KEGG   Homo sapiens (human): 1757
Entry
1757              CDS       T01001                                 
Symbol
SARDH, BPR-2, DMGDHL1, SAR, SARD, SDH
Name
(RefSeq) sarcosine dehydrogenase
  KO
K00314  sarcosine dehydrogenase [EC:1.5.8.3]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00260  Glycine, serine and threonine metabolism
hsa01100  Metabolic pathways
Module
hsa_M00974  Betaine metabolism, animals, betaine => glycine
Network
nt06033  Glycine, serine and arginine metabolism
  Element
N01789  Betaine metabolism
Disease
H02657  Sarcosinemia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    1757 (SARDH)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.8  With a flavin or flavoprotein as acceptor
    1.5.8.3  sarcosine dehydrogenase
     1757 (SARDH)
SSDB
Motif
Pfam: DAO GCV_T FAO_M GCV_T_C Pyr_redox_2
Other DBs
NCBI-GeneID: 1757
NCBI-ProteinID: NP_001128179
OMIM: 604455
HGNC: 10536
Ensembl: ENSG00000123453
UniProt: Q9UL12 A8K596
Position
9:complement(133659418..133739955)
AA seq 918 aa
MASLSRALRVAAAHPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPS
RPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSD
VEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESH
VLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGI
RVWTDDFGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPLVAMHHAYVVTER
IEGIQNMPNVRDHDASVYLRLQGDALSVGGYEANPIFWEEVSDKFAFGLFDLDWEVFTQH
IEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGC
GQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHDEPLAG
RNMRRDPLHEELLGQGCVFQERHGWERPGWFHPRGPAPVLEYDYYGAYGSRAHEDYAYRR
LLADEYTFAFPPHHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFSADVSR
PPGSTVYTCMLNHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHI
TTVLQDQKSQCQLIDSSEDLGMISIQGPASRAILQEVLDADLSNEAFPFSTHKLLRAAGH
LVRAMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLINAGYRAIDSLSIEKGYRHW
HADLRPDDSPLEAGLAFTCKLKSPVPFLGREALEQQRAAGLRRRLVCFTMEDKVPMFGLE
AIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMGVTYGAQ
AHLKSPFDPNNKRVKGIY
NT seq 2757 nt   +upstreamnt  +downstreamnt
atggcctcactgagccgagccctacgtgtggctgctgcccaccctcgccagagccctacc
cggggcatggggccatgcaacctgtccagcgcagctggccccacagccgagaagagtgtg
ccatatcagcggaccctgaaggagggacagggcacctcggtggtggcccaaggcccaagc
cggcccctgcccagcacggccaacgtggtggtcattggtggaggcagcttgggctgccag
accctgtaccacctggccaagctgggcatgagtggggcggtgctgctggagcgggagcgg
ctgacctccgggaccacctggcacacggcaggcctgctgtggcagctgcggcccagtgac
gtggaggtggagcttctggcccacactcggcgggtggtgagccgggagctggaggaggag
acgggactacacacgggctggatccagaatgggggcctcttcatcgcgtccaaccggcag
cgcctggacgagtacaagaggctcatgtcgctgggcaaggcgtatggtgtggaatcccat
gtgctgagcccggcagagaccaagactctgtacccgctgatgaatgtggacgacctctac
gggaccctgtatgtgccgcacgacggtaccatggaccccgctggcacctgtaccaccctc
gccagggcagcttctgcccgaggagcacaggtcattgagaactgcccagtgaccggcatt
cgtgtgtggacggatgattttggggtgcggcgggtcgcgggtgtggagactcagcatggt
tccatccagacaccctgcgtggtcaactgtgcaggagtgtgggcaagtgctgtgggccgg
atggctggagtcaaggtcccgctggtggccatgcaccatgcctatgtcgtcaccgagcgc
atcgaggggattcagaacatgcccaatgtccgtgatcatgatgcctctgtctacctccgc
ctccaaggggatgccttgtctgtgggtggctatgaggccaaccccatcttttgggaggag
gtgtcagacaagtttgccttcggcctctttgacctggactgggaggtgttcacccagcac
attgaaggcgccatcaacagggtccccgtgctggagaagacaggaatcaagtccacggtc
tgcggccctgaatccttcacgcccgaccacaagcccctgatgggggaggcacctgagctc
cgagggttcttcctgggctgtggcttcaacagcgcaggaatgatgctgggtggtggctgt
gggcaggagctggcccactggatcatccatgggcgcccggagaaggacatgcatggctat
gacatcaggcgcttccatcactcgctcacggaccacccccgctggatccgagagcgaagc
catgagtcctacgccaagaactactccgtcgtcttcccccacgatgagccgctggccggg
cgcaacatgaggagagacccgctgcacgaggaactccttggacaaggctgcgtgttccag
gagcggcatggctgggagcgaccgggatggtttcatccccgaggcccagctccggtcctc
gagtacgactactacggggcttacgggagccgcgcgcacgaggactacgcctaccgcagg
ctgctggcagacgagtacaccttcgccttcccgccccaccacgacacgatcaagaaggag
tgcctggcctgcagaggggccgccgctgtgtttgacatgtcctacttcgggaagttctac
ctggtggggctggatgcaaggaaggctgccgactggctcttctccgcagatgtcagccga
cccccaggctccaccgtgtacacgtgcatgctcaaccaccgtgggggcaccgagagtgac
ctgactgtcagccgcctggcacccagccaccaggcctccccgctggcccccgcctttgaa
ggggacggttactacctggccatgggcggggccgtggcccagcacaactggtcccacatc
accaccgtgctgcaggaccagaagtcccagtgccagctcatcgacagctccgaggacctg
ggtatgatcagtatccagggcccagccagccgagccattttgcaggaggtgctggacgca
gacctgagcaacgaggccttcccgttctccacccacaagctactgagagccgcagggcac
ctggtccgagccatgcggctgtcctttgtgggggagctgggctgggagctgcacattcca
aaggcgtcctgcgtgcctgtgtaccgggctgtgatggccgcgggtgccaagcacggcctc
atcaacgcagggtaccgcgccatcgactccctgagcattgagaaaggctaccggcactgg
cacgcggacctgcggccagacgacagccccctggaggcaggcctggccttcacctgcaag
ctcaagtcgccggtgcccttcctggggagggaggccctggagcagcagcgggccgcaggc
ctccgccggcgcctggtgtgcttcaccatggaggacaaagtacccatgtttggcctggag
gccatctggaggaacggccaagtggtgggccatgtccggagggctgactttgggttcgcc
atcgacaagaccatcgcctacggttacatccatgaccccagcggtgggccggtctcgctg
gactttgtgaagagcggggactatgccctggagagaatgggggtgacctatggtgcccag
gctcacctgaagtcgcccttcgaccccaacaacaagagggtgaagggaatctactga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (17)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (14)   
DNA sequence (60)   
   RefSeq(nuc) (22)   
   GenBank (19)   
   EMBL (19)   
Protein domain (5)   
   Pfam (5)   
All databases (118)   

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