KEGG   Homo sapiens (human): 2051
Entry
2051              CDS       T01001                                 
Symbol
EPHB6, HEP
Name
(RefSeq) EPH receptor B6
  KO
K05114  Eph receptor B6 [EC:2.7.10.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    2051 (EPHB6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    2051 (EPHB6)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     2051 (EPHB6)
Protein kinases [BR:hsa01001]
 Receptor tyrosine kinases (RTK)
  EPH family [OT]
   2051 (EPHB6)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Ephrin_lbd Pkinase fn3 EphA2_TM SAM_2 SAM_1 Ephrin_rec_like Pur_ac_phosph_N CRLF2-like_D2 Phage_holin_5_1
Other DBs
NCBI-GeneID: 2051
NCBI-ProteinID: NP_004436
OMIM: 602757
HGNC: 3396
Ensembl: ENSG00000106123
UniProt: O15197 F8WCM8
Structure
Position
7:142855076..142871093
AA seq 1022 aa
MATEGAAQLGNRVAGMVCSLWVLLLVSSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVS
VLDDQRRLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVS
GGTCRETFTLYYRQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSSAAW
AVGPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSF
ASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGC
RCQPGYQPARGDKACQACPRGLYKASAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASS
DPPEAPCTGPPSAPQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASG
GGGTCHRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAI
NVSTSHEVPSAVPVVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLT
SETNTATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGS
ILGALAFLLLAAITVLAVVFQRKRRGTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIR
ELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGR
AAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGV
AAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLGHSPQGPSCLLRWAAPEVIAHGKHT
TSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQ
KDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSA
IGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSV
EV
NT seq 3069 nt   +upstreamnt  +downstreamnt
atggctactgaaggggctgcccagttagggaacagagtggcgggcatggtgtgtagccta
tgggtgctgctcctggtgtcttcagttctggctctggaagaggtattgctggacaccacc
ggagagacatctgagattggctggctcacctacccaccaggggggtgggacgaggtgagt
gttctggacgaccagcgacgcctgactcggacctttgaggcatgtcatgtggcaggggcc
cctccaggcaccgggcaggacaattggttgcagacacactttgtggagcggcgcggggcc
cagagggcgcacattcgactccacttctctgtgcgggcatgctccagcctgggtgtgagc
ggcggcacctgccgggagaccttcaccctttactaccgtcaggctgaggagcccgacagc
cctgacagcgtttcctcctggcacctcaaacgctggaccaaggtggacacaattgcagca
gacgagagctttccctcctcctcctcctcctcctcctcctcttcttcctctgcagcgtgg
gctgtgggaccccacggggctgggcagcgggctggactgcaactgaacgtcaaagagcgg
agctttgggcctctcacccaacgcggcttctacgtggccttccaggacacgggggcctgc
ctggccctggtcgctgtcaggctcttctcctacacctgccctgccgtgctccgatccttt
gcttcctttccagagacgcaggccagtggggctgggggggcctccctggtggcagctgtg
ggcacctgtgtggctcatgcagagccagaggaggatggagtagggggccaggcaggaggc
agcccccccaggctgcactgcaacggggagggcaagtggatggtagctgtcgggggctgc
cgctgccagcctggataccaaccagcacgaggagacaaggcctgccaagcctgcccacgg
gggctctataaggcttctgctgggaatgctccctgctcaccatgccctgcccgcagtcac
gctcccaacccagcagcccccgtttgcccctgcctggagggcttctaccgggccagttcc
gacccaccagaggccccctgcactggtcctccatcggctccccaggagctttggtttgag
gtgcaaggctcagcactcatgctacactggcgcctgcctcgggagctggggggtcgaggg
gacctgctcttcaatgtcgtgtgcaaggagtgtgaaggccgccaggaacctgccagcggt
ggtgggggcacttgtcaccgctgcagggatgaggtccacttcgaccctcgccagagaggc
ctgactgagagccgagtgttagtggggggactccgggcacacgtaccctacatcttagag
gtgcaggctgttaatggggtgtctgagctcagccctgaccctcctcaggctgcagccatc
aatgtcagcaccagccatgaagtgccctctgctgtccctgtggtgcaccaggtgagccgg
gcatccaacagcatcacggtgtcctggccgcagcccgaccagaccaatgggaacatcctg
gactatcagctccgctactatgaccaggcagaagacgaatcccactccttcaccctgacc
agcgagaccaacactgccaccgtgacacagctgagccctggccacatctatggtttccag
gtgcgggcccggactgctgccggccacggcccctacgggggcaaagtctatttccagaca
cttcctcaaggggagctgtcttcccagcttccagaaagactctccttggtgatcggctcc
atcctgggggctttggccttcctcctgctggcagccatcaccgtgctggcggtcgtcttc
cagcggaagcggcgtgggactggctacacagagcagctgcagcaatacagcagcccagga
ctcggggtgaagtattacatcgacccctccacctacgaggacccctgtcaggccatccga
gaacttgcccgggaagtcgatcctgcttatatcaagattgaggaggtcattgggacaggc
tcttttggagaagtgcgccagggccgcctgcagccacggggacggagggagcagactgtg
gccatccaggccctgtgggccgggggcgccgaaagcctgcagatgaccttcctgggccgg
gccgcagtgctgggtcagttccagcaccccaacatcctgcggctggagggcgtggtcacc
aagagccgacccctcatggtgctgacggagttcatggagcttggccccctggacagcttc
ctcaggcagcgggagggccagttcagcagcctgcagctggtggccatgcagcggggagtg
gctgctgccatgcagtacctgtccagctttgccttcgtccatcgctcgctgtctgcccac
agcgtgctggtgaatagccacttggtgtgcaaggtggcccgtcttggccacagtcctcag
ggcccaagttgtttgcttcgctgggcagccccagaggtcattgcacatggaaagcataca
acatccagtgatgtctggagctttgggatactcatgtgggaagtgatgagttatggagaa
cggccttactgggacatgagtgagcaggaggtactaaatgcaatagagcaggagttccgg
ctgcccccgcctccaggctgtcctcctggattacatctacttatgttggacacttggcag
aaggaccgtgcccggcggcctcattttgaccagctggtggctgcatttgacaagatgatc
cgcaagccagataccctgcaggctggcggggacccaggggaaaggccttcccaggccctt
ctgacccctgtggccctggactttccttgtctggactcaccccaggcctggctttcagcc
attggactggagtgctaccaggacaacttctccaagtttggcctctgtaccttcagtgat
gtggctcagctcagcctagaagacctgcctgccctgggcatcaccctggctggccaccag
aagaagctgctgcaccacatccagctccttcagcaacacctgaggcagcagggctcagtg
gaggtctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (30)   
   KEGG ORTHOLOGY (1)   
   RefGene (23)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (29)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (26)   
DNA sequence (61)   
   RefSeq(nuc) (27)   
   GenBank (17)   
   EMBL (17)   
3D Structure (1)   
   PDB (1)   
Protein domain (11)   
   Pfam (11)   
All databases (139)   

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