KEGG   Homo sapiens (human): 22983
Entry
22983             CDS       T01001                                 
Symbol
MAST1, MCCCHCM, SAST
Name
(RefSeq) microtubule associated serine/threonine kinase 1
  KO
K08789  MAST-subfamily protein kinase [EC:2.7.11.37]
Organism
hsa  Homo sapiens (human)
Disease
H02519  Mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    22983 (MAST1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.37  MAST-subfamily protein kinase
     22983 (MAST1)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: AGC group
  MAST family [OT]
   22983 (MAST1)
SSDB
Motif
Pfam: DUF1908 Pkinase PK_Tyr_Ser-Thr PDZ_6 PDZ PDZ_2 ABC1 Kinase-like APH Tricorn_PDZ Haspin_kinase Kdo
Other DBs
NCBI-GeneID: 22983
NCBI-ProteinID: NP_055790
OMIM: 612256
HGNC: 19034
Ensembl: ENSG00000105613
UniProt: Q9Y2H9
Structure
Position
19:12838515..12874952
AA seq 1570 aa
MSDSLWTALSNFSMPSFPGGSMFRRTKSCRTSNRKSLILTSTSPTLPRPHSPLPGHLGSS
PLDSPRNFSPNTPAHFSFASSRRADGRRWSLASLPSSGYGTNTPSSTVSSSCSSQERLHQ
LPYQPTVDELHFLSKHFGSTESITDEDGGRRSPAVRPRSRSLSPGRSPSSYDNEIVMMNH
VYKERFPKATAQMEEKLRDFTRAYEPDSVLPLADGVLSFIHHQIIELARDCLTKSRDGLI
TTVYFYELQENLEKLLQDAYERSESLEVAFVTQLVKKLLIIISRPARLLECLEFNPEEFY
HLLEAAEGHAKEGHLVKTDIPRYIIRQLGLTRDPFPDVVHLEEQDSGGSNTPEQDDLSEG
RSSKAKKPPGENDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAF
VERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAE
TVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAR
EFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVI
SDDILWPEGDEALPTEAQLLISSLLQTNPLVRLGAGGAFEVKQHSFFRDLDWTGLLRQKA
EFIPHLESEDDTSYFDTRSDRYHHVNSYDEDDTTEEEPVEIRQFSSCSPRFSKVYSSMEQ
LSQHEPKTPVAAAGSSKREPSTKGPEEKVAGKREGLGGLTLREKTWRGGSPEIKRFSASE
ASFLEGEASPPLGARRRFSALLEPSRFSAPQEDEDEARLRRPPRPSSDPAGSLDARAPKE
ETQGEGTSSAGDSEATDRPRPGDLCPPSKDGDASGPRATNDLVLRRARHQQMSGDVAVEK
RPSRTGGKVIKSASATALSVMIPAVDPHGSSPLASPMSPRSLSSNPSSRDSSPSRDYSPA
VSGLRSPITIQRSGKKYGFTLRAIRVYMGDTDVYSVHHIVWHVEEGGPAQEAGLCAGDLI
THVNGEPVHGMVHPEVVELILKSGNKVAVTTTPFENTSIRIGPARRSSYKAKMARRNKRP
SAKEGQESKKRSSLFRKITKQSNLLHTSRSLSSLNRSLSSSDSLPGSPTHGLPARSPTHS
YRSTPDSAYLGASSQSSSPASSTPNSPASSASHHIRPSTLHGLSPKLHRQYRSARCKSAG
NIPLSPLAHTPSPTQASPPPLPGHTVGSSHTTQSFPAKLHSSPPVVRPRPKSAEPPRSPL
LKRVQSAEKLGASLSADKKGALRKHSLEVGHPDFRKDFHGELALHSLAESDGETPPVEGL
GAPRQVAVRRLGRQESPLSLGADPLLPEGASRPPVSSKEKESPGGAEACTPPRATTPGGR
TLERDVGCTRHQSVQTEDGTGGMARAVAKAALSPVQEHETGRRSSSGEAGTPLVPIVVEP
ARPGAKAVVPQPLGADSKGLQEPAPLAPSVPEAPRGRERWVLEVVEERTTLSGPRSKPAS
PKLSPEPQTPSLAPAKCSAPSSAVTPVPPASLLGSGTKPQVGLTSRCPAEAVPPAGLTKK
GVSSPAPPGP
NT seq 4713 nt   +upstreamnt  +downstreamnt
atgtctgactctctctggaccgcgctttctaatttctcgatgccctccttccccggcggc
