KEGG   Homo sapiens (human): 23339
Entry
23339             CDS       T01001                                 
Symbol
VPS39, TLP, VAM6, hVam6p
Name
(RefSeq) VPS39 subunit of HOPS complex
  KO
K20183  Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
Organism
hsa  Homo sapiens (human)
Pathway
hsa04140  Autophagy - animal
hsa04148  Efferocytosis
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06532  Autophagy
  Element
N01300  Tethering of late endosomes and lysosomes
N01301  Salmonella SifA to Tethering of late endosomes and lysosomes
N01721  Autophagosome and lysosome fusion, tethering factor
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    23339 (VPS39)
   04148 Efferocytosis
    23339 (VPS39)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    23339 (VPS39)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    23339 (VPS39)
Membrane trafficking [BR:hsa04131]
 Endosome - Lysosome transport
  Tethering complex
   Hops complex
    23339 (VPS39)
SSDB
Motif
Pfam: Vps39_2 Vps39_1 CNH Clathrin KCTD11_21_C EcoR124_C
Other DBs
NCBI-GeneID: 23339
NCBI-ProteinID: NP_001288067
OMIM: 612188
HGNC: 20593
Ensembl: ENSG00000166887
UniProt: Q96JC1
Structure
Position
15:complement(42158701..42208304)
AA seq 886 aa
MHDAFEPVPILEKLPLQIDCLAAWEEWLLVGTKQGHLLLYRIRKDVVPADVASPESGSCN
RFEVTLEKSNKNFSKKIQQIHVVSQFKILVSLLENNIYVHDLLTFQQITTVSKAKGASLF
TCDLQHTETGEEVLRMCVAVKKKLQLYFWKDREFHELQGDFSVPDVPKSMAWCENSICVG
FKRDYYLIRVDGKGSIKELFPTGKQLEPLVAPLADGKVAVGQDDLTVVLNEEGICTQKCA
LNWTDIPVAMEHQPPYIIAVLPRYVEIRTFEPRLLVQSIELQRPRFITSGGSNIIYVASN
HFVWRLIPVPMATQIQQLLQDKQFELALQLAEMKDDSDSEKQQQIHHIKNLYAFNLFCQK
RFDESMQVFAKLGTDPTHVMGLYPDLLPTDYRKQLQYPNPLPVLSGAELEKAHLALIDYL
TQKRSQLVKKLNDSDHQSSTSPLMEGTPTIKSKKKLLQIIDTTLLKCYLHTNVALVAPLL
RLENNHCHIEESEHVLKKAHKYSELIILYEKKGLHEKALQVLVDQSKKANSPLKGHERTV
QYLQHLGTENLHLIFSYSVWVLRDFPEDGLKIFTEDLPEVESLPRDRVLGFLIENFKGLA
IPYLEHIIHVWEETGSRFHNCLIQLYCEKVQGLMKEYLLSFPAGKTPVPAGEEEGELGEY
RQKLLMFLEISSYYDPGRLICDFPFDGLLEERALLLGRMGKHEQALFIYVHILKDTRMAE
EYCHKHYDRNKDGNKDVYLSLLRMYLSPPSIHCLGPIKLELLEPKANLQAALQVLELHHS
KLDTTKALNLLPANTQINDIRIFLEKVLEENAQKKRFNQVLKNLLHAEFLRVQEERILHQ
QVKCIITEEKVCMVCKKKIGNSAFARYPNGVVVHYFCSKEVNPADT
NT seq 2661 nt   +upstreamnt  +downstreamnt
atgcacgacgctttcgagccagtgccgatcctagaaaagctgcctctgcaaatcgactgt
ctggctgcctgggaggaatggcttcttgtgggaaccaaacaaggacatcttcttctctat
aggattcggaaggacgttgtgccagcagatgtagcatcacctgaaagcggcagttgcaac
agatttgaagtgacactagagaaatccaataagaacttctccaaaaagattcagcagatc
catgtggtttcccagtttaagattctggtcagcttgttagaaaataacatttatgtccat
gacctattgacatttcaacaaatcactacggtttcaaaggcaaagggagcatcactgttt
acttgtgacctccagcacacagagaccggtgaggaggtgttacggatgtgtgtggcagta
