KEGG   Homo sapiens (human): 2313
Entry
2313              CDS       T01001                                 
Symbol
FLI1, BDPLT21, EWSR2, FLI-1, SIC-1
Name
(RefSeq) Fli-1 proto-oncogene, ETS transcription factor
  KO
K09436  friend leukemia integration 1 transcription factor
Organism
hsa  Homo sapiens (human)
Pathway
hsa05202  Transcriptional misregulation in cancer
Network
nt06240  Transcription (cancer)
  Element
N00133  EWSR1-FLI1 fusion to transcriptional activation
N00134  EWSR1-FLI1 fusion to transcriptional repression
Disease
H00035  Ewing sarcoma
H01235  Bleeding disorder platelet-type
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    2313 (FLI1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    2313 (FLI1)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Helix-turn-helix
   Tryptophan clusters Ets-type
    2313 (FLI1)
SSDB
Motif
Pfam: Ets SAM_PNT
Other DBs
NCBI-GeneID: 2313
NCBI-ProteinID: NP_002008
OMIM: 193067
HGNC: 3749
Ensembl: ENSG00000151702
UniProt: Q01543
Structure
Position
11:128685351..128813267
AA seq 452 aa
MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQ
PVRVNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTN
ERRVIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATT
LYNTEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNK
SPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCI
TWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF
DFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAAS
QYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY
NT seq 1359 nt   +upstreamnt  +downstreamnt
atggacgggactattaaggaggctctgtcggtggtgagcgacgaccagtccctctttgac
tcagcgtacggagcggcagcccatctccccaaggccgacatgactgcctcggggagtcct
gactacgggcagccccacaagatcaaccccctcccaccacagcaggagtggatcaatcag
ccagtgagggtcaacgtcaagcgggagtatgaccacatgaatggatccagggagtctccg
gtggactgcagcgttagcaaatgcagcaagctggtgggcggaggcgagtccaaccccatg
aactacaacagctatatggacgagaagaatggcccccctcctcccaacatgaccaccaac
gagaggagagtcatcgtccccgcagaccccacactgtggacacaggagcatgtgaggcaa
tggctggagtgggccataaaggagtacagcttgatggagatcgacacatcctttttccag
aacatggatggcaaggaactgtgtaaaatgaacaaggaggacttcctccgcgccaccacc
ctctacaacacggaagtgctgttgtcacacctcagttacctcagggaaagttcactgctg
gcctataatacaacctcccacaccgaccaatcctcacgattgagtgtcaaagaagaccct
tcttatgactcagtcagaagaggagcttggggcaataacatgaattctggcctcaacaaa
agtcctccccttggaggggcacaaacgatcagtaagaatacagagcaacggccccagcca
gatccgtatcagatcctgggcccgaccagcagtcgcctagccaaccctggaagcgggcag
atccagctgtggcaattcctcctggagctgctctccgacagcgccaacgccagctgtatc
acctgggaggggaccaacggggagttcaaaatgacggaccccgatgaggtggccaggcgc
tggggcgagcggaaaagcaagcccaacatgaattacgacaagctgagccgggccctccgt
tattactatgataaaaacattatgaccaaagtgcacggcaaaagatatgcttacaaattt
gacttccacggcattgcccaggctctgcagccacatccgaccgagtcgtccatgtacaag
tacccttctgacatctcctacatgccttcctaccatgcccaccagcagaaggtgaacttt
gtccctccccatccatcctccatgcctgtcacttcctccagcttctttggagccgcatca
caatactggacctcccccacggggggaatctaccccaaccccaacgtcccccgccatcct
aacacccacgtgccttcacacttaggcagctactactag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (3)   
   KEGG NETWORK (3)   
Disease (4)   
   KEGG DISEASE (2)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (39)   
   RefSeq(nuc) (9)   
   GenBank (15)   
   EMBL (15)   
3D Structure (9)   
   PDB (9)   
Protein domain (2)   
   Pfam (2)   
All databases (87)   

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