KEGG   Homo sapiens (human): 189
Entry
189               CDS       T01001                                 
Symbol
AGXT, AGT, AGT1, AGXT1, PH1, SPAT, SPT, Ser-PyrAT, TLH6
Name
(RefSeq) alanine--glyoxylate aminotransferase
  KO
K00830  alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00250  Alanine, aspartate and glutamate metabolism
hsa00260  Glycine, serine and threonine metabolism
hsa00630  Glyoxylate and dicarboxylate metabolism
hsa01100  Metabolic pathways
hsa01200  Carbon metabolism
hsa01210  2-Oxocarboxylic acid metabolism
hsa04146  Peroxisome
Disease
H00117  Primary hyperoxaluria
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    189 (AGXT)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    189 (AGXT)
   00260 Glycine, serine and threonine metabolism
    189 (AGXT)
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    189 (AGXT)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:hsa01007]
    189 (AGXT)
Enzymes [BR:hsa01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.44  alanine---glyoxylate transaminase
     189 (AGXT)
    2.6.1.45  serine---glyoxylate transaminase
     189 (AGXT)
    2.6.1.51  serine---pyruvate transaminase
     189 (AGXT)
Amino acid related enzymes [BR:hsa01007]
 Aminotransferase (transaminase)
  Class V
   189 (AGXT)
SSDB
Motif
Pfam: Aminotran_5 Aminotran_1_2
Other DBs
NCBI-GeneID: 189
NCBI-ProteinID: NP_000021
OMIM: 604285
HGNC: 341
Ensembl: ENSG00000172482
UniProt: P21549
Structure
Position
2:240868824..240880500
AA seq 392 aa
MASHKLLVTPPKALLKPLSIPNQLLLGPGPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEI
KEGIQYVFQTRNPLTLVISGSGHCALEAALVNVLEPGDSFLVGANGIWGQRAVDIGERIG
ARVHPMTKDPGGHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQPLDGFGELCHRYKCLL
LVDSVASLGGTPLYMDRQGIDILYSGSQKALNAPPGTSLISFSDKAKKKMYSRKTKPFSF
YLDIKWLANFWGCDDQPRMYHHTIPVISLYSLRESLALIAEQGLENSWRQHREAAAYLHG
RLQALGLQLFVKDPALRLPTVTTVAVPAGYDWRDIVSYVIDHFDIEIMGGLGPSTGKVLR
IGLLGCNATRENVDRVTEALRAALQHCPKKKL
NT seq 1179 nt   +upstreamnt  +downstreamnt
atggcctctcacaagctgctggtgaccccccccaaggccctgctcaagcccctctccatc
cccaaccagctcctgctggggcctggtccttccaacctgcctcctcgcatcatggcagcc
ggggggctgcagatgatcgggtccatgagcaaggatatgtaccagatcatggacgagatc
aaggaaggcatccagtacgtgttccagaccaggaacccactcacactggtcatctctggc
tcgggacactgtgccctggaggccgccctggtcaatgtgctggagcctggggactccttc
ctggttggggccaatggcatttgggggcagcgagccgtggacatcggggagcgcatagga
gcccgagtgcacccgatgaccaaggaccctggaggccactacacactgcaggaggtggag
gagggcctggcccagcacaagccagtgctgctgttcttaacccacggggagtcgtccacc
ggcgtgctgcagccccttgatggcttcggggaactctgccacaggtacaagtgcctgctc
ctggtggattcggtggcatccctgggcgggacccccctttacatggaccggcaaggcatc
gacatcctgtactcgggctcccagaaggccctgaacgcccctccagggacctcgctcatc
tccttcagtgacaaggccaaaaagaagatgtactcccgcaagacgaagcccttctccttc
tacctggacatcaagtggctggccaacttctggggctgtgacgaccagcccaggatgtac
catcacacaatccccgtcatcagcctgtacagcctgagagagagcctggccctcattgcg
gaacagggcctggagaacagctggcgccagcaccgcgaggccgcggcgtatctgcatggg
cgcctgcaggcactggggctgcagctcttcgtgaaggacccggcgctccggcttcccaca
gtcaccactgtggctgtacccgctggctatgactggagagacatcgtcagctacgtcata
gaccacttcgacattgagatcatgggtggccttgggccctccacggggaaggtgctgcgg
atcggcctgctgggctgcaatgccacccgcgagaatgtggaccgcgtgacggaggccctg
agggcggccctgcagcactgccccaagaagaagctgtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (9)   
   KEGG PATHWAY (7)   
   KEGG MODULE (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (7)   
   KEGG ENZYME (3)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (31)   
   RefSeq(nuc) (1)   
   GenBank (15)   
   EMBL (15)   
3D Structure (17)   
   PDB (17)   
Protein domain (2)   
   Pfam (2)   
All databases (91)   

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