agtatgttccgccgcaccaagagctgccgcaccagtaatcggaaaagcctcatcctgacc
agcacttcacccacgctaccgagaccccactccccgctgccaggtcacctaggcagcagt
cccctggacagcccccgaaacttctcccccaacacccccgcccacttctcgtttgcctcc
tcccgaagggcggacggacgccggtggtctctggcctcgctcccttcatctggctatggc
accaacacgcccagttccaccgtctcgtcctcctgctcctcccaggagcgccttcaccag
ctgccctaccagcccacggtggacgagctccacttcctctccaaacacttcgggagcacc
gagagcatcacagacgaggatggtggccgtcgctccccagccgtgcggccccgctcacgg
agcctcagccccgggcgctccccctcctcctacgacaacgagatcgtgatgatgaatcac
gtctacaaggagaggttcccgaaggccactgcgcagatggaggagaagctgcgcgacttt
acccgcgcctacgaacccgacagcgttctgcctctggccgatggcgtgctcagcttcatc
caccaccagatcatcgagctggcccgggactgcctgaccaagtcccgtgacggcctcatc
accacggtctacttctatgaattgcaggagaacctggagaagctccttcaagacgcctat
gaacgctctgagagcttggaggtggccttcgttactcagctggtgaagaagttgcttatt
atcatctcacgccctgcgaggctgctggagtgcctggaattcaaccccgaggagttctac
cacctgctggaggcggccgaaggacacgccaaggagggccaccttgtgaagacggacatc
ccccgctacatcatccgccagctgggcctcacccgtgacccctttccagatgtggtgcat
ctggaggaacaggacagtggtggttccaacacccctgagcaagacgatctctctgagggc
cgcagcagcaaggccaagaaaccgccgggggagaatgacttcgataccatcaagctcata
agcaacggtgcctacggcgctgtctacctggtgcggcaccgcgacacgcggcagcgcttt
gccatgaaaaagatcaacaagcagaacttgatcctccgcaaccagatccagcaggccttt
gtggagcgcgatatcctcaccttcgccgagaacccgtttgtggtcggcatgttctgctcc
tttgagactcggcgccacctctgcatggtcatggaatatgtggaaggcggcgactgtgcc
accctgctgaagaatattggagcgctgcccgtagagatggcccgcatgtactttgctgag
acggtgctagccctggagtatttgcacaactatggcatcgtgcaccgcgacctcaagcct
gacaacctccttatcacctccatgggtcacatcaagctcacagatttcggcctctccaag
atggggctcatgagcctcaccaccaacttatatgaaggccacatcgagaaggacgcccga
gagttcctggacaaacaggtgtgtgggaccccagagtacatcgcgcccgaggtcatcctg
cgtcaaggctacggcaagccagtggactggtgggctatggggatcatcctctacgagttc
ctggtgggctgtgtgcccttcttcggagacacaccagaggagctatttggacaggtcatc
agtgatgacatcctgtggcccgagggggatgaggccctacctacggaggcccaactcctc
atatccagcctcctgcagaccaaccctctggtcaggcttggggcaggcggcgcttttgag
gtgaagcagcacagtttctttcgagacctggactggacagggctgctgaggcagaaggcc
gagttcatcccccacctagagtcggaagatgacactagctactttgacacccgctcagac
aggtatcaccacgtgaactcctatgacgaggatgacacgacggaggaggagcccgtggaa
atccgccagttctcttcctgctctccgcgcttcagcaaggtgtatagcagcatggagcag
ctgtcgcagcacgagcccaagaccccagtagcagctgcagggagcagcaagcgggagccg
agcaccaagggccccgaggagaaggtggccggcaagcgggaggggctgggcggcctgacc
ctgcgtgagaagacctggagagggggctctccggagatcaagcgattctccgcgtccgag
gccagtttcctggagggagaggccagtccccctttgggcgcccgccgccgtttctcggcg
ctgctggagcccagccgcttcagcgccccccaagaggacgaggatgaggcccggctgcgc
aggcctccccggcccagctccgaccccgcgggatccctggatgcacgggcccccaaagag
gagactcaaggggaaggcacctccagcgccggggactccgaggccactgaccgtccacgc
