KEGG   Homo sapiens (human): 23370
Entry
23370             CDS       T01001                                 
Symbol
ARHGEF18, P114-RhoGEF, RP78, SA-RhoGEF, p114RhoGEF
Name
(RefSeq) Rho/Rac guanine nucleotide exchange factor 18
  KO
K21066  A-kinase anchor protein 18
Organism
hsa  Homo sapiens (human)
Pathway
hsa04530  Tight junction
Disease
H00527  Retinitis pigmentosa
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    23370 (ARHGEF18)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    23370 (ARHGEF18)
Membrane trafficking [BR:hsa04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    23370 (ARHGEF18)
SSDB
Motif
Pfam: PH_16 RhoGEF PH
Other DBs
NCBI-GeneID: 23370
NCBI-ProteinID: NP_001124427
OMIM: 616432
HGNC: 17090
Ensembl: ENSG00000104880
UniProt: Q6ZSZ5 A0A087WZG4
Position
19:7348937..7479989
AA seq 1119 aa
MGNAHSKSGDRHSALPGRPELSFYGSFPRKWSENVFLDNELLTSKILSVLRPQSERGFRA
GDLRYPTHFLSTNSVLASVTASLKEHPRGTLLSDGSPALSRNVGMTVSQKGGPQPTPSPA
GPGTQLGPITGEMDEADSAFLKFKQTADDSLSLTSPNTESIFVEDPYTASLRSEIESDGH
EFEAESWSLAVDAAYAKKQKREVVKRQDVLYELMQTEVHHVRTLKIMLKVYSRALQEELQ
FSSKAIGRLFPCADDLLETHSHFLARLKERRQESLEEGSDRNYVIQKIGDLLVQQFSGEN
GERMKEKYGVFCSGHNEAVSHYKLLLQQNKKFQNLIKKIGNFSIVRRLGVQECILLVTQR
ITKYPVLVERIIQNTEAGTEDYEDLTQALNLIKDIISQVDAKVSECEKGQRLREIAGKMD
LKSSSKLKNGLTFRKEDMLQRQLHLEGMLCWKTTSGRLKDILAILLTDVLLLLQEKDQKY
VFASVDSKPPVISLQKLIVREVANEEKAMFLISASLQGPEMYEIYTSSKEDRNAWMAHIQ
RAVESCPDEEEGPFSLPEEERKVVEARATRLRDFQERLSMKDQLIAQSLLEKQQIYLEMA
EMGGLEDLPQPRGLFRGGDPSETLQGELILKSAMSEIEGIQSLICRQLGSANGQAEDGGS
STGPPRRAETFAGYDCTNSPTKNGSFKKKVSSTDPRPRDWRGPPNSPDLKLSDSDIPGSS
EESPQVVEAPGTESDPRLPTVLESELVQRIQTLSQLLLNLQAVIAHQDSYVETQRAAIQE
REKQFRLQSTRGNLLLEQERQRNFEKQREERAALEKLQSQLRHEQQRWERERQWQHQELE
RAGARLQEREGEARQLRERLEQERAELERQRQAYQHDLERLREAQRAVERERERLELLRR
LKKQNTAPGALPPDTLAEAQPPSHPPSFNGEGLEGPRVSMLPSGVGPEYAERPEVARRDS
APTENRLAKSDVPIQLLSATNQFQRQAAVQQQIPTKLAASTKGGKDKGGKSRGSQRWESS
ASFDLKQQLLLNKLMGKDESTSRNRRSLSPILPGRHSPAPPPDPGFPAPSPPPADSPSEG
FSLKAGGTALLPGPPAPSPLPATPLSAKEDASKEDVIFF
NT seq 3360 nt   +upstreamnt  +downstreamnt
atggggaatgcgcactccaaaagcggggacaggcacagcgcgctccccggccgccccgag
ctgtctttttacggctctttccccaggaaatggagcgagaacgtcttcttggataacgag
ctgctgacctccaagatcctgtctgtgctgcggccgcagtcggagcggggcttccgcgcc
ggggacctccgctacccgacccactttctcagcaccaactctgtccttgcctctgtcaca
gcctcgctcaaggagcacccccggggcaccctcctgtccgatggcagcccggccctgtcc
aggaatgtcggtatgacggtctctcagaaagggggtccccagccaacaccgagcccggct
ggccctgggacgcaactcggaccaatcacaggagagatggatgaagccgattctgcgttt
ttaaaatttaagcagacagctgatgactctctgtcccttacatctccaaacaccgagtcc
atttttgtagaagatccctacaccgcctcgctgaggagtgagattgagtcagacggccac
gagtttgaagctgagtcctggagcctcgccgtggatgcagcctacgccaagaagcaaaag
agggaggtggtgaaaagacaagatgtcctttatgagctgatgcagacagaggtgcaccac
gtgcggacgctcaagatcatgctgaaggtgtactccagggccctgcaggaggagctgcag
ttcagcagcaaggccattggccgcctcttcccatgcgctgacgacctgctggagacgcac
agccacttcctcgctcggctcaaggagcgccgccaggagtccctggaggagggcagtgac
cggaattatgtcatccagaaaatcggcgacctcctggttcagcagttttcaggtgaaaat
