KEGG   Homo sapiens (human): 23498
Entry
23498             CDS       T01001                                 
Symbol
HAAO, 3-HAO, HAO, VCRL1, h3HAO
Name
(RefSeq) 3-hydroxyanthranilate 3,4-dioxygenase
  KO
K00452  3-hydroxyanthranilate 3,4-dioxygenase [EC:1.13.11.6]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00380  Tryptophan metabolism
hsa01100  Metabolic pathways
hsa01240  Biosynthesis of cofactors
Module
hsa_M00038  Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate
hsa_M00912  NAD biosynthesis, tryptophan => quinolinate => NAD
Network
nt06036  Lysine degradation
  Element
N01723  NAD biosynthesis
Disease
H02087  Vertebral, cardiac, renal, and limb defects syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    23498 (HAAO)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.6  3-hydroxyanthranilate 3,4-dioxygenase
     23498 (HAAO)
SSDB
Motif
Pfam: 3-HAO Cupin_2 AraC_binding Cupin_1 JmjC_2
Other DBs
NCBI-GeneID: 23498
NCBI-ProteinID: NP_036337
OMIM: 604521
HGNC: 4796
Ensembl: ENSG00000162882
UniProt: P46952
Structure
Position
2:complement(42767089..42792583)
AA seq 286 aa
MERRLGVRAWVKENRGSFQPPVCNKLMHQEQLKVMFIGGPNTRKDYHIEEGEEVFYQLEG
DMVLRVLEQGKHRDVVIRQGEIFLLPARVPHSPQRFANTVGLVVERRRLETELDGLRYYV
GDTMDVLFEKWFYCKDLGTQLAPIIQEFFSSEQYRTGKPIPDQLLKEPPFPLSTRSIMEP
MSLDAWLDSHHRELQAGTPLSLFGDTYETQVIAYGQGSSEGLRQNVDVWLWQLEGSSVVT
MGGRRLSLAPDDSLLVLAGTSYAWERTQGSVALSVTQDPACKKPLG
NT seq 861 nt   +upstreamnt  +downstreamnt
atggagcgccgcctgggagtgagggcctgggtgaaggagaaccggggctccttccagccc
ccggtctgcaacaagctcatgcaccaggagcagctcaaagtcatgttcatcggaggcccc
aacaccaggaaggactatcacatcgaagagggtgaagaggtattttaccagctggaggga
gacatggttctccgagtcctggagcaagggaaacaccgggatgtggtcattcggcaggga
gagatattcctcctgcctgccagggtgccccactcaccacagaggtttgccaacaccgtg
gggctggtggttgagcgaaggcggctggagaccgagctagatgggctcaggtactatgtg
ggcgacaccatggacgttctgtttgagaagtggttctactgcaaggacctcggcacgcag
ttggcccccatcatccaggagttcttcagctctgagcagtacagaacaggaaagcccatc
cctgaccagctgctcaaggagccaccattccctctgagcacacgatccatcatggagccc
atgtccctggatgcctggctggacagccaccacagggagctgcaggcaggcacaccactc
agcctgtttggggacacctatgagacccaggtgatcgcctatgggcaaggcagcagcgaa
ggcctgagacagaatgtggacgtgtggctgtggcagctggagggctcctcggtggtgaca
atggggggacggcgcctgagcctggcccctgatgacagcctcctggtgctagctgggacc
tcgtatgcctgggagcgaacacaaggctctgtggccctgtctgtgacccaggaccctgcc
tgcaagaagcccctggggtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (19)   
   RefSeq(nuc) (5)   
   GenBank (7)   
   EMBL (7)   
3D Structure (3)   
   PDB (3)   
Protein domain (5)   
   Pfam (5)   
All databases (70)   

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