KEGG   Homo sapiens (human): 23463
Entry
23463             CDS       T01001                                 
Symbol
ICMT, HSTE14, MST098, MSTP098, PCCMT, PCMT, PPMT
Name
(RefSeq) isoprenylcysteine carboxyl methyltransferase
  KO
K00587  protein-S-isoprenylcysteine O-methyltransferase [EC:2.1.1.100]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00900  Terpenoid backbone biosynthesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    23463 (ICMT)
Enzymes [BR:hsa01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.100  protein-S-isoprenylcysteine O-methyltransferase
     23463 (ICMT)
SSDB
Motif
Pfam: ICMT PEMT DUF1295
Other DBs
NCBI-GeneID: 23463
NCBI-ProteinID: NP_036537
OMIM: 605851
HGNC: 5350
Ensembl: ENSG00000116237
UniProt: O60725
Position
1:complement(6221193..6235964)
AA seq 284 aa
MAGCAARAPPGSEARLSLATFLLGASVLALPLLTRAGLQGRTGLALYVAGLNALLLLLYR
PPRYQIAIRACFLGFVFGCGTLLSFSQSSWSHFGWYMCSLSLFHYSEYLVTAVNNPKSLS
LDSFLLNHSLEYTVAALSSWLEFTLENIFWPELKQITWLSVTGLLMVVFGECLRKAAMFT
AGSNFNHVVQNEKSDTHTLVTSGVYAWFRHPSYVGWFYWSIGTQVMLCNPICGVSYALTV
WRFFRDRTEEEEISLIHFFGEEYLEYKKRVPTGLPFIKGVKVDL
NT seq 855 nt   +upstreamnt  +downstreamnt
atggcgggctgcgcggcgcgggctccgccgggctctgaggcgcgtctcagcctcgccacc
ttcctgctgggcgcctcggtgctcgcgctgccgctgctcacgcgcgccggcctgcagggc
cgcaccgggctggcgctctacgtggccgggctcaacgcgctgctgctgctgctctatcgg
ccgcctcgctaccagatagccatccgagcttgtttcctggggtttgtgttcggctgcggc
acgctgctaagttttagccagtcttcttggagtcactttggctggtacatgtgctccctg
tcattgttccactattctgaatacttggtgacagcagtcaataatcccaaaagtctgtcc
ttggattcctttctcctgaatcacagcctggagtatacagtagctgctctttcttcttgg
ttagagttcacacttgaaaatatcttttggccagaactgaagcagattacctggctcagt
gtcacagggctgctgatggtggtcttcggagaatgtctgaggaaggcggccatgtttaca
gctggctccaatttcaaccacgtggtacagaatgaaaaatcagatacacatactctggtg
accagtggagtgtacgcttggtttcggcatccttcttacgtcgggtggttttactggagt
attggaactcaggtgatgctgtgtaaccccatctgcggcgtcagctatgccctgacagtg
tggcgattcttccgcgatcgaacagaagaagaagaaatctcactaattcacttttttgga
gaggagtacctggagtataagaagagggtgcccacgggcctgcctttcataaagggggtc
aaggtggacctgtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (8)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (28)   
   RefSeq(nuc) (6)   
   GenBank (11)   
   EMBL (11)   
Protein domain (3)   
   Pfam (3)   
All databases (66)   

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