KEGG   Homo sapiens (human): 2266
Entry
2266              CDS       T01001                                 
Symbol
FGG
Name
(RefSeq) fibrinogen gamma chain
  KO
K03905  fibrinogen gamma chain
Organism
hsa  Homo sapiens (human)
Pathway
hsa04610  Complement and coagulation cascades
hsa04611  Platelet activation
hsa04613  Neutrophil extracellular trap formation
hsa05150  Staphylococcus aureus infection
hsa05171  Coronavirus disease - COVID-19
Network
nt06171  SARS coronavirus 2 (SARS-CoV-2)
nt06514  Coagulation cascade
  Element
N01502  Lectin pathway of coagulation cascade, fibrinogen to fibrin
N01513  Common pathway of coagulation cascade, fibrinogen to fibrin
Disease
H00222  Afibrinogenemia
H00223  Inherited thrombophilia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    2266 (FGG)
   04611 Platelet activation
    2266 (FGG)
   04613 Neutrophil extracellular trap formation
    2266 (FGG)
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    2266 (FGG)
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    2266 (FGG)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    2266 (FGG)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    2266 (FGG)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   2266 (FGG)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate / Heparin
  Extracellular matrix molecules
   2266 (FGG)
 Hyaluronan
  Extracellular matrix or blood plasma proteins
   2266 (FGG)
SSDB
Motif
Pfam: Fibrinogen_C Fib_alpha TMF_DNA_bd
Other DBs
NCBI-GeneID: 2266
NCBI-ProteinID: NP_068656
OMIM: 134850
HGNC: 3694
Ensembl: ENSG00000171557
CPD: C00290
UniProt: P02679
Structure
Position
4:complement(154604136..154612656)
AA seq 453 aa
MSWSLHPRNLILYFYALLFLSSTCVAYVATRDNCCILDERFGSYCPTTCGIADFLSTYQT
KVDKDLQSLEDILHQVENKTSEVKQLIKAIQLTYNPDESSKPNMIDAATLKSRKMLEEIM
KYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQ
DIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEG
FGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKY
RLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGW
WMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTI
GEGQQHHLGGAKQVRPEHPAETEYDSLYPEDDL
NT seq 1362 nt   +upstreamnt  +downstreamnt
atgagttggtccttgcacccccggaatttaattctctacttctatgctcttttatttctc
tcttcaacatgtgtagcatatgttgctaccagagacaactgctgcatcttagatgaaaga
ttcggtagttattgtccaactacctgtggcattgcagatttcctgtctacttatcaaacc
aaagtagacaaggatctacagtctttggaagacatcttacatcaagttgaaaacaaaaca
tcagaagtcaaacagctgataaaagcaatccaactcacttataatcctgatgaatcatca
aaaccaaatatgatagacgctgctactttgaagtccaggaaaatgttagaagaaattatg
aaatatgaagcatcgattttaacacatgactcaagtattcgatatttgcaggaaatatat
aattcaaataatcaaaagattgttaacctgaaagagaaggtagcccagcttgaagcacag
tgccaggaaccttgcaaagacacggtgcaaatccatgatatcactgggaaagattgtcaa
gacattgccaataagggagctaaacagagcgggctttactttattaaacctctgaaagct
aaccagcaattcttagtctactgtgaaatcgatgggtctggaaatggatggactgtgttt
cagaagagacttgatggcagtgtagatttcaagaaaaactggattcaatataaagaagga
tttggacatctgtctcctactggcacaacagaattttggctgggaaatgagaagattcat
ttgataagcacacagtctgccatcccatatgcattaagagtggaactggaagactggaat
ggcagaaccagtactgcagactatgccatgttcaaggtgggacctgaagctgacaagtac
cgcctaacatatgcctacttcgctggtggggatgctggagatgcctttgatggctttgat
tttggcgatgatcctagtgacaagtttttcacatcccataatggcatgcagttcagtacc
tgggacaatgacaatgataagtttgaaggcaactgtgctgaacaggatggatctggttgg
tggatgaacaagtgtcacgctggccatctcaatggagtttattaccaaggtggcacttac
tcaaaagcatctactcctaatggttatgataatggcattatttgggccacttggaaaacc
cggtggtattccatgaagaaaaccactatgaagataatcccattcaacagactcacaatt
ggagaaggacagcaacaccacctggggggagccaaacaggtcagaccagagcaccctgcg
gaaacagaatatgactcactttaccctgaggatgatttgtag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (5)   
Network (4)   
   KEGG NETWORK (4)   
Disease (5)   
   KEGG DISEASE (2)   
   OMIM (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (32)   
   RefSeq(nuc) (2)   
   GenBank (15)   
   EMBL (15)   
3D Structure (45)   
   PDB (45)   
Protein domain (3)   
   Pfam (3)   
All databases (114)   

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