KEGG   Homo sapiens (human): 23450
Entry
23450             CDS       T01001                                 
Symbol
SF3B3, RSE1, SAP130, SF3b130, STAF130
Name
(RefSeq) splicing factor 3b subunit 3
  KO
K12830  splicing factor 3B subunit 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa03040  Spliceosome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    23450 (SF3B3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    23450 (SF3B3)
   03041 Spliceosome [BR:hsa03041]
    23450 (SF3B3)
   03036 Chromosome and associated proteins [BR:hsa03036]
    23450 (SF3B3)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Coactivators
    SAGA/TFTC/STAGA complex
     23450 (SF3B3)
Spliceosome [BR:hsa03041]
 Complex A
  U2 snRNP components
   U2 snRNP specific factors
    23450 (SF3B3)
 Complex B
    23450 (SF3B3)
 Complex C
   U2 SnRNP specific factors
    23450 (SF3B3)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HAT complexes
    STAGA complex
     23450 (SF3B3)
    TFTC complex
     23450 (SF3B3)
SSDB
Motif
Pfam: MMS1_N CPSF_A
Other DBs
NCBI-GeneID: 23450
NCBI-ProteinID: NP_036558
OMIM: 605592
HGNC: 10770
Ensembl: ENSG00000189091
UniProt: Q15393 A8K6V3
Structure
Position
16:70523816..70577668
AA seq 1217 aa
MFLYNLTLQRATGISFAIHGNFSGTKQQEIVVSRGKILELLRPDPNTGKVHTLLTVEVFG
VIRSLMAFRLTGGTKDYIVVGSDSGRIVILEYQPSKNMFEKIHQETFGKSGCRRIVPGQF
LAVDPKGRAVMISAIEKQKLVYILNRDAAARLTISSPLEAHKANTLVYHVVGVDVGFENP
MFACLEMDYEEADNDPTGEAAANTQQTLTFYELDLGLNHVVRKYSEPLEEHGNFLITVPG
GSDGPSGVLICSENYITYKNFGDQPDIRCPIPRRRNDLDDPERGMIFVCSATHKTKSMFF
FLAQTEQGDIFKITLETDEDMVTEIRLKYFDTVPVAAAMCVLKTGFLFVASEFGNHYLYQ
IAHLGDDDEEPEFSSAMPLEEGDTFFFQPRPLKNLVLVDELDSLSPILFCQIADLANEDT
PQLYVACGRGPRSSLRVLRHGLEVSEMAVSELPGNPNAVWTVRRHIEDEFDAYIIVSFVN
ATLVLSIGETVEEVTDSGFLGTTPTLSCSLLGDDALVQVYPDGIRHIRADKRVNEWKTPG
KKTIVKCAVNQRQVVIALTGGELVYFEMDPSGQLNEYTERKEMSADVVCMSLANVPPGEQ
RSRFLAVGLVDNTVRIISLDPSDCLQPLSMQALPAQPESLCIVEMGGTEKQDELGERGSI
GFLYLNIGLQNGVLLRTVLDPVTGDLSDTRTRYLGSRPVKLFRVRMQGQEAVLAMSSRSW
LSYSYQSRFHLTPLSYETLEFASGFASEQCPEGIVAISTNTLRILALEKLGAVFNQVAFP
LQYTPRKFVIHPESNNLIIIETDHNAYTEATKAQRKQQMAEEMVEAAGEDERELAAEMAA
AFLNENLPESIFGAPKAGNGQWASVIRVMNPIQGNTLDLVQLEQNEAAFSVAVCRFSNTG
EDWYVLVGVAKDLILNPRSVAGGFVYTYKLVNNGEKLEFLHKTPVEEVPAAIAPFQGRVL
IGVGKLLRVYDLGKKKLLRKCENKHIANYISGIQTIGHRVIVSDVQESFIWVRYKRNENQ
LIIFADDTYPRWVTTASLLDYDTVAGADKFGNICVVRLPPNTNDEVDEDPTGNKALWDRG
LLNGASQKAEVIMNYHVGETVLSLQKTTLIPGGSESLVYTTLSGGIGILVPFTSHEDHDF
FQHVEMHLRSEHPPLCGRDHLSFRSYYFPVKNVIDGDLCEQFNSMEPNKQKNVSEELDRT
PPEVSKKLEDIRTRYAF
NT seq 3654 nt   +upstreamnt  +downstreamnt
atgtttctgtacaacttaaccttgcagagagccactggcatcagctttgccattcatgga
aacttttctggaaccaaacaacaagaaattgttgtttcccgtgggaagatcttggagctg
cttcgcccagaccccaacactggcaaagtacataccctactcactgtggaagtattcggt
gttatccggtcactcatggcctttaggctgacaggtggcaccaaagactacattgtagtt
ggcagtgactctggtcgaattgttattttggaataccagccatctaagaatatgtttgag
aagattcaccaagaaacctttggcaagagtggatgccgtcgcatcgttcctggccagttc
ttagctgtggatcccaaagggcgagccgttatgattagtgccattgagaaacagaaattg
gtgtatattttgaacagagatgctgcagcccgacttaccatttcatctcccctggaagcc
cacaaagcaaacactttagtgtatcatgtagttggagtagatgtcggatttgaaaatcca
atgtttgcttgtctggaaatggattatgaggaagcagacaatgatccaacaggggaagca
gcagctaatacccagcagacacttactttctatgagctagaccttggtttaaatcatgtg
gtccgaaaatacagtgaacctttggaggaacacggcaacttccttattacagttccagga
gggtcagatggtccaagtggagtactgatctgctctgaaaactatattacttacaagaac
