KEGG   Homo sapiens (human): 23235
Entry
23235             CDS       T01001                                 
Symbol
SIK2, LOH11CR1I, QIK, SIK-2, SNF1LK2
Name
(RefSeq) salt inducible kinase 2
  KO
K16311  serine/threonine-protein kinase SIK2 [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04922  Glucagon signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    23235 (SIK2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    23235 (SIK2)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    23235 (SIK2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     23235 (SIK2)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CAMK group
  CAMKL family
   23235 (SIK2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    23235 (SIK2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like UBA_BRSK ABC1 Haspin_kinase Kdo DUF5716_C
Other DBs
NCBI-GeneID: 23235
NCBI-ProteinID: NP_056006
OMIM: 608973
HGNC: 21680
Ensembl: ENSG00000170145
UniProt: Q9H0K1
Position
11:111602449..111730855
AA seq 926 aa
MVMADGPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVN
LEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEAR
RKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSP
PYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFM
SEDCEHLIRRMLVLDPSKRLTIAQIKEHKWMLIEVPVQRPVLYPQEQENEPSIGEFNEQV
LRLMHSLGIDQQKTIESLQNKSYNHFAAIYFLLVERLKSHRSSFPVEQRLDGRQRRPSTI
AEQTVAKAQTVGLPVTMHSPNMRLLRSALLPQASNVEAFSFPASGCQAEAAFMEEECVDT
PKVNGCLLDPVPPVLVRKGCQSLPSNMMETSIDEGLETEGEAEEDPAHAFEAFQSTRSGQ
RRHTLSEVTNQLVVMPGAGKIFSMNDSPSLDSVDSEYDMGSVQRDLNFLEDNPSLKDIML
ANQPSPRMTSPFISLRPTNPAMQALSSQKREVHNRSPVSFREGRRASDTSLTQGIVAFRQ
HLQNLARTKGILELNKVQLLYEQIGPEADPNLAPAAPQLQDLASSCPQEEVSQQQESVST
LPASVHPQLSPRQSLETQYLQHRLQKPSLLSKAQNTCQLYCKEPPRSLEQQLQEHRLQQK
RLFLQKQSQLQAYFNQMQIAESSYPQPSQQLPLPRQETPPPSQQAPPFSLTQPLSPVLEP
SSEQMQYSPFLSQYQEMQLQPLPSTSGPRAAPPLPTQLQQQQPPPPPPPPPPRQPGAAPA
PLQFSYQTCELPSAASPAPDYPTPCQYPVDGAQQSDLTGPDCPRSPGLQEAPSSYDPLAL
SELPGLFDCEMLDAVDPQHNGYVLVN
NT seq 2781 nt   +upstreamnt  +downstreamnt
atggtcatggcggatggcccgaggcacttgcagcgcgggccggtccgggtggggttctac
gacatcgagggcacgctgggcaagggcaacttcgctgtggtgaagctggggcggcaccgg
atcaccaagacggaggtggcaataaaaataatcgataagtctcagctggatgcagtgaac
cttgagaaaatctaccgagaagtacaaataatgaaaatgttagaccaccctcacataatc
aaactttatcaggtaatggagaccaaaagtatgttgtaccttgtgacagaatatgccaaa
aatggagaaatttttgactatcttgctaatcatggccggttaaatgagtctgaagccagg
cgaaaattctggcaaatcctgtctgctgttgattattgtcatggtcggaagattgtgcac
cgtgacctcaaagctgaaaatctcctgctggataacaacatgaatatcaaaatagcagat
ttcggttttggaaatttctttaaaagtggtgaactgctggcaacatggtgtggcagcccc
ccttatgcagccccagaagtctttgaagggcagcagtatgaaggaccacagctggacatc
tggagtatgggagttgttctttatgtccttgtctgtggagctctgccctttgatggaccg
actcttccaattttgaggcagagggttctggaaggaagattccggattccgtatttcatg
tcagaagattgcgagcaccttatccgaaggatgttggtcctagacccatccaaacggcta
accatagcccaaatcaaggagcataaatggatgctcatagaagttcctgtccagagacct
gttctctatccacaagagcaagaaaatgagccatccatcggggagtttaatgagcaggtt
ctgcgactgatgcacagccttggaatagatcagcagaaaaccattgagtctttgcagaac
aagagctataaccactttgctgccatttatttcttgttggtggagcgcctgaaatcacat
cggagcagtttcccagtggagcagagacttgatggccgccagcgtcggcctagcaccatt
gctgagcaaacagttgccaaggcacagactgtggggctcccagtgaccatgcattcaccg
aacatgaggctgctgcgatctgccctcctcccccaggcatccaacgtggaggccttttca
tttccagcatctggctgtcaggcggaagctgcattcatggaagaagagtgtgtggacact
ccaaaggtcaatggctgtctgcttgaccctgtgcctcctgtcctggtgcggaagggatgc
cagtcactgcccagcaacatgatggagacctccattgacgaagggctggagacagaagga
gaggccgaggaagaccccgctcatgcctttgaggcatttcagtccacacgcagcgggcag
agacggcacactctgtcagaagtgaccaatcaactggtcgtgatgcctggggcagggaaa
attttctccatgaatgacagcccctcccttgacagtgtggactctgagtatgatatgggg
tctgttcagagggacctgaactttctggaagacaacccttcccttaaggacatcatgtta
gccaatcagccttcaccccgcatgacatctcccttcataagcctgagacctaccaaccca
gccatgcaggctctgagctcccagaaacgagaggtccacaacaggtctccagtgagcttc
agagagggccgcagagcatcagatacctccctcacccagggaattgtagcatttagacaa
catcttcagaatctggctagaaccaaaggaattctagagttgaacaaagtgcagttgttg
tatgaacaaataggaccggaggcagaccctaacctggcgccggcggctcctcagctccag
gaccttgctagcagctgccctcaggaagaagtttctcagcagcaggaaagcgtctccact
ctccctgccagcgtgcatccccagctgtccccacggcagagcctggagacccagtacctg
cagcacagactccagaagcccagccttctgtcaaaggcccagaacacctgtcagctttat
tgcaaagaaccaccgcggagccttgagcagcagctgcaggaacataggctccagcagaag
cgactctttcttcagaagcagtctcaactgcaggcctattttaatcagatgcagatagca
gagagctcctacccacagccaagtcagcagctgccccttccccgccaggagactccaccg
ccttctcagcaggccccaccgttcagcctgacccagcccctgagccccgtcctggagcct
tcctccgagcagatgcaatacagccctttcctcagccagtaccaagagatgcagcttcag
cccctgccctccacttccggtccccgggctgctcctcctctgcccacgcagctacagcag
cagcagccgccaccgccaccaccccctccaccaccacgacagccaggagctgccccagcc
cccttacagttctcctatcagacttgtgagctgccaagcgctgcttcccctgcgccagac
tatcccactccctgtcagtatcctgtggatggagcccagcagagcgacctaacggggcca
gactgtcccagaagcccaggactgcaagaggccccctccagctacgacccactagccctc
tctgagctacctggactctttgattgtgaaatgctagacgctgtggatccacaacacaac
gggtatgtcctggtgaattag

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (35)   
   RefSeq(nuc) (3)   
   GenBank (16)   
   EMBL (16)   
Protein domain (8)   
   Pfam (8)   
All databases (73)   

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