KEGG   Homo sapiens (human): 1974
Entry
1974              CDS       T01001                                 
Symbol
EIF4A2, BM-010, DDX2B, EIF4A, EIF4F, NEDHSS, eIF-4A-II, eIF4A-II
Name
(RefSeq) eukaryotic translation initiation factor 4A2
  KO
K03257  translation initiation factor 4A
Organism
hsa  Homo sapiens (human)
Disease
H02397  Neurodevelopmental disorder with movement abnormalities or hypotonia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    1974 (EIF4A2)
   03012 Translation factors [BR:hsa03012]
    1974 (EIF4A2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    1974 (EIF4A2)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Transport factors
    eIF4F and regulatory proteins
     1974 (EIF4A2)
   mRNA cycle factors
    Stress granule specific factors
     1974 (EIF4A2)
Translation factors [BR:hsa03012]
 Eukaryotic type
  Initiation factors
   eIF-4
    1974 (EIF4A2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   1974 (EIF4A2)
  Exosomal proteins of bladder cancer cells
   1974 (EIF4A2)
SSDB
Motif
Pfam: DEAD Helicase_C ResIII AAA_19 UvrD-helicase AAA_30 AAA_22 Flavi_DEAD
Other DBs
NCBI-GeneID: 1974
NCBI-ProteinID: NP_001958
OMIM: 601102
HGNC: 3284
Ensembl: ENSG00000156976
UniProt: Q14240
Structure
Position
3:186783577..186789897
AA seq 407 aa
MSGGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQ
QRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKV
ILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMF
VLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKE
ELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTV
SALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHR
IGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI
NT seq 1224 nt   +upstreamnt  +downstreamnt
atgtctggtggctccgcggattataacagagaacatggcggcccagagggaatggacccc
gatggtgtcatcgagagcaactggaatgagattgttgataactttgatgatatgaattta
aaggagtctctccttcgtggcatctatgcttacggttttgagaagccttccgctattcag
cagagagctattattccctgtattaaagggtatgatgtgattgctcaagctcagtcaggt
actggcaagacagccacatttgctatttccatcctgcaacagttggagattgagttcaag
gagacccaagcactagtattggcccccaccagagaactggctcaacagatccaaaaggta
attctggcacttggagactatatgggagccacttgtcatgcctgcattggtggaacaaat
gttcgaaatgaaatgcaaaaactgcaggctgaagcaccacatattgttgttggtacaccc
gggagagtgtttgatatgttaaacagaagatacctttctccaaaatggatcaaaatgttt
gttttggatgaagcagatgaaatgttgagccgtggttttaaggatcaaatctatgagatt
ttccaaaaactaaacacaagtattcaggttgtgttgctttctgccacaatgccaactgat
gtgttggaagtgaccaaaaaattcatgagagatccaattcgaattctggtgaaaaaggaa
gaattgacccttgaaggaatcaaacagttttatattaatgttgagagagaggaatggaag
ttggatacactttgtgacttgtacgagacactgaccattacacaggctgttatttttctc
aatacgaggcgcaaggtggactggctgactgagaagatgcatgccagagacttcacagtt
tctgctctgcatggtgacatggaccagaaggagagagatgttatcatgagggaattccgg
tcagggtcaagtcgtgttctgatcactactgacttgttggctcgcgggattgatgtgcaa
caagtgtctttggttataaattatgatctacctaccaatcgtgaaaactatattcacaga
attggcagagggggtcgatttgggaggaaaggtgtggctataaactttgttactgaagaa
gacaagaggattcttcgtgacattgagactttctacaatactacagtggaggagatgccc
atgaatgtggctgaccttatttaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (109)   
   KEGG ORTHOLOGY (1)   
   RefGene (83)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (20)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (39)   
   RefSeq(nuc) (1)   
   GenBank (19)   
   EMBL (19)   
3D Structure (1)   
   PDB (1)   
Protein domain (8)   
   Pfam (8)   
All databases (168)   

Download RDF
DBGET integrated database retrieval system