aaaaagaagctgcagctctatttctggaaggacagggaatttcatgaattgcagggggac
tttagtgtgccagatgtgcccaagtccatggcgtggtgtgaaaattctatctgtgtgggt
ttcaagagagactactacctaataagggtggatggaaaggggtccatcaaagagctcttt
ccaacaggaaaacagctggagcccttagttgcacctctggcagatggaaaagtggctgtg
ggccaggatgatctcaccgtggtactcaatgaggaagggatctgcacacagaaatgtgcc
ctgaactggacggacataccagtggccatggagcaccagcctccctacatcattgcagtg
ttgcctcgatatgttgagatccgaacatttgaaccgaggcttctggtccaaagcattgaa
ttgcaaaggccccgtttcattacctcaggaggatcaaacattatctatgtggccagcaat
cattttgtttggagactcatccctgtccccatggcaacccaaatccaacaacttctccag
gacaagcagtttgaattggctctgcagctcgcagaaatgaaagatgattctgacagtgaa
aagcagcaacaaattcatcacatcaagaacttgtatgccttcaacctcttctgccagaag
cgttttgatgagtccatgcaggtctttgctaaacttggcacagatcccacccatgtgatg
ggcctgtaccctgacctgctgcccacagactacagaaagcagttgcagtatcccaaccca
ttgcctgtgctctccggggctgaattggagaaggctcacttagctctgattgactacctg
acacagaaacgaagtcaattggtaaagaagctgaatgactctgatcaccagtcaagcacc
tcaccgctcatggaaggcactcccaccatcaaatccaagaagaagctgctacaaatcatc
gacaccaccctgctcaagtgctatctccatacaaatgtggccctggtggcccccttgcta
cgcctggagaacaatcactgccacatcgaggagagcgagcacgtgctaaagaaggctcac
aagtacagtgagcttatcatcctgtatgagaagaaggggctccacgagaaagctctgcag
gtgctcgtggaccagtccaagaaagccaactcccctctgaaaggccacgagaggacagtg
cagtatctgcagcatctgggcacagaaaacctgcatttgattttctcctactcagtgtgg
gtgctgagagacttcccagaagatggcctgaagatatttactgaagatctcccggaagtg
gagtctctgccacgtgatcgagtcctcggcttcttaatagagaattttaagggtctggct
attccttatctggaacacatcatccatgtttgggaggagacaggctctcggttccacaac
tgcctgatccagctatactgtgagaaggtgcaaggtctgatgaaggagtatctcctgtcc
ttccctgcaggcaaaaccccagtcccagctggagaggaagagggtgagctgggagaatac
cggcaaaagctcctcatgttcttggagatttccagctactatgatccaggccggctcatc
tgtgattttccctttgatggcctcttagaagaacgagctctcctgttggggcgcatgggg
aaacatgaacaagctcttttcatttatgtccacatcttgaaggatacaaggatggctgag
gagtactgccacaaacactatgaccgaaacaaagatggcaacaaagatgtgtatctgtcc
ctgcttcggatgtacctgtcgccccccagcattcactgcctggggccaatcaagctggaa
ctactggagccaaaagccaacctccaggccgctctgcaggtcctcgagctacaccacagc
aaactggacaccaccaaggccctcaaccttctgccagcaaacactcagatcaatgacata
cgcatcttcctggaaaaggtcttggaagaaaatgcacaaaagaaacggttcaatcaagtg
ctcaagaaccttctccatgcagaattcctgagggtccaggaagagcggattttacaccag
caggtgaagtgcatcatcacagaggagaaggtgtgcatggtgtgtaagaagaagattggg
aacagtgcatttgcaagataccccaatggagtggtcgtccattacttctgttccaaagag
gtaaacccagctgacacttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Network (5)   
   KEGG NETWORK (5)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (32)   
   RefSeq(nuc) (8)   
   GenBank (12)   
   EMBL (12)   
3D Structure (1)   
   PDB (1)   
Protein domain (6)   
   Pfam (6)   
All databases (78)   

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