ggggagagaatgaaagaaaagtacggtgtgttttgtagtggccacaatgaagctgttagt
cattacaagttgctgcttcagcaaaacaagaaatttcaaaacttgatcaagaaaattggc
aacttctccatcgtgcggcggcttggcgtgcaggagtgcattctcctggttacacaacgc
ataaccaaatacccagtgctggtggagcgcatcatccagaacacggaagctggcactgag
gactatgaagacctgacccaggccttgaacctcatcaaagatatcatctcacaagtggac
gccaaggtcagtgagtgtgagaagggccagcgcctcagggagatcgcagggaagatggac
ctgaagtcttccagcaaactcaagaacgggctcaccttccgcaaggaagacatgcttcag
cggcagctccacctggagggcatgctatgctggaagaccacatcagggcgcttgaaagat
atcctggctatcctgctgaccgacgtacttttgctgctacaagaaaaagatcagaaatac
gtctttgcttctgtggactcaaagccacccgtcatctcgttacaaaagctcatcgtgagg
gaagtggccaacgaggagaaagcgatgtttctgatcagcgcctccttgcaagggccggag
atgtatgaaatctacacgagctccaaagaggacaggaacgcctggatggcccacatccaa
agggctgtggagagctgccctgacgaggaggaggggcccttcagcctgcccgaagaggaa
aggaaggtggtcgaggcccgcgccacgagactccgggactttcaagagcggttgagcatg
aaagaccagctgatcgcacagagcctcctagagaaacagcagatctacctggagatggcc
gagatgggcggcctcgaagacctgccccagccccgaggcctattccgtggaggggaccca
tccgagaccctgcagggggagctaattctcaagtcggccatgagcgagatcgagggcatc
cagagcctgatctgcaggcagctgggcagcgccaacggccaggcggaagacggaggcagc
tccacaggcccgcccaggagggctgagaccttcgcgggctacgactgcacaaacagcccc
accaagaatggcagtttcaagaagaaagtcagcagcactgaccccaggccccgagactgg
cgaggccccccaaacagcccggacttgaagctcagtgacagtgacattcctgggagctct
gaggaatcgccgcaggtggtggaggcgccaggcacggaatccgatccccgtctgcccacc
gtcctggagtcggagcttgtccagcggatccagacactgtcccagctgctcctgaacctt
caggcggtaatcgcccaccaggacagctatgtggagacgcagcgggctgccatccaggag
cgggagaagcagttccggctgcagtcgacgcgtgggaacctgctgctggagcaggagcgg
caacgcaacttcgagaagcagcgggaggagcgcgcggccctggagaagctgcagagccag
ctgcggcacgagcagcagcgctgggagcgcgagcgccagtggcagcaccaggagctggag
cgtgcgggcgcgcggctgcaggagcgcgagggcgaggcgcggcagctacgcgagcggctg
gagcaggagcgggccgagctggagcgccagcgccaggcctaccagcacgacctggagcgg
ctgcgcgaggcccagcgtgccgtggagcgcgagcgggagcgcctggagctgctgcgccgc
ctcaagaagcagaacaccgcgccaggcgcgctgccgcccgacacactggccgaggcccag
cccccaagccaccctcccagcttcaacggggaagggctggagggccctcgtgtgagcatg
ctgccatccggcgtggggccagagtacgcagagcgccccgaggtggctcgccgggacagc
gcccccaccgagaaccggctggccaagagcgatgtgcccatccagctgctcagcgccacc
aaccagttccagaggcaggcggccgtgcagcagcagatccccaccaagctggcggcctcc
accaagggtggcaaggacaagggcggcaagagcaggggctctcagcgctgggagagctca
gcgtccttcgacctgaagcagcagctgctgctcaacaagctcatggggaaagatgagagc
acctcacggaaccgccgctcgctgagccctatcctgcccggcagacacagtcctgcgccc
ccaccagaccctggcttccccgccccgagcccaccgccagctgacagcccctccgagggc
ttctctctcaaggccgggggcacagccctcctgcccgggcccccagctccctcgccactg
ccggccacaccactcagcgccaaggaggacgccagcaaagaagacgtcatcttcttctaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (33)   
   KEGG ORTHOLOGY (1)   
   RefGene (26)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (27)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (24)   
DNA sequence (52)   
   RefSeq(nuc) (28)   
   GenBank (12)   
   EMBL (12)   
Protein domain (3)   
   Pfam (3)   
All databases (122)   

Download RDF
DBGET integrated database retrieval system