KEGG   Homo sapiens (human): 23031
Entry
23031             CDS       T01001                                 
Symbol
MAST3, DEE108
Name
(RefSeq) microtubule associated serine/threonine kinase 3
  KO
K08789  MAST-subfamily protein kinase [EC:2.7.11.37]
Organism
hsa  Homo sapiens (human)
Disease
H00606  Early infantile epileptic encephalopathy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    23031 (MAST3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.37  MAST-subfamily protein kinase
     23031 (MAST3)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: AGC group
  MAST family [OT]
   23031 (MAST3)
SSDB
Motif
Pfam: DUF1908 Pkinase PK_Tyr_Ser-Thr PDZ_6 PDZ PDZ_2 ABC1 Kinase-like APH Tricorn_PDZ ACTL7A_N Haspin_kinase
Other DBs
NCBI-GeneID: 23031
NCBI-ProteinID: NP_055831
OMIM: 612258
HGNC: 19036
Ensembl: ENSG00000099308
UniProt: O60307
Structure
Position
19:18097778..18151687
AA seq 1309 aa
MDESSLLRRRGLQKELSLPRRGRGCRSGNRKSLVVGTPSPTLSRPLSPLSVPTAGSSPLD
SPRNFSAASALNFPFARRADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRERLHQLPFQP
TPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVMMNHVYRERF
PKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARDCLAKSGENLVTSRYFL
EMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPEEFYHLLEAA
EGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPPAPESPESRALVGQSRR
KPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILT
FAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEY
LHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFIDKQV
CGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWP
EGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLRHKAEFVPQLE
AEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEFLAVQPTP
TFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQSSSSQPERGPSPSLLNT
ISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSLSADTAALSH
ARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGGSGGGSGGRVPKSASVS
ALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIHSSGKKY
GFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLGLVHMDVV
ELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDRRKSLFKKIS
KQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPADTTASPPSA
SPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPSPLACPPISAPPPR
SPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGPEAELVVMRRLHLSERR
DSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALGPTGRD
NT seq 3930 nt   +upstreamnt  +downstreamnt
atggacgagtcgagcctcctgcggcgccgcgggctccagaaggagctgagcctgccacgc
cgaggacgtggctgccgcagcgggaaccgcaagagcttggtggtaggaacgccctccccg
accctctcccggcccctgtcgccattgtcggtcccaacggcaggcagcagccccttggat
agtcctcggaatttctcggctgcctctgccctaaatttcccctttgcccggagggcagac
ggcagaagatggtccctcgcgtctctcccatcttccggctatggaaccaacacacccagc
tccaccctctcgtcaagctcatcctcccgggaacgtctccaccagcttcccttccagccg
acgccggacgagctgcacttcctgtccaagcacttccgcagctcagagaatgtgcttgat
gaggaaggcggccggtcaccccgcctccgaccccgctctcgcagtctcagcccgggccgt
gcaacggggaccttcgacaatgagattgtcatgatgaatcacgtgtaccgggagaggttc
cccaaggccacagcacagatggagggccgtctgcaggagttcctgacggcctacgcgccc
ggcgcccggctggcgctggctgatggcgtcttgggcttcatccaccaccagatcgtcgag
ctggcccgagactgcttggccaagtctggcgagaacctcgtcacctcccgctacttccta
gagatgcaggagaagctggagcggcttctgcaggatgcccatgagcgttcggacagtgag
gaggtcagcttcatcgtccagcttgtccggaaactgctgatcatcatctcacggccagct
cggctgctggagtgtctggagtttgaccctgaggaattttaccacctgctggaggcggct
gagggccatgcgcgggagggccaaggcattaagactgaccttccacagtacatcattggg
cagctgggcctggccaaggaccccctggaggagatggtgccactgagtcacctcgaagaa
