KEGG   Homo sapiens (human): 23678
Entry
23678             CDS       T01001                                 
Symbol
SGK3, CISK, SGK2, SGKL
Name
(RefSeq) serum/glucocorticoid regulated kinase family member 3
  KO
K13304  serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04068  FoxO signaling pathway
hsa04151  PI3K-Akt signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    23678 (SGK3)
   04151 PI3K-Akt signaling pathway
    23678 (SGK3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    23678 (SGK3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     23678 (SGK3)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: AGC group
  SGK family [OT]
   23678 (SGK3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PX Pkinase_C Kinase-like ABC1 Kdo
Other DBs
NCBI-GeneID: 23678
NCBI-ProteinID: NP_001028750
OMIM: 607591
HGNC: 10812
Ensembl: ENSG00000104205
UniProt: Q96BR1 Q5H9Q5
Structure
Position
8:66712781..66862022
AA seq 496 aa
MQRDHTMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNT
LKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMD
SPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAK
RKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVL
DFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHV
VLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPP
FYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFE
SLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASVLEADD
AFVGFSYAPPSEDLFL
NT seq 1491 nt   +upstreamnt  +downstreamnt
atgcaaagagatcacaccatggactacaaggaaagctgcccaagtgtaagcattcccagc
tccgatgaacacagagagaaaaagaagaggtttactgtttataaagttctggtttcagtg
ggaagaagtgaatggtttgtcttcaggagatatgcagagtttgataaactttataacact
ttaaaaaaacagtttcctgctatggccctgaagattcctgccaagagaatatttggtgat
aattttgatccagattttattaaacaaagacgagcaggactaaacgaattcattcagaac
ctagttaggtatccagaactttataaccatccagatgtcagagcattccttcaaatggac
agtccaaaacaccagtcagatccatctgaagatgaggatgaaagaagttctcagaagcta
cactctacctcacagaacatcaacctgggaccgtctggaaatcctcatgccaaaccaact
gactttgatttcttaaaagttattggaaaaggcagctttggcaaggttcttcttgcaaaa
cggaaactggatggaaaattttatgctgtcaaagtgttacagaaaaaaatagttctcaac
agaaaagagcaaaaacatattatggctgaacgtaatgtgctcttgaaaaatgtgaaacat
ccgtttttggttggattgcattattccttccaaacaactgaaaagctttattttgttctg
gattttgttaatggaggggagctttttttccacttacaaagagaacggtcctttcctgag
cacagagctaggttttacgctgctgaaattgctagtgcattgggttacttacattccatc
aaaatagtatacagagacttgaaaccagaaaatattcttttggattcagtaggacatgtt
gtcttaacagattttgggctttgtaaagaaggaattgctatttctgacaccactaccaca
ttttgtgggacaccagagtatcttgcacctgaagtaattagaaaacagccctatgacaat
actgtagattggtggtgccttggggctgttctgtatgaaatgctgtatggattgcctcct
ttttattgccgagatgttgctgaaatgtatgacaatatccttcacaaacccctaagtttg
aggccaggagtgagtcttacagcctggtccattctggaagaactcctagaaaaagacagg
caaaatcgacttggtgccaaggaagactttcttgaaattcagaatcatcctttttttgaa
tcactcagctgggctgaccttgtacaaaagaagattccaccaccatttaatcctaatgtg
gctggaccagatgatatcagaaactttgacacagcatttacagaagaaacagttccatat
tctgtgtgtgtatcttctgactattctatagtgaatgccagtgtattggaggcagatgat
gcattcgttggtttctcttatgcacctccttcagaagacttatttttgtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (39)   
   RefSeq(nuc) (3)   
   GenBank (18)   
   EMBL (18)   
3D Structure (1)   
   PDB (1)   
Protein domain (7)   
   Pfam (7)   
All databases (71)   

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