KEGG   Homo sapiens (human): 221264
Entry
221264            CDS       T01001                                 
Symbol
AK9, AK_9, AKD1, AKD2, C6orf199, C6orf224, SPGF89, dJ70A9.1
Name
(RefSeq) adenylate kinase 9
  KO
K18533  adenylate/nucleoside-diphosphate kinase [EC:2.7.4.3 2.7.4.6]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00230  Purine metabolism
hsa00240  Pyrimidine metabolism
hsa01100  Metabolic pathways
hsa01232  Nucleotide metabolism
hsa01240  Biosynthesis of cofactors
Module
hsa_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
hsa_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP
hsa_M00052  Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP
hsa_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
hsa_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Disease
H01282  Spermatogenic failure
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    221264 (AK9)
   00240 Pyrimidine metabolism
    221264 (AK9)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.4  Phosphotransferases with a phosphate group as acceptor
    2.7.4.3  adenylate kinase
     221264 (AK9)
    2.7.4.6  nucleoside-diphosphate kinase
     221264 (AK9)
SSDB
Motif
Pfam: ADK AAA_17 AAA_18 AAA AAA_22 nSTAND3 AAA_28 AAA_24 AAA_14 YHS AAA_5 AAA_16 Zeta_toxin NACHT AAA_33 NTPase_1 Cytidylate_kin ABC_tran FAP206 RuvB_N ATPase_2 G-alpha NB-ARC AAA_19 AAA_30 SKI KTI12 SRPRB ZZ Hydin_ADK ResIII
Other DBs
NCBI-GeneID: 221264
NCBI-ProteinID: NP_001138600
OMIM: 615358
HGNC: 33814
Ensembl: ENSG00000155085
UniProt: Q5TCS8
Position
6:complement(109492855..109691202)
AA seq 1911 aa
MTSQEKTEEYPFADIFDEDETERNFLLSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVE
ALPILEEQIAAETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSL
SQDAMTTLQQIELIKNLNLKPDVIINIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEV
IENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENI
VKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKRAAILTKLQG
AEEEINDTMENDELFRTLASYKLIAPRYRWQRSKWGRTCPVNLKDGNIYSGLPDYSVSFL
GKIYCLSSEEALKPFLLNPRPYLLPPMPGPPCKVFILGPQYSGKTTLCNMLAENYKGKVV
DYAQLVQPRFDKARETLVENTIAEATAAAIKVVKEKLLRELQARKQAETALREFQRQYEK
MEFGVFPMEATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKE
TGETFTFKRHSQDASQDVKLYSDTAPTEDLIEEVTADHPEVVTMIEETIKMSQDINFEQP
YEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKKGIIPDLVIYL
SDTENNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRR
LLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPE
AVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFII
LWKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDY
QTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREK
IYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHI
QFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQ
LTEEEEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRG
FFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAE
LILERDKKRRENVVRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAI
ERLRGELGEKFEADTHNLQIIQDELERYLIPIISINGARRNHIVQYTLNMKLKPLVENRA
SIFEKCHPIPAPLAQKMLTFTYKYISSFGYWDPVKLSEGETIKPVENAENPIYPVIHRQY
IYFLSSKETKEKFMKNPIKYIRQPKPKPTVPIRIIIVGPPKSGKTTVAKKITSEYGLKHL
SIGGALRYVLNNHPETELALMLNWHLHKGMTAPDELAIQALELSLMESVCNTAGVVIDGY
PVTKHQMNLLEARSIIPMVIFELSVPSKEIFKRLLLEKENEQRLPYPLHNSAQIVAVNNV
KYRKNIGEIRQYYQEQHQNWYVIDGFHSKWWVWNEVIKNVQMVNKYMQTYLERIKAGKAA
CIDKLCITPQELLSRLGEFEQFCPVSLAESQELFDCSATDSLEFAAEFRGHYYKMSSQEK
