KEGG   Homo sapiens (human): 22856
Entry
22856             CDS       T01001                                 
Symbol
CHSY1, CHSY, CSS1, ChSy-1, TPBS
Name
(RefSeq) chondroitin sulfate synthase 1
  KO
K13499  chondroitin sulfate synthase [EC:2.4.1.175 2.4.1.226]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00532  Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
hsa01100  Metabolic pathways
Module
hsa_M00058  Glycosaminoglycan biosynthesis, chondroitin sulfate backbone
Network
nt06029  Glycosaminoglycan biosynthesis
  Element
N01580  Chondroitin sulfate biosynthesis
Disease
H01497  Temtamy preaxial brachydactyly syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
    22856 (CHSY1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:hsa01003]
    22856 (CHSY1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.175  glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase
     22856 (CHSY1)
    2.4.1.226  N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase
     22856 (CHSY1)
Glycosyltransferases [BR:hsa01003]
 Glycan extension
  O-Glycan
   22856 (CHSY1)
SSDB
Motif
Pfam: CHGN Fringe Glyco_transf_7C Glyco_tranf_2_2 Galactosyl_T BMFP
Other DBs
NCBI-GeneID: 22856
NCBI-ProteinID: NP_055733
OMIM: 608183
HGNC: 17198
Ensembl: ENSG00000131873
UniProt: Q86X52
Position
15:complement(101175727..101252048)
AA seq 802 aa
MAARGRRAWLSVLLGLVLGFVLASRLVLPRASELKRAGPRRRASPEGCRSGQAAASQAGG
ARGDARGAQLWPPGSDPDGGPRDRNFLFVGVMTAQKYLQTRAVAAYRTWSKTIPGKVQFF
SSEGSDTSVPIPVVPLRGVDDSYPPQKKSFMMLKYMHDHYLDKYEWFMRADDDVYIKGDR
LENFLRSLNSSEPLFLGQTGLGTTEEMGKLALEPGENFCMGGPGVIMSREVLRRMVPHIG
KCLREMYTTHEDVEVGRCVRRFAGVQCVWSYEMQQLFYENYEQNKKGYIRDLHNSKIHQA
ITLHPNKNPPYQYRLHSYMLSRKISELRHRTIQLHREIVLMSKYSNTEIHKEDLQLGIPP
SFMRFQPRQREEILEWEFLTGKYLYSAVDGQPPRRGMDSAQREALDDIVMQVMEMINANA
KTRGRIIDFKEIQYGYRRVNPMYGAEYILDLLLLYKKHKGKKMTVPVRRHAYLQQTFSKI
QFVEHEELDAQELAKRINQESGSLSFLSNSLKKLVPFQLPGSKSEHKEPKDKKINILIPL
SGRFDMFVRFMGNFEKTCLIPNQNVKLVVLLFNSDSNPDKAKQVELMRDYRIKYPKADMQ
ILPVSGEFSRALALEVGSSQFNNESLLFFCDVDLVFTTEFLQRCRANTVLGQQIYFPIIF
SQYDPKIVYSGKVPSDNHFAFTQKTGFWRNYGFGITCIYKGDLVRVGGFDVSIQGWGLED
VDLFNKVVQAGLKTFRSQEVGVVHVHHPVFCDPNLDPKQYKMCLGSKASTYGSTQQLAEM
WLEKNDPSYSKSSNNNGSVRTA
NT seq 2409 nt   +upstreamnt  +downstreamnt
atggccgcgcgcggccggcgcgcctggctcagcgtgctgctcgggctcgtcctgggcttc
gtgctggcctcgcggctcgtcctgccccgggcttccgagctgaagcgagcgggcccacgg
cgccgcgccagccccgagggctgccggtccgggcaggcggcggcttcccaggccggcggg
gcgcgcggcgatgcgcgcggggcgcagctctggccgcccggctcggacccagatggcggc
ccgcgcgacaggaactttctcttcgtgggagtcatgaccgcccagaaatacctgcagact
