KEGG   Homo sapiens (human): 192669
Entry
192669            CDS       T01001                                 
Symbol
AGO3, EIF2C3
Name
(RefSeq) argonaute RISC catalytic component 3
  KO
K11593  eukaryotic translation initiation factor 2C
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    192669 (AGO3)
   03036 Chromosome and associated proteins [BR:hsa03036]
    192669 (AGO3)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     192669 (AGO3)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Gene silencing
   RISC (RNA-induced silencing complex)
    192669 (AGO3)
   RNA interference (RNAi) pathway
    RITS (RNA-induced transcriptional silencing) complex
     192669 (AGO3)
   microRNA pathway
    RISC loading complex
     192669 (AGO3)
SSDB
Motif
Pfam: Piwi ArgoMid PAZ ArgoN ArgoL1 ArgoL2
Other DBs
NCBI-GeneID: 192669
NCBI-ProteinID: NP_079128
OMIM: 607355
HGNC: 18421
Ensembl: ENSG00000126070
UniProt: Q9H9G7 B4E1P5
Structure
Position
1:35930718..36072500
AA seq 860 aa
MEIGSAGPAGAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPR
RVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRP
FKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGR
SFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLD
IHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLE
NGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDN
QTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQ
YGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISK
DAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTL
LGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVT
HPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRF
KPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCAD
RTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADEL
QLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDP
QALAKAVQIHQDTLRTMYFA
NT seq 2583 nt   +upstreamnt  +downstreamnt
atggaaatcggctccgcaggacccgctggggcccagcccctactcatggtgcccagaaga
cctggctatggcaccatgggcaaacccattaaactgctggctaactgttttcaagttgaa
atcccaaagattgatgtctacctctatgaggtagatattaaaccagacaagtgtcctagg
agagtgaacagggaggtggttgactcaatggttcagcattttaaagtaactatatttgga
gaccgtagaccagtttatgatggaaaaagaagtctttacaccgccaatccacttcctgtg
gcaactacaggggtagatttagacgttactttacctggggaaggtggaaaagatcgacct
ttcaaggtgtcaatcaaatttgtctctcgggtgagttggcacctactgcatgaagtactg
acaggacggaccttgcctgagccactggaattagacaagccaatcagcactaaccctgtc
catgccgttgatgtggtgctacgacatctgccctccatgaaatacacacctgtggggcgt
tcatttttctccgctccagaaggatatgaccaccctctgggagggggcagggaagtgtgg
tttggattccatcagtctgttcggcctgccatgtggaaaatgatgcttaatatcgatgtt
tctgccactgccttctacaaagcacaacctgtaattcagttcatgtgtgaagttcttgat
attcataatattgatgagcaaccaagacctctgactgattctcatcgggtaaaattcacc
aaagagataaaaggtttgaaggttgaagtgactcattgtggaacaatgagacggaaatac
cgtgtttgtaatgtaacaaggaggcctgccagtcatcaaacctttcctttacagttagaa
aacggccaaactgtggagagaacagtagcgcagtatttcagagaaaagtatactcttcag
ctgaagtacccgcaccttccctgtctgcaagtcgggcaggaacagaaacacacctacctg
ccactagaagtctgtaatattgtggcagggcaacgatgtatcaagaagctaacagacaat
cagacttccactatgatcaaggcaacagcaagatctgcaccagatagacaagaggaaatt
agcagattggtaagaagtgcaaattatgaaacagatccatttgttcaggagtttcaattt
aaagttcgggatgaaatggctcatgtaactggacgcgtacttccagcacctatgctccag
tatggaggacggaatcggacagtagcaacaccgagccatggagtatgggacatgcgaggg
aaacaattccacacaggagttgaaatcaaaatgtgggctatcgcttgttttgccacacag
aggcagtgcagagaagaaatattgaagggtttcacagaccagctgcgtaagatttctaag
gatgcagggatgcccatccagggccagccatgcttctgcaaatatgcacagggggcagac
agcgtagagcccatgttccggcatctcaagaacacatattctggcctacagcttattatc
gtcatcctgccggggaagacaccagtgtatgcggaagtgaaacgtgtaggagacacactt
ttgggtatggctacacaatgtgttcaagtcaagaatgtaataaaaacatctcctcaaact
ctgtcaaacttgtgcctaaagataaatgttaaactcggagggatcaataatattcttgta
cctcatcaaagaccttctgtgttccagcaaccagtgatctttttgggagccgatgtcact
catccacctgctggtgatggaaagaagccttctattgctgctgttgtaggtagtatggat
gcacacccaagcagatactgtgccacagtaagagttcagagaccccgacaggagatcatc
caggacttggcctccatggtccgggaacttcttattcaattttataagtcaactcggttc
aagcctactcgtatcatcttttatcgggatggtgtttcagaggggcagtttaggcaggta
ttatattatgaactactagcaattcgagaagcctgcatcagtttggagaaagactatcaa
cctggaataacctacattgtagttcagaagagacatcacactcgattattttgtgctgat
aggacagaaagggttggaagaagtggcaatatcccagctggaacaacagttgatacagac
attacacacccatatgagttcgatttttacctctgtagccatgctggaatacagggtacc
agtcgtccttcacactatcatgttttatgggatgataactgctttactgcagatgaactt
cagctgctaacttaccagctctgccacacttacgtacgctgtacacgatctgtttctata
cctgcaccagcgtattatgctcacctggtagcatttagagccagatatcatcttgtggac
aaagaacatgacagtgctgaaggaagtcacgtttcaggacaaagcaatgggcgagatcca
caagctcttgccaaggctgtacagattcaccaagataccttacgcacaatgtacttcgct
taa

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Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (19)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (16)   
DNA sequence (40)   
   RefSeq(nuc) (16)   
   GenBank (12)   
   EMBL (12)   
3D Structure (1)   
   PDB (1)   
Protein domain (6)   
   Pfam (6)   
All databases (85)   

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