KEGG   Homo sapiens (human): 204
Entry
204               CDS       T01001                                 
Symbol
AK2, ADK2
Name
(RefSeq) adenylate kinase 2
  KO
K00939  adenylate kinase [EC:2.7.4.3]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00230  Purine metabolism
hsa00730  Thiamine metabolism
hsa01100  Metabolic pathways
hsa01232  Nucleotide metabolism
hsa01240  Biosynthesis of cofactors
Module
hsa_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
Disease
H00092  T-B-Severe combined immunodeficiency
H01128  Reticular dysgenesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    204 (AK2)
  09108 Metabolism of cofactors and vitamins
   00730 Thiamine metabolism
    204 (AK2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    204 (AK2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.4  Phosphotransferases with a phosphate group as acceptor
    2.7.4.3  adenylate kinase
     204 (AK2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   204 (AK2)
SSDB
Motif
Pfam: ADK AAA_17 ADK_lid AAA_33 AAA_18 Cytidylate_kin AAA_28
Other DBs
NCBI-GeneID: 204
NCBI-ProteinID: NP_001616
OMIM: 103020
HGNC: 362
Ensembl: ENSG00000004455
UniProt: P54819 A0A140VK93
Structure
Position
1:complement(33007940..33036883)
AA seq 239 aa
MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSEL
GKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKE
KLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNE
KALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKATCKDLVMFI
NT seq 720 nt   +upstreamnt  +downstreamnt
atggctcccagcgtgccagcggcagaacccgagtatcctaaaggcatccgggccgtgctg
ctggggcctcccggggccggtaaagggacccaggcacccagattggctgaaaacttctgt
gtctgccatttagctactggggacatgctgagggccatggtggcttctggctcagagcta
ggaaaaaagctgaaggcaactatggatgctgggaaactggtgagtgatgaaatggtagtg
gagctcattgagaagaatttggagacccccttgtgcaaaaatggttttcttctggatggc
ttccctcggactgtgaggcaggcagaaatgctcgatgacctcatggagaagaggaaagag
aagcttgattctgtgattgaattcagcatcccagactctctgctgatccgaagaatcaca
ggaaggctgattcaccccaagagtggccgttcctaccacgaggagttcaaccctccaaaa
gagcccatgaaagatgacatcaccggggaacccttgatccgtcgatcagatgataatgaa
aaggccttgaaaatccgcctgcaagcctaccacactcaaaccaccccactcatagagtac
tacaggaaacgggggatccactccgccatcgatgcatcccagacccccgatgtcgtgttc
gcaagcatcctagcagccttctccaaagccacatgtaaagacttggttatgtttatctaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Disease (4)   
   KEGG DISEASE (2)   
   OMIM (2)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (11)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (68)   
   RefSeq(nuc) (10)   
   GenBank (29)   
   EMBL (29)   
3D Structure (1)   
   PDB (1)   
Protein domain (7)   
   Pfam (7)   
All databases (127)   

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