KEGG   Homo sapiens (human): 1894
Entry
1894              CDS       T01001                                 
Symbol
ECT2, ARHGEF31
Name
(RefSeq) epithelial cell transforming 2
  KO
K20704  protein ECT2
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    1894 (ECT2)
Membrane trafficking [BR:hsa04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    1894 (ECT2)
SSDB
Motif
Pfam: RhoGEF ECT2_PH ECT2_BRCT0 PTCB-BRCT BRCT TopBP1_BRCT0 BRCT_2 RTT107_BRCT_5 PGBA_C
Other DBs
NCBI-GeneID: 1894
NCBI-ProteinID: NP_001245244
OMIM: 600586
HGNC: 3155
Ensembl: ENSG00000114346
UniProt: Q9H8V3
Structure
Position
3:172750726..172829265
AA seq 914 aa
MAENSVLTSTTGRTSLADSSIFDSKVTEISKENLLIGSTSYVEEEMPQIETRVILVQEAG
KQEELIKALKTIKIMEVPVIKIKESCPGKSDEKLIKSVINMDIKVGFVKMESVEEFEGLD
SPEFENVFVVTDFQDSVFNDLYKADCRVIGPPVVLNCSQKGEPLPFSCRPLYCTSMMNLV
LCFTGFRKKEELVRLVTLVHHMGGVIRKDFNSKVTHLVANCTQGEKFRVAVSLGTPIMKP
EWIYKAWERRNEQDFYAAVDDFRNEFKVPPFQDCILSFLGFSDEEKTNMEEMTEMQGGKY
LPLGDERCTHLVVEENIVKDLPFEPSKKLYVVKQEWFWGSIQMDARAGETMYLYEKANTP
ELKKSVSMLSLNTPNSNRKRRRLKETLAQLSRETDVSPFPPRKRPSAEHSLSIGSLLDIS
NTPESSINYGDTPKSCTKSSKSSTPVPSKQSARWQVAKELYQTESNYVNILATIIQLFQV
PLEEEGQRGGPILAPEEIKTIFGSIPDIFDVHTKIKDDLEDLIVNWDESKSIGDIFLKYS
KDLVKTYPPFVNFFEMSKETIIKCEKQKPRFHAFLKINQAKPECGRQSLVELLIRPVQRL
PSVALLLNDLKKHTADENPDKSTLEKAIGSLKEVMTHINEDKRKTEAQKQIFDVVYEVDG
CPANLLSSHRSLVQRVETISLGEHPCDRGEQVTLFLFNDCLEIARKRHKVIGTFRSPHGQ
TRPPASLKHIHLMPLSQIKKVLDIRETEDCHNAFALLVRPPTEQANVLLSFQMTSDELPK
ENWLKMLCRHVANTICKADAENLIYTADPESFEVNTKDMDSTLSRASRAIKKTSKKVTRA
FSFSKTPKRALRRALMTSHGSVEGRSPSSNDKHVMSRLSSTSSLAGIPSPSLVSLPSFFE
RRSHTLSRSTTHLI
NT seq 2745 nt   +upstreamnt  +downstreamnt
atggctgaaaatagtgtattaacatccactactgggaggactagcttggcagactcttcc
atttttgattctaaagttactgagatttccaaggaaaacttacttattggatctacttca
tatgtagaagaagagatgcctcagattgaaacaagagtgatattggttcaagaagctgga
aaacaagaagaacttataaaagccttaaagactattaaaataatggaagtccctgttata
aagataaaagaaagttgtcctggaaaatcggatgaaaaattaataaaaagtgttattaat
atggacattaaagtgggctttgtaaagatggagtcagtggaagaatttgaaggtttggat
tctccggaatttgaaaatgtatttgtagtcacggactttcaggattctgtctttaatgac
ctctacaaggctgattgtagagttattggaccaccagttgtattaaattgttcacaaaaa
ggagagcctttgccattttcatgtcgcccgttgtattgtacaagtatgatgaatctagta
ctatgctttactggatttaggaaaaaagaagaactagtcaggttggtgacattggtccat
cacatgggtggagttattcgaaaagactttaattcaaaagttacacatttggtggcaaat
tgtacacaaggagaaaaattcagggttgctgtgagtctaggtactccaattatgaagcca
gaatggatttataaagcttgggaaaggcggaatgaacaggatttctatgcagcagttgat
