KEGG   Homo sapiens (human): 2022
Entry
2022              CDS       T01001                                 
Symbol
ENG, END, HHT1, ORW1, ORW
Name
(RefSeq) endoglin
  KO
K06526  endoglin
Organism
hsa  Homo sapiens (human)
Network
nt06507  TGFB signaling
  Element
N01462  BMP9/10 signaling pathway, BMP9/10 coreceptor
Disease
H00533  Hereditary hemorrhagic telangiectasia
Drug target
Carotuximab: D11260
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    2022 (ENG)
CD molecules [BR:hsa04090]
 Proteins
  2022 (ENG)
SSDB
Motif
Pfam: TraL
Other DBs
NCBI-GeneID: 2022
NCBI-ProteinID: NP_001108225
OMIM: 131195
HGNC: 3349
Ensembl: ENSG00000106991
UniProt: P17813 Q96CG0
Structure
Position
9:complement(127815016..127854658)
AA seq 658 aa
MDRGTLPLAVALLLASCSLSPTSLAETVHCDLQPVGPERGEVTYTTSQVSKGCVAQAPNA
ILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQALGIPLHLAY
NSSLVTFQEPPGVNTTELPSFPKTQILEWAAERGPITSAAELNDPQSILLRLGQAQGSLS
FCMLEASQDMGRTLEWRPRTPALVRGCHLEGVAGHKEAHILRVLPGHSAGPRTVTVKVEL
SCAPGDLDAVLILQGPPYVSWLIDANHNMQIWTTGEYSFKIFPEKNIRGFKLPDTPQGLL
GEARMLNASIVASFVELPLASIVSLHASSCGGRLQTSPAPIQTTPPKDTCSPELLMSLIQ
TKCADDAMTLVLKKELVAHLKCTITGLTFWDPSCEAEDRGDKFVLRSAYSSCGMQVSASM
ISNEAVVNILSSSSPQRKKVHCLNMDSLSFQLGLYLSPHFLQASNTIEPGQQSFVQVRVS
PSVSEFLLQLDSCHLDLGPEGGTVELIQGRAAKGNCVSLLSPSPEGDPRFSFLLHFYTVP
IPKTGTLSCTVALRPKTGSQDQEVHRTVFMRLNIISPDLSGCTSKGLVLPAVLGITFGAF
LIGALLTAALWYIYSHTRSPSKREPVVAVAAPASSESSSTNHSIGSTQSTPCSTSSMA
NT seq 1977 nt   +upstreamnt  +downstreamnt
atggaccgcggcacgctccctctggctgttgccctgctgctggccagctgcagcctcagc
cccacaagtcttgcagaaacagtccattgtgaccttcagcctgtgggccccgagaggggc
gaggtgacatataccactagccaggtctcgaagggctgcgtggctcaggcccccaatgcc
atccttgaagtccatgtcctcttcctggagttcccaacgggcccgtcacagctggagctg
actctccaggcatccaagcaaaatggcacctggccccgagaggtgcttctggtcctcagt
gtaaacagcagtgtcttcctgcatctccaggccctgggaatcccactgcacttggcctac
aattccagcctggtcaccttccaagagcccccgggggtcaacaccacagagctgccatcc
ttccccaagacccagatccttgagtgggcagctgagaggggccccatcacctctgctgct
gagctgaatgacccccagagcatcctcctccgactgggccaagcccaggggtcactgtcc
ttctgcatgctggaagccagccaggacatgggccgcacgctcgagtggcggccgcgtact
ccagccttggtccggggctgccacttggaaggcgtggccggccacaaggaggcgcacatc
ctgagggtcctgccgggccactcggccgggccccggacggtgacggtgaaggtggaactg
agctgcgcacccggggatctcgatgccgtcctcatcctgcagggtcccccctacgtgtcc
tggctcatcgacgccaaccacaacatgcagatctggaccactggagaatactccttcaag
atctttccagagaaaaacattcgtggcttcaagctcccagacacacctcaaggcctcctg
ggggaggcccggatgctcaatgccagcattgtggcatccttcgtggagctaccgctggcc
agcattgtctcacttcatgcctccagctgcggtggtaggctgcagacctcacccgcaccg
atccagaccactcctcccaaggacacttgtagcccggagctgctcatgtccttgatccag
acaaagtgtgccgacgacgccatgaccctggtactaaagaaagagcttgttgcgcatttg
aagtgcaccatcacgggcctgaccttctgggaccccagctgtgaggcagaggacaggggt
gacaagtttgtcttgcgcagtgcttactccagctgtggcatgcaggtgtcagcaagtatg
atcagcaatgaggcggtggtcaatatcctgtcgagctcatcaccacagcggaaaaaggtg
cactgcctcaacatggacagcctctctttccagctgggcctctacctcagcccacacttc
ctccaggcctccaacaccatcgagccggggcagcagagctttgtgcaggtcagagtgtcc
ccatccgtctccgagttcctgctccagttagacagctgccacctggacttggggcctgag
ggaggcaccgtggaactcatccagggccgggcggccaagggcaactgtgtgagcctgctg
tccccaagccccgagggtgacccgcgcttcagcttcctcctccacttctacacagtaccc
atacccaaaaccggcaccctcagctgcacggtagccctgcgtcccaagaccgggtctcaa
gaccaggaagtccataggactgtcttcatgcgcttgaacatcatcagccctgacctgtct
ggttgcacaagcaaaggcctcgtcctgcccgccgtgctgggcatcacctttggtgccttc
ctcatcggggccctgctcactgctgcactctggtacatctactcgcacacgcgttccccc
agcaagcgggagcccgtggtggcggtggctgccccggcctcctcggagagcagcagcacc
aaccacagcatcgggagcacccagagcaccccctgctccaccagcagcatggcatag

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Ontology (2)   
   KEGG BRITE (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (31)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (14)   
   OC (1)   
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (34)   
   RefSeq(nuc) (4)   
   GenBank (15)   
   EMBL (15)   
3D Structure (3)   
   PDB (3)   
Protein domain (1)   
   Pfam (1)   
All databases (85)   

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