LNKFLENPELYVPPLAPHPLPSADMIPKRLTLSELKSRFPKCAELQGYCPVTYKDGNQRY
EALVPGSINYALEYHNRIYICENKEKLQKFLRSPLKYWEQKLPHKLPPLREPILLTSLPL
PGYLEQGIATSLIKAMNAAGCLKPKFPFLSIRRSALLYIALHLKAFNPKGSEYTRKKYKK
KMEQFMESCELITYLGAKMTRKYKEPQFRAIDFDHKLKTFLSLRNIDPING
NT seq 5736 nt   +upstreamnt  +downstreamnt
atgacttctcaagagaagacagaagagtatccttttgcagatatatttgatgaagatgaa
actgaaaggaattttttgttgtccaaacctgtttgctttgttgtatttgggaaaccaggt
gttgggaaaacaacattagcccgttacataacacaggcatggaaatgtattcgtgttgaa
gctttgccaattttagaagaacagattgctgctgaaaccgaatcaggagttatgttgcaa
tcaatgttgatcagcggtcaaagcattccagatgaacttgtcataaagctaatgttggag
aagctcaactccccagaagtctgtcactttggttatattatcactgaaataccatcactt
tcacaggatgccatgactaccttacagcaaatagaattaattaaaaacttaaacctgaaa
cctgatgttataatcaatataaagtgtcctgactatgatttgtgccagagaatttctggg
caaagacagcacaataatacgggatacatatacagtagagaccagtgggatcctgaagtc
attgagaatcataggaaaaagaagaaagaagcccaaaaggacggaaaaggagaagaggaa
gaagaggaagaagagcaagaagaagaagaggcatttattgccgaaatgcagatggtggct
gaaattcttcatcatctagttcagaggcctgaagattatttggaaaatgttgaaaacatt
gttaagctttataaggaaacaattctccaaactttagaagaagtaatggctgaacacaat
ccccagtatctcattgagctaaatggaaataaaccagcagaggagctctttatgattgtt
atggatcgacttaaatatctgaacctaaaaagagcagctattctaaccaaacttcagggt
gcagaggaagaaattaatgacacaatggaaaatgatgagctatttcgtactcttgcatct
tataaacttattgcaccaagatacagatggcaaagaagtaaatggggacgtacatgtcct
gtgaatttaaaagatggtaacatttattcaggattaccagattattctgtgagttttcta
ggtaaaatctactgtctttcatcagaagaagcattaaaaccatttttgttgaacccacgt
ccctatctgcttccacctatgccaggaccaccatgtaaagtattcatacttggacctcaa
tattcagggaaaacaacactttgcaatatgcttgcagaaaattacaaaggaaaggtagtc
gactatgcccaacttgttcagccacgttttgataaagcccgtgaaacattagtagaaaat
accatagctgaggccactgcagcagcaattaaagttgtgaaagaaaagcttctcagggaa
ctgcaagctagaaaacaagctgaaacagctttaagagaatttcaaaggcaatatgaaaaa
atggagtttggagtattcccaatggaggcaacacactcatcaattgatgaagaagggtac
attcaaggctcccaaagggacagaggcagctctttagtggacaccgaagaagccaaaaca
aagtcagaaaatgtcctccatgatcaagctgctaaagttgataaagatgatggaaaagaa
actggtgaaacattcacatttaaaaggcattctcaagatgctagtcaagatgtaaagttg
tattcagatacagccccaacagaagacttgatagaagaggtaactgcagatcatccagag
gttgtgaccatgattgaagagactataaaaatgtcacaggatataaactttgaacagcca
tatgaaaaacatgctgaaatcttacaggaagtccttggagaggtaatggaagaaaacaag
gataggtttcctggtgccccaaaatatggaggctggattgtggacaactgccctattgta
aaagaattgtggatggccttaatcaagaaaggaattatacctgatttggtcatctattta
tcagatacagaaaacaatggaaaatgtttatttaatagaatatatttacagaagaaatct
gaaattgactctaagattttagaaagattattagaagaactacaaaagaaaaaaaaagaa
gaagaagaagcaagaaaagccacagaagaggaattgagactcgaagaagaaaatcgaagg
ctactggaacttatgaaagtgaaggcaaaagaagctgaagagactgataatgaggatgaa
gaggagattgaaggtgatgagttggaagttcacgaagagcctgaggcatctcacgatacc
cgagggtcatggttacctgaggagtttgaagcatctgaggtccctgaaactgagcctgaa
gcagtatctgagcctatcgaggaaactacagtggaaacagaaatcccaaaaggatccaaa
gagggcctggaaattgaaaaattatctgaaacagttgtactacctgagtttccagaagac
tcttatcctgatgttcccgaaatggagccatttaaagagaagattggttctttcatcatc
ctctggaaacagctagaagcaacaattagtgaggcttacattaaaattttaaacttggag
attgctgacagaactccacaggaattacttcaaaaagtagttgagactatggaaaaacca
tttcaatatactgcatgggagttaactggggaagattatgaggaagaaacagaagactac
cagactgaagcagaggttgatgaggagctagaggaagaggaagaggaagagggtgaagat
aaaatgaaggagagaaagaggcatttgggagacacaaaacacttttgtccggtggtcctc
aaagaaaacttcatcctgcaaccaggaaacacagaagaagcagccaagtatcgagaaaag
atctactacttttcaagtgctgaggctaaagaaaagtttttggagcatcctgaggattat
gtggctcatgaagaaccattgaaggctcctccattaagaatatgccttgtcggcccccag
ggctctggcaaaactatgtgtggaagacagttggcagaaaaattaaacatttttcacatt