gaacagcccccagcacctgagtccccagagagccgcgccctggtcggccagtcacggagg
aagccatgcgaaagcgactttgagaccatcaaactcattagcaacggagcctatggggcc
gtctacctggtgcggcaccgtgacacacggcagcgctttgccatcaagaagatcaacaaa
cagaacttgatcctgcgtaaccagatccagcaggtctttgtggagcgtgacattctcacc
tttgccgagaacccctttgtggtcagcatgttctgctcctttgagacccggcgccaccta
tgtatggtcatggaatacgtggaaggcggcgactgcgccacgctcctgaagaacatgggc
ccgctgcccgtggacatggcccgcctgtacttcgccgagacggtgttggcgctggagtac
ctgcataactatggcatcgtgcaccgtgacctcaaaccagacaatctgctcatcacctcg
cttggccacatcaagctcacggacttcggcctgtccaagatcggcctcatgagcatggcc
accaacctctatgagggccacatcgagaaggacgcccgagagttcatcgacaagcaggtg
tgtgggacgccggagtacatagcccccgaggtgatcttccgccagggctatgggaagcca
gtggactggtgggccatgggcgtcgtcctctatgagtttctggtgggctgcgtgcctttc
tttggagatacccccgaggaactcttcggtcaggtggtcagcgatgagatcatgtggcca
gagggagatgaggcccttccagcagacgcccaggacctcatcaccaggttgctccggcag
agcccgctggaccgtctgggcactggtggcacccacgaagtgaagcagcacccctttttc
ctggccctggactgggcagggcttctccgacacaaagccgagttcgtgccccagctcgaa
gctgaggatgataccagctactttgacacacgttcggaacgttaccgccatctgggctcc
gaggacgacgagaccaatgatgaagaatcgtccacagagatcccccagttctcctcctgc
tcccaccggttcagcaaggtctacagcagctctgagttcctggccgtccagcccactcct
accttcgctgaaaggagcttcagtgaagaccgggaggaggggtgggagcgcagcgaagtg
gactatggccgccggctgagtgctgacatccggctgaggtcctggacatcctctggatcc
tcctgtcagtcatcttcgtcccagcccgagcggggtcccagcccatctctcctgaatacc
atcagcctggacacaatgcccaagtttgccttctcatcagaggatgagggggtaggccca
ggccctgcaggccccaagaggcccgtcttcattctaggggagcctgaccccccaccagcg
gccaccccagtgatgcccaagccctcgagcctttctgccgacacagctgctctcagccac
gcccgcctacggagcaatagcatcggcgcccgacactccacaccaaggcctctggatgcc
ggccggggccgccgccttgggggcccaagagacccagcccctgagaagtccagagcctcc
tccagcggtggcagtggtggcggcagtgggggccgcgtgcccaagtcagcctctgtctct
gccctgtccctcatcatcacggcagatgatggcagcggcggccccctcatgagccccctt
tccccgcgctctctgtcctcgaacccgtcgtcccgtgactcttcgccgagccgagacccg
tcccccgtgtgtggcagcctgcggccccccatcgttatccacagctctggcaagaagtac
ggcttcagcctgcgggcgatccgcgtctacatgggtgatagcgacgtctacactgtgcac
cacgtcgtctggagtgtggaggacggaagccccgcccaggaggcgggcctgcgggctggg
gacctcatcacccacatcaacggggagtcagtgctggggctggtgcacatggacgtcgtg
gagctgctgctgaagagcggcaacaagatatccctgcggaccacagccctggagaacacc
tccatcaaggtgggccccgcccggaagaatgtggccaagggccgcatggcacgcaggagc
aagaggagccgtcggcgggagacccaggatcggcggaagtcacttttcaagaagatctcc
aagcagacctccgtgctgcacaccagccgcagcttctcctccggactccaccactcactg
tcatccagtgagagcctccccggctcgcccacccacagcctctcccccagccccaccact
ccctgccgaagcccagcccctgatgtcccagcagataccactgcatccccacccagcgca
tccccgagctccagcagccccgcctccccagctgctgctggccacacccgccccagctcc
ctgcacggcctggctgccaagcttgggccaccccgccccaagactggccgccgcaagtcc
accagcagcatcccgccctccccgctggcctgcccgcccatctccgcgcccccaccccgc
tcgccctcgcccctgcccgggcacccgcccgcacctgcccgatccccgcggctgcgccgg
ggccagtcagctgacaagctgggcacaggggagcggctggatggggaggcggggcggcgc
actcgtgggccagaggccgagctcgtggtcatgcggcggctgcacctgtccgagcgccga
gactccttcaagaagcaggaggccgtgcaggaggttagcttcgatgagccgcaggaggag
gccactgggctgcccacctcagtgccacagatcgccgtggagggcgaggaagccgtgcca
gtagctctcgggcccaccggaagagactga

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Ontology (3)   
   KEGG BRITE (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (39)   
   KEGG ORTHOLOGY (1)   
   RefGene (33)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (61)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (59)   
DNA sequence (69)   
   RefSeq(nuc) (59)   
   GenBank (5)   
   EMBL (5)   
3D Structure (2)   
   PDB (2)   
Protein domain (12)   
   Pfam (12)   
All databases (191)   

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