KEGG   Homo sapiens (human): 23483
Entry
23483             CDS       T01001                                 
Symbol
TGDS, CATMANS, SDR2E1, TDPGD
Name
(RefSeq) TDP-glucose 4,6-dehydratase
  KO
K01710  dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
Organism
hsa  Homo sapiens (human)
Pathway
hsa01100  Metabolic pathways
hsa01250  Biosynthesis of nucleotide sugars
Disease
H01845  Catel-Manzke syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    23483 (TGDS)
   01055 Biosynthesis of vancomycin group antibiotics
    23483 (TGDS)
Enzymes [BR:hsa01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.46  dTDP-glucose 4,6-dehydratase
     23483 (TGDS)
SSDB
Motif
Pfam: GDP_Man_Dehyd Epimerase Polysacc_synt_2 3Beta_HSD RmlD_sub_bind NAD_binding_4 NAD_binding_10 adh_short Methyltransf_31
Other DBs
NCBI-GeneID: 23483
NCBI-ProteinID: NP_055120
OMIM: 616146
HGNC: 20324
Ensembl: ENSG00000088451
UniProt: O95455
Position
13:complement(94574054..94596273)
AA seq 350 aa
MSAACWEEPWGLPGGFAKRVLVTGGAGFIASHMIVSLVEDYPNYMIINLDKLDYCASLKN
LETISNKQNYKFIQGDICDSHFVKLLFETEKIDIVLHFAAQTHVDLSFVRAFEFTYVNVY
GTHVLVSAAHEARVEKFIYVSTDEVYGGSLDKEFDESSPKQPTNPYASSKAAAECFVQSY
WEQYKFPVVITRSSNVYGPHQYPEKVIPKFISLLQHNRKCCIHGSGLQTRNFLYATDVVE
AFLTVLKKGKPGEIYNIGTNFEMSVVQLAKELIQLIKETNSESEMENWVDYVNDRPTNDM
RYPMKSEKIHGLGWRPKVPWKEGIKKTIEWYRENFHNWKNVEKALEPFPV
NT seq 1053 nt   +upstreamnt  +downstreamnt
atgtcggcggcgtgttgggaggaaccgtggggtcttcccggcggctttgcgaagcgggtc
ctggtgaccggcggtgctggtttcattgcatcacatatgattgtctctttagtggaagat
tatccaaactatatgatcataaatctagacaagctggattactgtgcaagcttgaagaat
cttgaaaccatttctaacaaacagaactacaaatttatacagggtgacatatgtgattct
cactttgtgaaactgctttttgaaacagagaaaatagatatagtactacattttgccgca
caaacacatgtagatctttcattcgtacgtgcctttgagtttacctatgttaatgtttat
ggcactcacgttttggtaagtgctgctcatgaagccagagtggagaagtttatttatgtc
agcacagatgaagtatatggtggcagtcttgataaggaatttgatgaatcttcacccaaa
caacctacaaatccttatgcatcatctaaagcagctgctgaatgttttgtacagtcttac
tgggaacaatataagtttccagttgtcatcacaagaagcagtaatgtttatggaccacat
caatatccagaaaaggttattccaaaatttatatctttgctacagcacaacaggaaatgt
tgcattcatgggtcagggcttcaaacaagaaacttcctttatgctactgatgttgtagaa
gcatttctcactgtcctcaaaaaagggaaaccaggtgaaatttataacatcggaaccaat
tttgaaatgtcagttgtccagcttgccaaagaactaatacaactgatcaaagagaccaat
tcagagtctgaaatggaaaattgggttgattatgttaatgatagacccaccaatgacatg
agatacccaatgaagtcagaaaaaatacatggcttaggatggagacctaaagtgccttgg
aaagaaggaataaagaaaacaattgaatggtacagagagaattttcacaactggaagaat
gtggaaaaggcattagaaccctttccggtataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (30)   
   RefSeq(nuc) (8)   
   GenBank (11)   
   EMBL (11)   
Protein domain (9)   
   Pfam (9)   
All databases (69)   

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