KEGG   Homo sapiens (human): 22974
Entry
22974             CDS       T01001                                 
Symbol
TPX2, C20orf1, C20orf2, DIL-2, DIL2, FLS353, GD:C20orf1, HCA519, HCTP4, REPP86, p100
Name
(RefSeq) TPX2 microtubule nucleation factor
  KO
K16812  targeting protein for Xklp2
Organism
hsa  Homo sapiens (human)
Network
nt06515  Regulation of kinetochore-microtubule interactions
  Element
N01544  Microtubule nucleation
N01549  Branching microtubule nucleation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    22974 (TPX2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Spindle formation proteins
    22974 (TPX2)
  Sister chromatid separation proteins
   Aurora kinases
    Regulators of Aurora kinases
     22974 (TPX2)
SSDB
Motif
Pfam: TPX2_importin Aurora-A_bind TPX2
Other DBs
NCBI-GeneID: 22974
NCBI-ProteinID: NP_036244
OMIM: 605917
HGNC: 1249
Ensembl: ENSG00000088325
UniProt: Q9ULW0 Q643R0
Structure
Position
20:31739290..31801800
AA seq 747 aa
MSQVKSSYSYDAPSDFINFSSLDDEGDTQNIDSWFEEKANLENKLLGKNGTGGLFQGKTP
LRKANLQQAIVTPLKPVDNTYYKEAEKENLVEQSIPSNACSSLEVEAAISRKTPAQPQRR
SLRLSAQKDLEQKEKHHVKMKAKRCATPVIIDEILPSKKMKVSNNKKKPEEEGSAHQDTA
EKNASSPEKAKGRHTVPCMPPAKQKFLKSTEEQELEKSMKMQQEVVEMRKKNEEFKKLAL
AGIGQPVKKSVSQVTKSVDFHFRTDERIKQHPKNQEEYKEVNFTSELRKHPSSPARVTKG
CTIVKPFNLSQGKKRTFDETVSTYVPLAQQVEDFHKRTPNRYHLRSKKDDINLLPSKSSV
TKICRDPQTPVLQTKHRARAVTCKSTAELEAEELEKLQQYKFKARELDPRILEGGPILPK
KPPVKPPTEPIGFDLEIEKRIQERESKKKTEDEHFEFHSRPCPTKILEDVVGVPEKKVLP
ITVPKSPAFALKNRIRMPTKEDEEEDEPVVIKAQPVPHYGVPFKPQIPEARTVEICPFSF
DSRDKERQLQKEKKIKELQKGEVPKFKALPLPHFDTINLPEKKVKNVTQIEPFCLETDRR
GALKAQTWKHQLEEELRQQKEAACFKARPNTVISQEPFVPKKEKKSVAEGLSGSLVQEPF
QLATEKRAKERQELEKRMAEVEAQKAQQLEEARLQEEEQKKEELARLRRELVHKANPIRK
YQGLEIKSSDQPLTVPVSPKFSTRFHC
NT seq 2244 nt   +upstreamnt  +downstreamnt
atgtcacaagttaaaagctcttattcctatgatgccccctcggatttcatcaatttttca
tccttggatgatgaaggagatactcaaaacatagattcatggtttgaggagaaggccaat
ttggagaataagttactggggaagaatggaactggagggctttttcagggcaaaactcct
ttgagaaaggctaatcttcagcaagctattgtcacacctttgaaaccagttgacaacact
tactacaaagaggcagaaaaagaaaatcttgtggaacaatccattccgtcaaatgcttgt
tcttccctggaagttgaggcagccatatcaagaaaaactccagcccagcctcagagaaga
tctcttaggctttctgctcagaaggatttggaacagaaagaaaagcatcatgtaaaaatg
aaagccaagagatgtgccactcctgtaatcatcgatgaaattctaccctctaagaaaatg
aaagtttctaacaacaaaaagaagccagaggaagaaggcagtgctcatcaagatactgct
gaaaagaatgcatcttccccagagaaagccaagggtagacatactgtgccttgtatgcca
cctgcaaagcagaagtttctaaaaagtactgaggagcaagagctggagaagagtatgaaa
atgcagcaagaggtggtggagatgcggaaaaagaatgaagaattcaagaaacttgctctg
gctggaatagggcaacctgtgaagaaatcagtgagccaggtcaccaaatcagttgacttc
cacttccgcacagatgagcgaatcaaacaacatcctaagaaccaggaggaatataaggaa
gtgaactttacatctgaactacgaaagcatccttcatctcctgcccgagtgactaaggga
tgtaccattgttaagcctttcaacctgtcccaaggaaagaaaagaacatttgatgaaaca
gtttctacatatgtgccccttgcacagcaagttgaagacttccataaacgaacccctaac
agatatcatttgaggagcaagaaggatgatattaacctgttaccctccaaatcttctgtg
accaagatttgcagagacccacagactcctgtactgcaaaccaaacaccgtgcacgggct
gtgacctgcaaaagtacagcagagctggaggctgaggagctcgagaaattgcaacaatac
aaattcaaagcacgtgaacttgatcccagaatacttgaaggtgggcccatcttgcccaag
aaaccacctgtgaaaccacccaccgagcctattggctttgatttggaaattgagaaaaga
atccaggagcgagaatcaaagaagaaaacagaggatgaacactttgaatttcattccaga
ccttgccctactaagattttggaagatgttgtgggtgttcctgaaaagaaggtacttcca
atcaccgtccccaagtcaccagcctttgcattgaagaacagaattcgaatgcccaccaaa
gaagatgaggaagaggacgaaccggtagtgataaaagctcaacctgtgccacattatggg
gtgccttttaagccccaaatcccagaggcaagaactgtggaaatatgccctttctcgttt
gattctcgagacaaagaacgtcagttacagaaggagaagaaaataaaagaactgcagaaa
ggggaggtgcccaagttcaaggcacttcccttgcctcattttgacaccattaacctgcca
gagaagaaggtaaagaatgtgacccagattgaacctttctgcttggagactgacagaaga
ggtgctctgaaggcacagacttggaagcaccagctggaagaagaactgagacagcagaaa
gaagcagcttgtttcaaggctcgtccaaacaccgtcatctctcaggagccctttgttccc
aagaaagagaagaaatcagttgctgagggcctttctggttctctagttcaggaacctttt
cagctggctactgagaagagagccaaagagcggcaggagctggagaagagaatggctgag
gtagaagcccagaaagcccagcagttggaggaggccagactacaggaggaagagcagaaa
aaagaggagctggccaggctacggagagaactggtgcataaggcaaatccaatacgcaag
taccagggtctggagataaagtcaagtgaccagcctctgactgtgcctgtatctcccaaa
ttctccactcgattccactgctaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Network (3)   
   KEGG NETWORK (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (11)   
   OC (1)   
Protein sequence (14)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (45)   
   RefSeq(nuc) (11)   
   GenBank (17)   
   EMBL (17)   
3D Structure (13)   
   PDB (13)   
Protein domain (3)   
   Pfam (3)   
All databases (108)   

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