tttggtgaccagccagatatccgctgtccaattcccaggaggcggaatgacctggatgac
cctgaaagaggaatgatttttgtctgctctgcaacccataaaaccaaatcgatgttcttc
tttttggctcaaactgagcagggagatatctttaagatcactttggagacagatgaagat
atggttactgagatccggctcaaatattttgatactgtacccgttgctgctgccatgtgt
gtgcttaaaacagggttcctttttgtagcatcagaatttggaaaccattacttatatcaa
attgcacatcttggagatgatgatgaagaacctgagttttcatcagccatgcctctggaa
gaaggagacacattcttttttcagccaagaccacttaaaaaccttgtgctggttgatgag
ttggacagcctctctcccattctgttttgccagatagctgatctggccaatgaagatact
ccacagttgtatgtggcctgtggtaggggaccccgatcatctctgagagtcctaagacat
ggacttgaggtgtcagaaatggctgtttctgagctacctggtaaccccaacgctgtctgg
acagtgcgtcgacacattgaagatgagtttgatgcctacatcattgtgtctttcgtgaat
gccaccctagtgttgtccattggagaaactgtagaagaagtgactgactctgggttcctg
gggaccaccccgaccttgtcctgctccttattaggagatgatgccttggtgcaggtctat
ccagatggcattcggcacatacgagcagacaagagagtcaatgagtggaagacccctgga
aagaaaacaattgtgaagtgtgcagtgaaccagcgacaagtggtgattgccctgacagga
ggagagctggtctatttcgagatggatccttcaggacagctgaatgagtacacagaacgg
aaggagatgtcagcagatgtggtgtgcatgagtctggccaatgtaccccctggagagcag
cggtctcgcttcctggctgtggggcttgtggacaacactgtcagaatcatctccctggat
ccctcagactgtttgcaacctctaagcatgcaggctctcccagcccagcctgagtccttg
tgtatcgtggaaatgggtgggactgagaagcaggatgagctgggtgagaggggctcgatt
ggcttcctatacctgaatattgggctacagaacggtgtgctgctgaggactgtcttggac
cctgtcactggggatttgtctgatactcgcactcggtacctggggtcccgtcctgtgaag
ctcttccgagtccgaatgcaaggccaggaggcagtattggccatgtcaagccgctcatgg
ttgagctattcttaccaatctcgcttccatctcaccccactgtcttacgagacactggaa
tttgcatcgggttttgcctcggaacagtgtcccgagggcattgtggccatctccaccaac
accctacggattttggcattagagaagctcggtgctgtcttcaatcaagtagccttccca
ctgcagtacacacccaggaaatttgtcatccaccctgagagtaacaaccttattatcatt
gaaacggaccacaatgcctacactgaggccacgaaagctcagagaaagcagcagatggca
gaggaaatggtggaagcagcaggggaggatgagcgggagctggccgcagagatggcagca
gcattcctcaatgaaaacctccctgaatccatctttggagctcccaaggctggcaatggg
cagtgggcctctgtgatccgagtgatgaatcccattcaagggaacacactggaccttgtc
cagctggaacagaatgaggcagcttttagtgtggctgtgtgcaggttttccaacactggt
gaagactggtatgtgctggtgggtgtggccaaggacctgatactaaacccccgatctgtg
gcagggggcttcgtctatacttacaagcttgtgaacaatggggaaaaactggagtttttg
cacaagactcctgtggaagaggtccctgctgctattgccccattccaggggagggtgttg
attggtgtggggaagctgttgcgtgtctatgacctgggaaagaagaagttactccgaaaa
tgtgagaataagcatattgccaattatatctctgggatccagactatcggacatagggta
attgtatctgatgtccaagaaagtttcatctgggttcgctacaagcgtaatgaaaaccag
cttatcatctttgctgatgatacctacccccgatgggtcactacagccagcctcctggac
tatgacactgtggctggggcagacaagtttggcaacatatgtgtggtgaggctcccacct
aacaccaatgatgaagtagatgaggatcctacaggaaacaaagccctgtgggaccgtggc
ttgctcaatggggcctcccagaaggcagaggtgatcatgaactaccatgtcggggagacg
gtgctgtccttgcagaagaccacgctgatccctggaggctcagaatcacttgtctatacc
accttgtctggaggaattggcatccttgtgccattcacgtcccatgaggaccatgacttc
ttccagcatgtggaaatgcacctgcggtctgaacatccccctctctgtgggcgggaccac
ctcagctttcgctcctactacttccctgtgaagaatgtgattgatggagacctctgtgag
cagttcaattccatggaacccaacaaacaaaagaacgtctctgaagaactggaccgaacc
ccacccgaagtgtccaagaaactcgaggatatccggacccgctacgccttctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (35)   
   KEGG ORTHOLOGY (1)   
   RefGene (26)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (29)   
   RefSeq(nuc) (1)   
   GenBank (14)   
   EMBL (14)   
3D Structure (36)   
   PDB (36)   
Protein domain (2)   
   Pfam (2)   
All databases (113)   

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