cgggccgtggccgcctacagaacatggtccaagacaattcctgggaaagttcagttcttc
tcaagtgagggttctgacacatctgtaccaattccagtagtgccactacggggtgtggac
gactcctacccgccccagaagaagtccttcatgatgctcaagtacatgcacgaccactac
ttggacaagtatgaatggtttatgagagcagatgatgacgtgtacatcaaaggagaccgt
ctggagaacttcctgaggagtttgaacagcagcgagcccctctttcttgggcagacaggc
ctgggcaccacggaagaaatgggaaaactggccctggagcctggtgagaacttctgcatg
ggggggcctggcgtgatcatgagccgggaggtgcttcggagaatggtgccgcacattggc
aagtgtctccgggagatgtacaccacccatgaggacgtggaggtgggaaggtgtgtccgg
aggtttgcaggggtgcagtgtgtctggtcttatgagatgcagcagcttttttatgagaat
tacgagcagaacaaaaaggggtacattagagatctccataacagtaaaattcaccaagct
atcacattacaccccaacaaaaacccaccctaccagtacaggctccacagctacatgctg
agccgcaagatatccgagctccgccatcgcacaatacagctgcaccgcgaaattgtcctg
atgagcaaatacagcaacacagaaattcataaagaggacctccagctgggaatccctccc
tccttcatgaggtttcagccccgccagcgagaggagattctggaatgggagtttctgact
ggaaaatacttgtattcggcagttgacggccagccccctcgaagaggaatggactccgcc
cagagggaagccttggacgacattgtcatgcaggtcatggagatgatcaatgccaacgcc
aagaccagagggcgcatcattgacttcaaagagatccagtacggctaccgccgggtgaac
cccatgtatggggctgagtacatcctggacctgctgcttctgtacaaaaagcacaaaggg
aagaaaatgacggtccctgtgaggaggcacgcgtatttacagcagactttcagcaaaatc
cagtttgtggagcatgaggagctggatgcacaagagttggccaagagaatcaatcaggaa
tctggatccttgtcctttctctcaaactccctgaagaagctcgtcccctttcagctccct
gggtcgaagagtgagcacaaagaacccaaagataaaaagataaacatactgattcctttg
tctgggcgtttcgacatgtttgtgagatttatgggaaactttgagaagacgtgtcttatc
cccaatcagaacgtcaagctcgtggttctgcttttcaattctgactccaaccctgacaag
gccaaacaagttgaactgatgagagattaccgcattaagtaccctaaagccgacatgcag
attttgcctgtgtctggagagttttcaagagccctggccctggaagtaggatcctcccag
tttaacaatgaatctttgctcttcttctgcgacgtcgacctcgtgtttactacagaattc
cttcagcgatgtcgagcaaatacagttctgggccaacaaatatattttccaatcatcttc
agccagtatgacccaaagattgtttatagtgggaaagttcccagtgacaaccattttgcc
tttactcagaaaactggcttctggagaaactatgggtttggcatcacgtgtatttataag
ggagatcttgtccgagtgggtggctttgatgtttccatccaaggctgggggctggaggat
gtggaccttttcaacaaggttgtccaggcaggtttgaagacgtttaggagccaggaagta
ggagtagtccacgtccaccatcctgtcttttgtgatcccaatcttgaccccaaacagtac
aaaatgtgcttggggtccaaagcatcgacctatgggtccacccagcagctggctgagatg
tggctggaaaaaaatgatccaagttacagtaaaagcagcaataataatggctcagtgagg
acagcctaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (8)   
   KEGG ENZYME (2)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (11)   
   NAGAHAMA-S (1)   
   OC (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (25)   
   RefSeq(nuc) (9)   
   GenBank (8)   
   EMBL (8)   
Protein domain (6)   
   Pfam (6)   
All databases (92)   

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