KEGG   Homo sapiens (human): 22986
Entry
22986             CDS       T01001                                 
Symbol
SORCS3, SORCS
Name
(RefSeq) sortilin related VPS10 domain containing receptor 3
  KO
K27083  VPS10 domain-containing receptor SorCS3
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    22986 (SORCS3)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Others
   Others
    22986 (SORCS3)
 Endosome - Lysosome transport
    22986 (SORCS3)
 Endosome - Golgi transport
    22986 (SORCS3)
SSDB
Motif
Pfam: Sortilin-Vps10 Sortilin_C PKD PKD_4
Other DBs
NCBI-GeneID: 22986
NCBI-ProteinID: NP_055793
OMIM: 606285
HGNC: 16699
Ensembl: ENSG00000156395
UniProt: Q9UPU3 Q86XB2
Position
10:104641290..105265242
AA seq 1222 aa
MEAARTERPAGRPGAPLVRTGLLLLSTWVLAGAEITWDATGGPGRPAAPASRPPALSPLS
PRAVASQWPEELASARRAAVLGRRAGPELLPQQGGGRGGEMQVEAGGTSPAGERRGRGIP
APAKLGGARRSRRAQPPITQERGDAWATAPADGSRGSRPLAKGSREEVKAPRAGGSAAED
LRLPSTSFALTGDSAHNQAMVHWSGHNSSVILILTKLYDFNLGSVTESSLWRSTDYGTTY
EKLNDKVGLKTVLSYLYVNPTNKRKIMLLSDPEMESSILISSDEGATYQKYRLTFYIQSL
LFHPKQEDWVLAYSLDQKLYSSMDFGRRWQLMHERITPNRFYWSVAGLDKEADLVHMEVR
TTDGYAHYLTCRIQECAETTRSGPFARSIDISSLVVQDEYIFIQVTTSGRASYYVSYRRE
AFAQIKLPKYSLPKDMHIISTDENQVFAAVQEWNQNDTYNLYISDTRGIYFTLAMENIKS
SRGLMGNIIIELYEVAGIKGIFLANKKVDDQVKTYITYNKGRDWRLLQAPDVDLRGSPVH
CLLPFCSLHLHLQLSENPYSSGRISSKETAPGLVVATGNIGPELSYTDIGVFISSDGGNT
WRQIFDEEYNVWFLDWGGALVAMKHTPLPVRHLWVSFDEGHSWDKYGFTSVPLFVDGALV
EAGMETHIMTVFGHFSLRSEWQLVKVDYKSIFSRHCTKEDYQTWHLLNQGEPCVMGERKI
FKKRKPGAQCALGRDHSGSVVSEPCVCANWDFECDYGYERHGESQCVPAFWYNPASPSKD
CSLGQSYLNSTGYRRIVSNNCTDGLREKYTAKAQMCPGKAPRGLHVVTTDGRLVAEQGHN
ATFIILMEEGDLQRTNIQLDFGDGIAVSYANFSPIEDGIKHVYKSAGIFQVTAYAENNLG
SDTAVLFLHVVCPVEHVHLRVPFVAIRNKEVNISAVVWPSQLGTLTYFWWFGNSTKPLIT
LDSSISFTFLAEGTDTITVQVAAGNALIQDTKEIAVHEYFQSQLLSFSPNLDYHNPDIPE
WRKDIGNVIKRALVKVTSVPEDQILIAVFPGLPTSAELFILPPKNLTERRKGNEGDLEQI
VETLFNALNQNLVQFELKPGVQVIVYVTQLTLAPLVDSSAGHSSSAMLMLLSVVFVGLAV
FLIYKFKRKIPWINIYAQVQHDKEQEMIGSVSQSENAPKITLSDFTEPEELLDKELDTRV
IGGIATIANSESTKEIPNCTSV
NT seq 3669 nt   +upstreamnt  +downstreamnt
atggaggcggcgcgcacggagcgccccgcaggcaggccgggggcgccgcttgtccggacg
gggctcctactcttgtcgacgtgggtcctggccggcgccgagatcacttgggacgcgaca
ggcggtcccggacgcccggcggccccggcttcgcggccaccggcgttgtctccactctcg
ccgcgggcagtggccagccagtggccggaggagctggcgtcggcgcggagagccgccgtg
ctggggcgccgggccggaccagagctgctgccccagcagggcggcggcagaggcggtgag
atgcaggtggaagccggagggacatcaccggcaggcgagcggcggggccggggcatccca
gctcctgccaagcttggcggcgcgaggaggagtcgccgggcgcagcccccaatcacccag
gaacgcggggacgcctgggccactgctccggccgatggttccagaggaagccgtcccctt
gctaagggttcccgggaggaggtgaaggcgccgcgggctggggggtcggcggctgaagac
ctccggctgcccagcacctccttcgcgctgaccggggactcggcccacaaccaagccatg
gtgcactggtcgggacacaacagcagcgtcatacttatcctgacgaagctgtatgacttc
aacctgggcagcgtgactgagagttcactatggaggtcgacagattatggcaccacctat
gaaaagctgaatgacaaagtgggtttgaagactgtcctcagttacctctatgtcaatcca
accaacaaaaggaagattatgcttctcagtgatcctgagatggagagcagcatattgatc
agctcagacgaaggggcgacctatcagaagtatcggctcaccttctatatccagagcctg
ctctttcatcccaagcaagaggactgggtgctggcctacagtttggatcaaaagctctac
