KEGG   Homo sapiens (human): 22933
Entry
22933             CDS       T01001                                 
Symbol
SIRT2, SIR2, SIR2L, SIR2L2
Name
(RefSeq) sirtuin 2
  KO
K11412  NAD-dependent protein deacetylase sirtuin 2 [EC:2.3.1.286]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00760  Nicotinate and nicotinamide metabolism
hsa01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    22933 (SIRT2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    22933 (SIRT2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.286  protein acetyllysine N-acetyltransferase
     22933 (SIRT2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HDACs (histone deacetylases)
    SIRTs (sirtuins, class III HDACs)
     22933 (SIRT2)
SSDB
Motif
Pfam: SIR2 YdjO
Other DBs
NCBI-GeneID: 22933
NCBI-ProteinID: NP_036369
OMIM: 604480
HGNC: 10886
Ensembl: ENSG00000068903
UniProt: Q8IXJ6
Structure
Position
19:complement(38878555..38899618)
AA seq 389 aa
MAEPDPSHPLETQAGKVQEAQDSDSDSEGGAAGGEADMDFLRNLFSQTLSLGSQKERLLD
ELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFE
ISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQ
EDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLP
ARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMI
MGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQSGAGV
PNPSTSASPKKSPPPAKDEARTTEREKPQ
NT seq 1170 nt   +upstreamnt  +downstreamnt
atggcagagccagacccctctcaccctctggagacccaggcagggaaggtgcaggaggct
caggactcagattcagactctgagggaggagccgctggtggagaagcagacatggacttc
ctgcggaacttattctcccagacgctcagcctgggcagccagaaggagcgtctgctggac
gagctgaccttggaaggggtggcccggtacatgcagagcgaacgctgtcgcagagtcatc
tgtttggtgggagctggaatctccacatccgcaggcatccccgactttcgctctccatcc
accggcctctatgacaacctagagaagtaccatcttccctacccagaggccatctttgag
atcagctatttcaagaaacatccggaacccttcttcgccctcgccaaggaactctatcct
gggcagttcaagccaaccatctgtcactacttcatgcgcctgctgaaggacaaggggcta
ctcctgcgctgctacacgcagaacatagataccctggagcgaatagccgggctggaacag
gaggacttggtggaggcgcacggcaccttctacacatcacactgcgtcagcgccagctgc
cggcacgaatacccgctaagctggatgaaagagaagatcttctctgaggtgacgcccaag
tgtgaagactgtcagagcctggtgaagcctgatatcgtcttttttggtgagagcctccca
gcgcgtttcttctcctgtatgcagtcagacttcctgaaggtggacctcctcctggtcatg
ggtacctccttgcaggtgcagccctttgcctccctcatcagcaaggcacccctctccacc
cctcgcctgctcatcaacaaggagaaagctggccagtcggaccctttcctggggatgatt
atgggcctcggaggaggcatggactttgactccaagaaggcctacagggacgtggcctgg
ctgggtgaatgcgaccagggctgcctggcccttgctgagctccttggatggaagaaggag
ctggaggaccttgtccggagggagcacgccagcatagatgcccagtcgggggcgggggtc
cccaaccccagcacttcagcttcccccaagaagtccccgccacctgccaaggacgaggcc
aggacaacagagagggagaaaccccagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (7)   
   OC (1)   
Protein sequence (14)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (57)   
   RefSeq(nuc) (13)   
   GenBank (22)   
   EMBL (22)   
3D Structure (38)   
   PDB (38)   
Protein domain (2)   
   Pfam (2)   
All databases (156)   

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