KEGG   Homo sapiens (human): 22949
Entry
22949             CDS       T01001                                 
Symbol
PTGR1, DIG-1, LTB4DH, PGR1, ZADH3
Name
(RefSeq) prostaglandin reductase 1
  KO
K13948  prostaglandin reductase 1 [EC:1.3.1.74 1.3.1.48]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00590  Arachidonic acid metabolism
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    22949 (PTGR1)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.48  13,14-dehydro-15-oxoprostaglandin 13-reductase
     22949 (PTGR1)
    1.3.1.74  2-alkenal reductase [NAD(P)+]
     22949 (PTGR1)
SSDB
Motif
Pfam: ADH_N_2 ADH_zinc_N ADH_zinc_N_2 DUF6616
Other DBs
NCBI-GeneID: 22949
NCBI-ProteinID: NP_001139580
OMIM: 601274
HGNC: 18429
Ensembl: ENSG00000106853
UniProt: Q14914
Structure
Position
9:complement(111549722..111599647)
AA seq 329 aa
MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEG
DTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALG
TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA
YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG
AISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEGKIQYKE
YIIEGFENMPAAFMGMLKGDNLGKTIVKA
NT seq 990 nt   +upstreamnt  +downstreamnt
atggttcgtactaagacatggaccctgaagaagcactttgttggctatcctactaatagt
gactttgagttgaagacagctgagctcccacccttaaaaaatggagaggtcctgcttgaa
gctttgttcctcaccgtggatccctacatgagagtggcagccaaaagattgaaggaaggt
gatacaatgatggggcagcaagtggccaaagttgtggaaagtaaaaatgtagccctacca
aaaggaactattgtactggcttctccaggctggacaacgcactccatttctgatgggaaa
gatctggaaaagctgctgacagagtggccagacacaataccactgtctttggctctgggg
acagttggcatgccaggcctgactgcctactttggcctacttgaaatctgtggtgtgaag
ggtggagaaacagtgatggttaatgcagcagctggagctgtgggctcagtcgtggggcag
attgcaaagctcaagggctgcaaagttgttggagcagtagggtctgatgaaaaggttgcc
taccttcaaaagcttggatttgatgtcgtctttaactacaagacggtagagtctttggaa
gaaaccttgaagaaagcgtctcctgatggttatgattgttattttgataatgtaggtgga
gagttttcaaacactgttatcggccagatgaagaaatttggaaggattgccatatgtgga
gccatctctacatataacagaaccggcccacttcccccaggcccacccccagagattgtt
atctatcaggagcttcgcatggaagcttttgtcgtctaccgctggcaaggagatgcccgc
caaaaagctctgaaggacttgctgaaatgggtcttagagggtaaaatccagtacaaggaa
tatatcattgaaggatttgaaaacatgccagctgcatttatgggaatgctgaaaggagat
aatttggggaagacaatagtgaaagcatga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (8)   
   KEGG ENZYME (2)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (21)   
   OC (1)   
Protein sequence (14)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (28)   
   RefSeq(nuc) (12)   
   GenBank (8)   
   EMBL (8)   
3D Structure (2)   
   PDB (2)   
Protein domain (4)   
   Pfam (4)   
All databases (101)   

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