KEGG   Homo sapiens (human): 23063
Entry
23063             CDS       T01001                                 
Symbol
WAPL, FOE, KIAA0261, WAPAL
Name
(RefSeq) WAPL cohesin release factor
  KO
K25163  wings apart-like protein
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
Network
nt06512  Chromosome cohesion and segregation
  Element
N01484  Establishment of cohesion
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    23063 (WAPL)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    23063 (WAPL)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Meiosis-specific proteins
   Cohesin complex and associated proteins
    23063 (WAPL)
SSDB
Motif
Pfam: WAPL
Other DBs
NCBI-GeneID: 23063
NCBI-ProteinID: NP_055860
OMIM: 610754
HGNC: 23293
Ensembl: ENSG00000062650
UniProt: Q7Z5K2 A8K273 B2RTX8
Structure
Position
10:complement(86435256..86521792)
AA seq 1190 aa
MTSRFGKTYSRKGGNGSSKFDEVFSNKRTTLSTKWGETTFMAKLGQKRPNFKPDIQEIPK
KPKVEEESTGDPFGFDSDDESLPVSSKNLAQVKCSSYSESSEAAQLEEVTSVLEANSKIS
HVVVEDTVVSDKCFPLEDTLLGKEKSTNRIVEDDASISSCNKLITSDKVENFHEEHEKNS
HHIHKNADDSTKKPNAETTVASEIKETNDTWNSQFGKRPESPSEISPIKGSVRTGLFEWD
NDFEDIRSEDCILSLDSDPLLEMKDDDFKNRLENLNEAIEEDIVQSVLRPTNCRTYCRAN
KTKSSQGASNFDKLMDGTSQALAKANSESSKDGLNQAKKGGVSCGTSFRGTVGRTRDYTV
LHPSCLSVCNVTIQDTMERSMDEFTASTPADLGEAGRLRKKADIATSKTTTRFRPSNTKS
KKDVKLEFFGFEDHETGGDEGGSGSSNYKIKYFGFDDLSESEDDEDDDCQVERKTSKKRT
KTAPSPSLQPPPESNDNSQDSQSGTNNAENLDFTEDLPGVPESVKKPINKQGDKSKENTR
KIFSGPKRSPTKAVYNARHWNHPDSEELPGPPVVKPQSVTVRLSSKEPNQKDDGVFKAPA
PPSKVIKTVTIPTQPYQDIVTALKCRREDKELYTVVQHVKHFNDVVEFGENQEFTDDIEY
LLSGLKSTQPLNTRCLSVISLATKCAMPSFRMHLRAHGMVAMVFKTLDDSQHHQNLSLCT
AALMYILSRDRLNMDLDRASLDLMIRLLELEQDASSAKLLNEKDMNKIKEKIRRLCETVH
NKHLDLENITTGHLAMETLLSLTSKRAGDWFKEELRLLGGLDHIVDKVKECVDHLSRDED
EEKLVASLWGAERCLRVLESVTVHNPENQSYLIAYKDSQLIVSSAKALQHCEELIQQYNR
AEDSICLADSKPLPHQNVTNHVGKAVEDCMRAIIGVLLNLTNDNEWGSTKTGEQDGLIGT
ALNCVLQVPKYLPQEQRFDIRVLGLGLLINLVEYSARNRHCLVNMETSCSFDSSICSGEG
DDSLRIGGQVHAVQALVQLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQ
WVSTEKTDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINV
TTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQKSISRVIEYLEHC
NT seq 3573 nt   +upstreamnt  +downstreamnt
atgacatccagatttgggaaaacatacagtaggaaaggtggaaatggcagttcaaaattc
gatgaagtcttttccaacaaacggactacccttagcacaaaatggggagagaccacattt
atggctaaattagggcagaagaggcccaatttcaaaccagatatccaagaaattccgaag
aaacctaaagtggaagaagaaagtactggagatccttttggatttgatagtgatgatgag
tctctaccagtttcttcaaagaatttagcccaggttaagtgttcctcttattcagaatct
agtgaagctgctcagttggaagaggtcacttcagtacttgaagctaatagcaaaattagt
catgtggtcgttgaagacactgtcgtttctgataaatgcttccctttggaggacacttta
cttgggaaagaaaagagcacaaaccgaattgtagaagatgatgcaagcataagtagctgt
aataaattaataacttcagataaagtggagaattttcatgaagaacatgaaaagaatagt
caccatattcacaaaaatgctgatgacagtactaagaaacccaatgcagaaactacagtg
gcttctgaaatcaaggaaacaaatgatacttggaactcccagtttgggaaaaggccagaa
tcaccatcagaaatatctccaatcaagggatctgttagaactggtttgtttgaatgggat
aatgattttgaagatatcagatcagaagactgtattttaagtttggatagtgatcccctt
ttggagatgaaggatgacgattttaaaaatcgattggaaaatctgaatgaagccattgag