ccaggtgacctctgcccaccctcgaaggatggggatgcatcaggcccaagggctaccaat
gacttggttctgcgccgggcgcggcaccagcagatgtcaggggatgtggcagtagagaag
aggccttctcgaactgggggcaaagtcatcaaatcagcctcagccactgccttatctgtc
atgattcctgcagtggacccacatggaagttcaccccttgctagtcccatgtctccacga
tctctgtcctccaacccatcctcacgggactcctcacccagccgggactactcaccagct
gtcagtgggctccgctcccccatcaccatccagcgctcgggcaagaagtatggcttcaca
ctgcgtgccatccgtgtctacatgggtgacacggatgtctatagtgtccaccacattgtc
tggcatgtggaggaaggaggcccagcccaggaggcaggactctgtgctggggacctcatc
acccacgtgaatggggagcctgtgcatggcatggtgcatcctgaggtcgtggagctgatc
cttaagagtggcaacaaggtagcagtgaccacaacgcccttcgaaaatacctctatccgc
attggtcccgcaaggcgcagcagctacaaggctaaaatggctcggaggaacaagcgaccc
tccgccaaggagggccaggagagcaagaagcgcagctccctcttccggaagatcacgaag
cagtcgaacctgctgcatactagccgctcgctgtcgtcgctgaaccgctcgctgtcatcc
agcgatagtctcccgggctcgcctacgcacgggctgccggcgcgctcgcccacgcacagc
taccgctccacgcctgactccgcctacctaggcgcctcatcccagagcagctccccagcc
tcgagcacgcccaactcgcctgcgtcgtcggcgtcgcaccacattcggcccagcacgctg
cacggactgtcgccaaagctccatcgccagtaccgctctgcgcgatgcaagtcggccggc
aacatccctctatcgccgctggcacacacgccgtcccccacgcaggcgtcaccgccgcca
ctgccgggccacacggtgggcagctcgcacactactcagagcttcccggccaaactgcac
tcatcgcctcccgtcgtgcgcccgcgccccaagagtgccgagccccctcgctcgccgctc
ctcaagcgcgtgcagtcggccgagaagctgggagcctctttgagtgcggacaagaagggc
gcgctgcgcaaacacagcctcgaggtgggccacccggatttccgcaaggacttccatggc
gagctggcgctgcatagccttgccgagtccgacggtgagacgcccccagtcgagggcctt
ggcgcgccccggcaggtcgccgtccgccgcctgggccgacaggagtcacctttgagcctg
ggcgcggacccgttgctgcccgagggtgcctccaggccaccagtgtcgagcaaggagaag
gaatccccggggggcgccgaggcgtgcaccccaccccgcgcgacgacccccggtggccgg
accctggagcgggacgtcggctgcacgcggcatcagagcgtgcagacggaggatggcact
ggcgggatggccagggctgtggccaaggcggcgctgagcccggtgcaggaacacgagaca
ggccggcgcagcagctctggcgaggcgggcacacccctggtacccattgtcgtagagcct
gcgcggcccggggctaaggctgtggtgcctcagcctctgggcgcggactccaaggggttg
caggaacccgcacccctggcgccttccgtgcccgaggccccccggggccgggagcgctgg
gtgttggaggtggtggaggagcgcaccacgctgagcggtcctcgctccaagcccgcctcc
ccaaagctctccccggagccccagacaccctccctagccccagcgaagtgcagtgcaccc
agcagtgcagtgaccccagtcccacccgcatccctcttgggctcaggcaccaagcctcaa
gtggggctgacctcccggtgccctgctgaagctgtgcccccagcaggcctgaccaaaaaa
ggagtgtccagtcccgcacccccgggaccatag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (39)   
   KEGG ORTHOLOGY (1)   
   RefGene (31)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (15)   
   RefSeq(nuc) (1)   
   GenBank (7)   
   EMBL (7)   
3D Structure (2)   
   PDB (2)   
Protein domain (12)   
   Pfam (12)   
All databases (79)   

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