gactttagaaatgaatttaaagttcctccatttcaagattgtattttaagtttcctggga
ttttcagatgaagagaaaaccaatatggaagaaatgactgaaatgcaaggaggtaaatat
ttaccgcttggagatgaaagatgcactcaccttgtagttgaagagaatatagtaaaagat
cttccctttgaaccttcaaagaaactttatgttgtcaagcaagagtggttctggggaagc
attcaaatggatgcccgagctggagaaactatgtatttatatgaaaaggcaaatactcct
gagctcaagaaatcagtgtcaatgctttctctaaatacccctaacagcaatcgcaaacga
cgtcgtttaaaagaaacacttgctcagctttcaagagagacagacgtgtcaccatttcca
ccccgtaagcgcccatcagctgagcattccctttccatagggtcactcctagatatctcc
aacacaccagagtctagcattaactatggagacaccccaaagtcttgtactaagtcttct
aaaagctccactccagttccttcaaagcagtcagcaaggtggcaagttgcaaaagagctt
tatcaaactgaaagtaattatgttaatatattggcaacaattattcagttatttcaagta
ccattggaagaggaaggacaacgtggtggacctatccttgcaccagaggagattaagact
atttttggtagcatcccagatatctttgatgtacacactaagataaaggatgatcttgaa
gaccttatagttaattgggatgagagcaaaagcattggtgacatttttctgaaatattca
aaagatttggtaaaaacctaccctccctttgtaaacttctttgaaatgagcaaggaaaca
attattaaatgtgaaaaacagaaaccaagatttcatgcttttctcaagataaaccaagca
aaaccagaatgtggacggcagagccttgttgaacttcttatccgaccagtacagaggtta
cccagtgttgcattacttttaaatgatcttaagaagcatacagctgatgaaaatccagac
aaaagcactttagaaaaagctattggatcactgaaggaagtaatgacgcatattaatgag
gataagagaaaaacagaagctcaaaagcaaatttttgatgttgtttatgaagtagatgga
tgcccagctaatcttttatcttctcaccgaagcttagtacagcgggttgaaacaatttct
ctaggtgagcacccctgtgacagaggagaacaagtaactctcttcctcttcaatgattgc
ctagagatagcaagaaaacggcacaaggttattggcacttttaggagtcctcatggccaa
acccgacccccagcttctcttaagcatattcacctaatgcctctttctcagattaagaag
gtattggacataagagagacagaagattgccataatgcttttgccttgcttgtgaggcca
ccaacagagcaggcaaatgtgctactcagtttccagatgacatcagatgaacttccaaaa
gaaaactggctaaagatgctgtgtcgacatgtagctaacaccatttgtaaagcagatgct
gagaatcttatttatactgctgatccagaatcctttgaagtaaatacaaaagatatggac
agtacattgagtagagcatcaagagcaataaaaaagacttcaaaaaaggttacaagagca
ttctctttctccaaaactccaaaaagagctcttcgaagggctcttatgacatcccacggc
tcagtggagggaagaagtccttccagcaatgataagcatgtaatgagtcgtctttctagc
acatcatcattagcaggtatcccttctccctcccttgtcagccttccttccttctttgaa
aggagaagtcatacgttaagtagatctacaactcatttgatatga

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Ontology (2)   
   KEGG BRITE (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (84)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (82)   
DNA sequence (112)   
   RefSeq(nuc) (82)   
   GenBank (15)   
   EMBL (15)   
3D Structure (3)   
   PDB (3)   
Protein domain (9)   
   Pfam (9)   
All databases (232)   

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