gaagatattgtacaaagtgttcttaggccaaccaactgtaggacgtactgtagggccaat
aaaacgaaatcctcccaaggagcatcaaattttgataagctgatggacggcaccagtcag
gccttagccaaagcaaacagtgaatcgagtaaagatggcctgaatcaggcaaagaaaggg
ggtgtaagttgtgggaccagttttagagggacagttggacggactagagattacactgtt
ttacatccatcttgcttgtcagtttgtaatgttaccatacaggatactatggaacgcagc
atggatgagttcactgcatccactcctgcagatttgggagaagctggtcgtctcagaaaa
aaggcagatattgcaacttctaagactactactagatttcgacctagtaatactaaatcc
aaaaaggatgttaaacttgaattttttggttttgaagatcatgagacaggaggtgatgaa
ggaggttctggaagttctaattacaaaattaagtattttggctttgatgatctcagtgaa
agcgaagatgatgaagatgatgactgtcaagtagaaagaaagacaagcaaaaaaagaact
aaaacagctccatcaccctccttgcagcctcccccagaaagcaatgataattcccaggac
agtcagtctggtactaacaatgcagaaaacttggattttacagaggacttgcctggtgtg
cctgaaagtgtgaagaagcccataaataaacaaggagataaatcaaaggaaaataccaga
aagatttttagtggccccaaacggtcacccacaaaagctgtatataatgccagacattgg
aatcatccagattcagaagaactgcctgggccaccagtagtaaaacctcagagtgtcaca
gtgaggctgtcttcaaaggaaccaaatcaaaaagatgatggagtttttaaggctcctgca
ccaccatccaaagtgataaaaactgtgacaatacctactcagccctaccaagatatagtt
actgcactgaaatgcagacgagaagacaaagaattatatactgttgttcagcacgtgaag
cacttcaacgatgttgtagaatttggtgaaaatcaagagttcactgatgacattgagtac
ttgttaagtggcttaaagagcactcagcctctaaacacacgttgccttagtgttattagc
ttggctactaaatgtgccatgcccagttttcgaatgcacctgagagcacatgggatggta
gcaatggtctttaaaaccttggatgattcccagcaccatcagaatctgtccctctgtaca
gctgccctcatgtatatactgagtagagatcgtttgaacatggatcttgatagagctagc
ttagatctaatgattcgacttttggaactggaacaagatgcttcatcagccaagctactg
aatgaaaaagacatgaacaaaattaaagaaaaaatccgaaggctctgtgaaactgtacac
aacaagcatcttgatctagaaaatataacgactgggcatttagctatggagacattatta
tcccttacttctaaacgagcaggagactggtttaaagaagaactccggcttttgggtggt
ctggatcatattgtagataaagtaaaagaatgtgtggatcatttaagtagagatgaggat
gaagagaaactggtagcctcactatggggagcagagagatgtttacgagttttagaaagt
gtaactgtgcataatcccgaaaatcaaagctacttgatagcatataaagattcccaactt
attgtttcatcagctaaagcattacagcattgtgaagaactgattcagcagtacaaccgt
gctgaggacagcatatgcttagctgacagtaagcctctgcctcaccagaatgtaactaac
catgtaggcaaagcagtggaggactgcatgagggccatcatcggggtgttgcttaattta
actaatgataatgagtggggcagcaccaaaacaggagagcaggacggtctcataggcaca
gcgctgaactgtgtgcttcaggttccaaagtacctacctcaggagcagagatttgatatt
cgagtgctgggcttaggtctgctgataaatctagtggagtatagtgctcggaatcggcac
tgtcttgtcaacatggaaacatcgtgctcttttgattcttccatctgtagtggagaaggg
gatgatagtttaaggataggtggacaagttcatgctgtccaggctttagtgcagctattc
cttgagcgagagcgggcagcccagctagcagaaagtaaaacagatgagttgatcaaagat
gctcccaccactcagcatgataagagtggagagtggcaagaaacaagtggagaaatacag
tgggtgtcaactgaaaagactgatggtacagaagagaaacataagaaggaggaggaggat
gaagaacttgacctcaataaagcccttcagcatgccggcaaacacatggaggattgcatt
gtggcctcctacacagcactacttcttgggtgtctctgccaggaaagtccaatcaatgta
accactgtgcgggaatatctgccagaaggagacttttcaataatgacagagatgctcaaa
aaatttttgagttttatgaatctcacttgtgctgttggaacaactggccagaaatctatc
tctagagtgattgaatatttggaacattgctag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (62)   
   RefSeq(nuc) (2)   
   GenBank (30)   
   EMBL (30)   
3D Structure (2)   
   PDB (2)   
Protein domain (1)   
   Pfam (1)   
All databases (94)   

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