KEGG   Homo sapiens (human): 1735
Entry
1735              CDS       T01001                                 
Symbol
DIO3, 5DIII, D3, DIOIII, TXDI3
Name
(RefSeq) iodothyronine deiodinase 3
  KO
K07754  thyroxine 5-deiodinase [EC:1.21.99.3]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04919  Thyroid hormone signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    1735 (DIO3)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.21  Catalysing the reaction X-H + Y-H = X-Y
   1.21.99  With unknown physiological acceptors
    1.21.99.3  thyroxine 5-deiodinase
     1735 (DIO3)
SSDB
Motif
Pfam: T4_deiodinase AhpC-TSA Redoxin
Other DBs
NCBI-GeneID: 1735
NCBI-ProteinID: NP_001353
OMIM: 601038
HGNC: 2885
Ensembl: ENSG00000197406
UniProt: P55073 Q86TU3
Position
14:101561495..101563452
AA seq 304 aa
MPRQATSRLVVGEGEGSQGASGPAATMLRSLLLHSLRLCAQTASCLVLFPRFLGTAFMLW
LLDFLCIRKHFLGRRRRGQPEPEVELNSEGEEVPPDDPPICVSDDNRLCTLASLKAVWHG
QKLDFFKQAHEGGPAPNSEVVLPDGFQSQHILDYAQGNRPLVLNFGSCTUPPFMARMSAF
QRLVTKYQRDVDFLIIYIEEAHPSDGWVTTDSPYIIPQHRSLEDRVSAARVLQQGAPGCA
LVLDTMANSSSSAYGAYFERLYVIQSGTIMYQGGRGPDGYQVSELRTWLERYDEQLHGAR
PRRV
NT seq 915 nt   +upstreamnt  +downstreamnt
atgcctcgccaggccacgtcgcggttggtggtcggagagggcgaggggtcccagggggct
tcggggcctgcagccaccatgctccgctccctgctgcttcactccttgaggctctgcgcc
cagaccgcctcgtgcctcgtgctcttcccgcgcttcctcggcacggccttcatgctctgg
cttctcgatttcttgtgtatccgcaagcatttcctgggccgccgccgccgggggcagccc
gagcccgaagtggagctcaacagtgaaggcgaggaggtgcctcccgatgacccgcccatc
tgcgtgtccgacgacaaccgcctgtgcaccctggcgtcgctcaaggcggtgtggcatggc
cagaagttggatttcttcaagcaggcgcacgagggcggtccggcgcccaactccgaggtg
gttctgcccgacggcttccagagccagcacatcctcgactacgcgcaagggaaccgcccg
ctggttctcaatttcggcagctgcacctgaccaccgttcatggcgcgcatgagcgccttc
cagcgcctggtcactaagtaccagcgcgacgtcgacttcctcatcatctacatcgaggaa
gcgcacccctccgacggctgggtcaccacggactctccctacatcatcccacagcaccgg
agcctggaggaccgggtcagcgcagcgagggtactgcagcaaggtgcacccggctgcgct
ctggtcctcgacaccatggccaactccagcagctcggcctatggcgcctacttcgagcgt
ctctatgtcatccagagtggcactattatgtaccagggcggccgtggccccgacggctac
caggtctctgagctgcgcacttggttggaacgctatgatgagcaactgcacggcgctcgg
ccccggagggtgtaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (9)   
   RefSeq(nuc) (1)   
   GenBank (4)   
   EMBL (4)   
Protein domain (3)   
   Pfam (3)   
All databases (30)   

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