agctccatggactttggaagacggtggcaactcatgcatgaacgcatcacacccaacagg
ttttattggtcggtggccggattggataaggaggcggacctggtgcacatggaggtgcgg
accacggatggatatgctcactacctcacctgcaggatccaggaatgtgccgagacaact
agaagtgggccttttgcccgctccattgacatcagttccctggttgtccaggatgaatat
atcttcattcaggtaacaactagtggaagagccagctactacgtgtcttatcgaagagag
gcctttgctcagataaagctgcctaagtactcgttgccaaaggacatgcacatcatcagt
acagacgagaaccaagtatttgctgcggtccaagaatggaaccagaacgacacgtacaac
ctctacatctcagacacgcgtgggatttacttcactctggccatggagaacatcaagagc
agcagaggtctaatggggaacatcattattgaattgtatgaggtagcaggtatcaaaggg
atatttctggcaaacaagaaggtggacgaccaggtgaagacatacatcacttacaacaaa
ggcagggattggcgcctgctgcaagctccggatgtggacctgagaggaagcccagtgcac
tgcctgctgcccttctgttccttacatctgcacctgcaactctctgaaaatccatattcc
tcaggaagaatctctagcaaggagacagccccaggacttgtggtggctacaggcaacatt
ggcccggagctctcatatactgatattggtgtgttcatctcctccgatgggggcaacaca
tggagacagatctttgatgaagagtacaatgtctggttcctagactggggtggtgccctc
gtggccatgaaacacacacctctgccagtcaggcatttgtgggtgagttttgatgagggc
cactcttgggacaagtatggtttcacttcggttcctctctttgttgacggggctctggtg
gaggcaggaatggagacccacatcatgacagtttttggccacttcagcctccgctccgaa
tggcaattggtgaaagtggactacaaatctatcttcagccggcattgcaccaaggaggac
tatcagacctggcacctgctcaatcagggagagccttgtgtcatgggagaaaggaaaata
ttcaagaaacgtaagccaggagctcagtgtgccctgggccgagaccactcaggatcagtg
gtctcagaaccctgtgtctgtgccaattgggacttcgagtgtgactatgggtatgagaga
catggggagagccagtgtgtcccagctttctggtacaatccagcatccccatcaaaggac
tgcagccttggtcaaagctaccttaacagcactgggtatcggcggattgtgtccaacaac
tgcacagatgggctaagggagaagtacaccgccaaggcccagatgtgccctggaaaagcc
cctcggggcctccatgtggtgacgaccgatgggcggctggtggcagagcaggggcacaat
gcaactttcatcatcctcatggaggagggtgatctacaaaggacaaacatccagcttgac
tttggggatgggattgctgtgtcctacgcaaacttcagccccatcgaggacggcatcaag
cacgtgtataagagtgcggggatcttccaggtgacagcctatgcagagaacaaccttggc
tcagacacagctgtcctcttcctgcatgtggtttgtcctgtggagcatgttcatctccga
gttccatttgttgccataagaaataaggaggtcaacatcagtgcagtcgtgtggcccagt
caactggggacccttacctatttctggtggttcggcaatagcacaaagcctctcatcact
ttggacagcagcatttccttcacattccttgcagaaggaaccgacaccatcacagtccag
gtggctgctgggaatgccctcatccaggacacaaaagagattgcagttcatgaatatttc
cagtcccagcttttatcattctctcctaatctggattaccacaatcctgacattcctgag
tggagaaaagatattggcaatgtcatcaagcgagctctggttaaagtaaccagtgtccca
gaggaccagatcctcattgccgtgtttcctggtctccccacttcagcagagcttttcatt
cttccacccaagaacctgacagagaggaggaaaggcaatgaaggggacctggaacaaatt
gtagaaacactgtttaatgctctcaaccaaaatttggtccagtttgagctgaagccgggg
gtacaagtcattgtgtatgtcacacagctgacgttagctccattggtggactccagtgct
gggcacagcagctcagccatgcttatgctattatcagtggtatttgttggcctggctgtg
tttttgatctacaagtttaaaaggaaaatcccttggattaacatctatgctcaagtccaa
cacgacaaggagcaggagatgattgggtcagtgagccaaagtgaaaacgcccccaaaatc
acactcagtgactttacggagcctgaggagctgctggacaaagagctggacacgcgggtc
ataggaggcattgccactattgcaaacagcgaaagcacaaaggagatccccaactgcact
agtgtttaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (11)   
   RefSeq(nuc) (3)   
   GenBank (4)   
   EMBL (4)   
Protein domain (4)   
   Pfam (4)   
All databases (43)   

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