cagtttgaagaagttcttcaagaaaaactactactcaaaactgaaaagaaagtgggacct
gaatttgaggaagattctgagaacgagcaagctgccaaacaagaacttgaagagcttgca
attcaggccaatgtcaaagttgaggaagaaaatacaaaaaagcagcttccagaagtacaa
cttacagaagaagaagaagtaatcaaatcaagtctaatggaaaatgagcccttgcctcct
gaaattcttgaagtaattctttctgagtggtggcttaaggaaccaatacgttccacaggt
tttatattagatggtttcccacgatatccagaagaggcccagtttttgggagatcgtgga
tttttcccagatgcagctgtttttatacaagttgatgatcaagatatttttgatcgcctc
cttcctgcccaaattgaaaagtggaaactaaaacaaaagaagaaattagaaaggaagaaa
ctgatcaaagacatgaaggcaaaaatcagggttgatacgattgctaaaagaagggctgaa
cttatattagagagagataaaaaaaggagggagaatgttgttagagatgatgaagagatt
agtgaggaagaacttgaagaagacaatgatgatattgaaaacatccttgaagatgagttt
ccaaaagatgaggaagagatgagtggcgaggaagatgaagaacaggaaactgatgcaatt
gagcgcctgagaggtgaactaggagaaaaatttgaagcagatacacataatttacaaata
atacaggatgaacttgagaggtatttgataccaataatttccattaatggagctcggaga
aatcacattgtacaatatacattgaatatgaaactgaaaccactggtggaaaatcgtgca
agcatttttgagaaatgtcatccaataccagcaccccttgcccagaaaatgctcaccttt
acctacaagtatataagctcattcggctattgggaccctgtaaagctaagtgaaggagag
acaatcaagccagttgaaaatgcagagaatccaatttatcctgtaatccatcgtcagtat
atttattttttatctagtaaagaaacaaaagaaaaatttatgaagaacccaatcaaatat
atccgccaacccaaacctaagcctactgtgcccattaggattataattgtggggcctcca
aaatctgggaaaactacagttgccaaaaaaattacaagtgaatatgggttaaagcattta
tcaataggaggagctttgcgttatgtactaaacaatcacccggaaacagagctggcactt
atgttaaattggcatcttcataaaggaatgacagcacctgatgaactggctattcaagcc
ttagaactttctctgatggaaagtgtgtgcaatactgcaggtgttgtcatcgatggatat
cctgtaactaaacatcaaatgaatctcttggaagctaggtcaatcattcccatggtcatc
tttgaattgagtgtgccttccaaggagattttcaaaagattgctcctagaaaaagaaaat
gaacaaagattgccttatccattgcacaatagtgcacaaattgtagctgtcaataatgta
aagtatcgcaaaaatattggtgagattaggcaatattatcaagaacagcatcagaactgg
tatgtgattgatggatttcacagcaaatggtgggtatggaatgaagtcattaagaatgtt
caaatggtgaataaatacatgcagacatacctggaaagaataaaagcaggaaaagctgcc
tgcattgacaagttatgtatcacacctcaagagctgctttctcgcctgggagaatttgaa
cagttctgccctgtcagcctggcagaatcccaggaattatttgattgctctgcaactgac
tccttggaatttgcagcagagttcagggggcactactataaaatgagttctcaggaaaaa
ctgaataaattcttggagaacccagaattgtacgtgcctcccttagcacctcatccactc
ccatctgctgacatgatccccaaaagactgacactgtcagagctgaagagtcgattccct
aagtgtgcggagctccagggctactgtccagtgacctataaggatggaaaccaaagatat
gaagctctagtacctggtagcattaactatgctttagaatatcataatcgtatatatatt
tgtgagaacaaagaaaaactccagaaatttttgaggtcgccactgaaatactgggaacag
aagcttccacacaagcttcccccattaagggaaccgatacttcttactagtcttcctttg
cctggatatctggaacagggtattgcaacttctctaattaaagcaatgaatgcagcggga
tgcttaaagcccaagttcccctttttaagtataaggagatctgcactgctatatatagca
cttcatctcaaagcatttaatcccaaaggttccgaatacacaagaaaaaagtataagaag
aagatggagcagtttatggagagttgtgaactcataacatacttgggtgccaagatgacc
agaaaatacaaggaacctcagttcagagccattgactttgatcataagttaaagaccttt
ctctctctcagaaatatagacccaattaatgggtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (5)   
   KEGG MODULE (5)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (26)   
   KEGG COMPOUND (26)   
Chemical reaction (16)   
   KEGG ENZYME (2)   
   KEGG REACTION (14)   
Genome (1)   
   KEGG GENOME (1)   
Gene (48)   
   KEGG ORTHOLOGY (1)   
   RefGene (40)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (42)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (40)   
DNA sequence (70)   
   RefSeq(nuc) (44)   
   GenBank (13)   
   EMBL (13)   
Protein domain (31)   
   Pfam (31)   
All databases (249)   

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