagcagaaagaaataacagggaacgattttcaccaattgtggaaggtttagaaaatcag
gaagccttgcaattacaggtggcctgcatgcagtttataaatgcccttgtcacttctcct
tatgagcttgattttcgaatacatttaaggaatgaattcctccgttcaggactaaaaaca
atgttaccagatctaaaagaaaaagagaatgatgagcttgatattcagttgaaagtattt
gatgaaaacaaagaagatgacctaactgaattatcacaccgtctcaatgacattcgagca
gaaatggatgatatgaatgaagtctaccatcttctatataatatgctgaaggacactgct
gctgaaaattacttcttatctattctacaacattttttgcttatcagaaatgattattat
atcaggccacaatattataaaataattgaggaatgtgtttcacagatagtgctacactgc
agtggtatggatccagacttcaaatacaggcaaagattagacatcgatttaactcatctg
atagattcttgtgtgaacaaggcgaaagttgaagaaagtgaacaaaaagctgcagagttt
tcaaagaagttcgatgaagaattcacagctcgacaggaagctcaagcagagcttcaaaaa
agagatgagaaaatcaaagaacttgaagcagaaatccagcaacttcgaacccaggcacaa
gtactctcaagttcatcaggaattccaggtcctcctgcagcacctccattgccaggtgta
gggccgcctccaccaccacccgcgccacctctacccggaggagctcctcttcctcctcca
ccacctcctttacctggaatgatggggataccaccaccacccccaccaccacttttattt
gggggacctcctccaccaccaccccttggaggagttcctcctcccccaggaatatcactt
aatctaccttatggaatgaagcagaaaaaaatgtataaacctgaagtgtccatgaagaga
atcaattggtcaaagattgaacccacagaattatctgagaactgtttctggttaagagtc
aaagaagacaagtttgagaatccagatctctttgccaaattggcattgaattttgctact
cagataaaagttcaaaagaacgcagaagcattagaagaaaagaagactgggcctacaaag
aagaaagtgaaagaactgagaattttggatcccaaaacagctcagaatctgtccatcttt
ctgggatcatatcgcatgccatatgaagacataagaaacgttattctggaggttaatgaa
gacatgctgagtgaggctttaattcagaaccttgtgaaacatcttcctgagcagaagata
ctcaacgaattagcagagcttaagaatgaatatgatgacctctgtgagcctgaacaattt
ggagttgtgatgagctctgtgaaaatgttacagcctcgtctcagtagtatcctgttcaag
ctcacatttgaagaacacataaacaacatcaaaccaagcatcatagcagtaactcttgcc
tgtgaagaactgaagaaaagtgaaagctttaacagacttttagagttagttcttcttgtt
ggaaactacatgaactcaggctcaagaaatgcccagtctttgggatttaagatcaacttc
ctttgtaagatcagagatactaaatcagcggatcaaaaaacaacccttttgcattttatt
gccgacatttgtgaggaaaaatatcgagatatcctaaaatttcctgaagaactggaacac
gtagaaagtgcaagcaaagtttcagctcaaattctcaagagcaaccttgcatcaatggaa
caacaaattgttcatctggaacgtgacatcaagaaattcccccaagcagaaaatcaacac
gataagtttgtggaaaagatgaccagctttacaaagactgcccgagaacagtatgaaaaa
ctctccaccatgcacaacaacatgatgaagctctatgagaatcttggagaatacttcatt
tttgactcaaagacagtgagcatagaagagttctttggtgatctcaacaacttccgaact
ttgtttttggaagcagtgagagaaaacaataagagaagagaaatggaagagaagaccagg
agggcaaaacttgcaaaagagaaagctgaacaagaaaagttagaacgccagaagaaaaag
aaacaactcattgatataaacaaagagggtgatgagactggtgtgatggataatcttcta
gaagccctacaatcaggtgcagcattcagagaccgtcgaaagcggattccaaggaatcca
gataacagacgagtacctttggaaaggtcacgctctcgccacaatggagctatctcatct
aagtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (24)   
   RefSeq(nuc) (2)   
   GenBank (11)   
   EMBL (11)   
Protein domain (7)   
   Pfam (7)   
All databases (65)   

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